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Results found that FOXM1 was up-regulated in gallbladder cancer (GBC) tissues and show that FOXM1 promotes cell invasion and cell cycle in GBC cells. Its expression is modulated by H19 (zeige NCKAP1 ELISA Kits) by targeting mir (zeige MLXIP ELISA Kits)-342.
FoxM1 regulates the expression of ADAM-17 (zeige ADAM17 ELISA Kits), which is upregulated in gastric carcinoma.
Results show that Gli1 (zeige GLI1 ELISA Kits) and FoxM1 expression levels are consistently elevated in human colorectal cancer (CRC (zeige CALR ELISA Kits)) tissues. Moreover, Gli1 (zeige GLI1 ELISA Kits) regulates the transcription of FoxM1 by directly binding to the promoter of FoxM1, which contributes to the proliferation of CRC (zeige CALR ELISA Kits) cells.
CTCF (zeige CTCF ELISA Kits)-FOXM1 axis regulates tumour growth and metastasis in hepatocellular carcinoma cells.
Data suggest forkhead box M1 (FOXM1)/eukaryotic elongation factor 2 kinase (eEF2K (zeige EEF2K ELISA Kits)) axis as a molecular target in breast and other cancers.
Together, these data identify FOXM1 as a key regulator of reactive oxygen species in normal dividing epithelial cells and suggest that squamous carcinoma cells may also use FOXM1 to control oxidative stress to escape premature senescence and apoptosis.
Overexpression of FOXM1 was associated with well-established markers of poor prognosis; thus FOXM1 may represent a potential novel prognostic marker for MBC (zeige DOCK2 ELISA Kits).
FOXM1 may play a central role in the skp2-cdk1 (zeige CDK1 ELISA Kits) loop driving tumor progression.
This study is the first to identify the roles of FOXM1 in drug efflux and paclitaxel resistance by regulating the gene transcription of abcc5 (zeige ABCC5 ELISA Kits), one of the ABC (zeige ABCB6 ELISA Kits) transporters. Small molecular inhibitors of FOXM1 or ABCC5 (zeige ABCC5 ELISA Kits) have the potential to overcome paclitaxel chemoresistance in nasopharyngeal carcinoma (NPC (zeige NPC1 ELISA Kits))patients.
Data suggest that forkhead box M1 (FOXM1) expression is biomarker, and its inhibition is a potential treatment option for synovial sarcoma (SS).
YAP (zeige YAP1 ELISA Kits) cooperates with FOXM1 to contribute to chromosome instability in hepatocellular carcinoma.
RCM-1 (zeige TNNI3 ELISA Kits) blocked the nuclear localization and increased the proteasomal degradation of Forkhead box M1 (FOXM1), a transcription factor critical for the differentiation of goblet cells from airway progenitor cells.
These data implicate the insulin (zeige INS ELISA Kits)-FoxM1/PLK1 (zeige PLK1 ELISA Kits)/CENP-A (zeige CENPA ELISA Kits) pathway-regulated mitotic cell-cycle progression as an essential component in the beta cell adaptation to delay and/or prevent progression to diabetes.
EGF (zeige EGF ELISA Kits) promotes FoxM1 expression through the ERK (zeige EPHB2 ELISA Kits) signal pathway
FoxM1 induction in the pulmonary vasculature was inhibited by a p110gamma (zeige PIK3CG ELISA Kits)-selective inhibitor and in Pik3cg (zeige PIK3CG ELISA Kits)(-/-) mice after LPS (zeige TLR4 ELISA Kits) challenge. Defective vascular repair in Pik3cg (zeige PIK3CG ELISA Kits)-/- mice results from impaired FoxM1 expression
we suggest that proper regional decidualization and polyploidy development requires FoxM1 signaling downstream of Hoxa10 (zeige HOXA10 ELISA Kits) and cyclin D3 (zeige CCND3 ELISA Kits).
FOXM1 and CENPF (zeige CENPF ELISA Kits) are master regulators of prostate cancer malignancy, and can serve as drug response markers for antineoplastic drugs efficiency.
Both gain-of-function and loss-of-function TP53 (zeige TP53 ELISA Kits) mutations contribute to overexpression of FoxM1 in high-grade serous ovarian cancer.
MicroRNA-802 suppresses breast cancer proliferation through down-regulation of FoxM1.
FoxM1 expression correlates with proliferation, invasion and migration in mouse hepatocellular carcinoma cell lines.
the sequence and expression pattern of FoxM1 (fork head box M1) transcription factor in Xenopus laevis embryos are described
Results suggest that FoxM1 functions to link cell division and neuronal differentiation in early Xenopus embryos.
The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene.
forkhead box protein M1
, forkhead box M1
, forkhead box protein M1-like
, Forkhead, drosophila, homolog-like 16
, HNF-3/fork-head homolog 11
, M-phase phosphoprotein 2
, MPM-2 reactive phosphoprotein 2
, forkhead-related protein FKHL16
, hepatocyte nuclear factor 3 forkhead homolog 11
, transcription factor Trident
, winged-helix factor from INS-1 cells
, forkhead homolog 16
, winged-helix transcription factor Trident
, INS-1 winged helix