Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Mouse (Murine) Antikörper:
anti-Rat (Rattus) Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal GLP2R Primary Antibody für WB - ABIN2787698
Sams, Hastrup, Andersen, Thim: Naturally occurring glucagon-like peptide-2 (GLP-2) receptors in human intestinal cell lines. in European journal of pharmacology 2006
Show all 2 Pubmed References
Age-dependent human beta cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling
Data suggest early peaks in glucagon-like peptide-1 (zeige GCG Antikörper) and glucagon (zeige GCG Antikörper) secretion/blood level together trigger exaggerated insulinotropic response (high insulin (zeige INS Antikörper) secretion/level) to eating and consequent hypoglycaemia in patients with postprandial hypoglycaemia as a postoperative complication following Roux-en-Y gastric bypass for obesity complicated by type 2 diabetes; this retrospective cohort study was conducted in London.
A common variant, i.e., single nucleotide polymorphism rs6741949, in the DPP4 (zeige DPP4 Antikörper) gene interacts with body adiposity and negatively affects glucose-stimulated GLP-1 (zeige GCG Antikörper) levels, insulin (zeige INS Antikörper) secretion, and glucose tolerance.
Compared with the lean group, the obese group had significantly higher fasting and post-OGTT GIP (zeige GIP Antikörper) levels, but similar fasting GLP-1 (zeige GCG Antikörper) and significantly lower post-OGTT GLP-1 (zeige GCG Antikörper) levels.
Hemodialysis improves upper GI symptoms and gastric slow waves in CKD patients. An increase in ghrelin (zeige GHRL Antikörper) and a decrease in GLP-1 (zeige GCG Antikörper) might be involved in the HD-induced improvement in gastric slow waves.
Data suggest that, in obesity, serum levels of active GLP1 (zeige GCG Antikörper) are down-regulated and serum levels of soluble DPP4 (zeige DPP4 Antikörper) are up-regulated; DPP4 (zeige DPP4 Antikörper) levels correlate negatively with active GLP-1 (zeige GCG Antikörper) levels but are positively associated with insulin (zeige INS Antikörper) resistance; thus, DPP4 (zeige DPP4 Antikörper) may be biomarker for insulin (zeige INS Antikörper) resistance. This study was conducted in Malaysia. (GLP1 (zeige GCG Antikörper) = glucagon-like peptide 1 (zeige GCG Antikörper); DPP4 (zeige DPP4 Antikörper) = dipeptidyl peptidase 4 (zeige DPP4 Antikörper))
Insulin (zeige INS Antikörper) resistance, postprandial GLP-1 (zeige GCG Antikörper) and adaptive immunity are the main predictors of NAFLD (zeige TSC2 Antikörper) in a homogeneous population at high cardiovascular risk.
Data suggest that laparoscopic sleeve gastrectomy (LSG) for morbid obesity improves insulin resistance after either fast or slow feeding/eating; these findings suggest a negligible contribution of anorexigenic gut peptides GLP1 (glucagon-like peptide 1) and PYY (peptide YY) from intestinal L cells in response to LSG-induced weight loss.
L-trp (zeige TBPL1 Antikörper) is a luminal regulator of CCK (zeige CCK Antikörper) release with effects on gastric emptying, an effect that could be mediated by CCK (zeige CCK Antikörper). L-trp's effect on GLP-1 (zeige GCG Antikörper) secretion is only minor. At the doses given, the two amino acids did not affect subjective appetite feelings.
The effects of GLP-1 (zeige GCG Antikörper)-based therapies on blood glucose in type 2 diabetics are not mediated through microvascular responses.
Results suggest that GLP-2 (zeige GCG Antikörper) protected and improved memory function in LPS (zeige TLR4 Antikörper)-treated mice, and also had anxiolytic effects due to changes in the 5-HT (zeige DDC Antikörper) system.
Report gastrointestinal GLP-2 receptor andl limited utility of GLP-2 in the management of inflammatory intestinal disorders.
GLP-2 (zeige GCG Antikörper) plays a key physiological role in the control of hepatic glucose production through activating PI3K-dependent modulation of membrane excitability and nuclear transcription of POMC (zeige POMC Antikörper) neurons in the brain.
Data suggest a role for endogenous GLP2 (glucagon-like peptide-2 (zeige GCG Antikörper)) and GLP2R in adaptation of mucosa of duodenum and jejunum to high-fat diet; results suggest dysregulation of GLP2/GLP2R signaling in obesity due to prolonged high-fat diet.
The data indicated that CNS GLP-2 receptor plays a physiological role in the control of feeding behavior and gastric emptying and that this is mediated probably through the melanocortin system.
Data suggest that the Vip (zeige Vip Antikörper) gene is not required for induction of a gene expression program linked to small bowel growth after enhancement of GLP-2 receptor signaling.
Disruption of the murine Glp2r impairs Paneth cell function and increases susceptibility to small bowel enteritis
Data show that the GLP-2R is expressed by inhibitory and excitatory neurons, and inhibits the muscle contractility likely by decreasing cholinergic neurotransmission and increasing nitric oxide production.
GLP-2R is not critical for the stimulation/suppression of glucagon (zeige GCG Antikörper) secretion or glucose homeostasis in normal or lean diabetic mice. In obese mice GLP-2R signaling mediates the normal islet adaptive response required to maintain glucose homeostasis.
Glucagon-like peptide-2 (zeige GCG Antikörper) potentiates L-type voltage-gated Ca(2 (zeige CA2 Antikörper)+) channels activity through activating cAMP-dependent protein kinase A signaling, partially stimulating glucose uptake by primary cultured hippocampal neurons.
data demonstrate that cattle express proglucagon (zeige GCG Antikörper) and glucagon-like peptide 2 receptor mRNA primarily in small intestinal and colon tissues
The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R).
glucagon-like peptide 2 receptor
, glicentin-related polypeptide
, glucagon-like peptide 1
, glucagon-like peptide 2
, GLP-2 receptor
, G protein-coupled receptor GLP2R
, glucagon-like peptide-2 receptor