anti-DACT1 (DACT1) Antikörper

Bezeichnung:
anti-Dapper, Antagonist of beta-Catenin, Homolog 1 (Xenopus Laevis) Antikörper (DACT1)
Auf www.antikoerper-online.de finden Sie aktuell 40 Dapper, Antagonist of beta-Catenin, Homolog 1 (Xenopus Laevis) (DACT1) Antikörper von 11 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen DACT1 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 45 DACT1 Produkte verfügbar.
Synonyme:
4921528D17Rik, AI115603, dact1, DAPPER, DAPPER1, dpr, DPR1, frd1, FRODO, frodo1, HDPR1, MDpr1, MGC89695, MTNG3, RGD1564008, THYEX3, XDpr, XDpr1a
Alle Antikörper anzeigen Gen GeneID UniProt
DACT1 59036 Q8R4A3
DACT1 51339 Q9NYF0
DACT1 500666  

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-DACT1 (DACT1) Antikörper

Wählen Sie die Spezies und Applikation aus

anti-Mouse (Murine) DACT1 Antikörper:

anti-Human DACT1 Antikörper:

anti-Rat (Rattus) DACT1 Antikörper:

Alle verfügbaren anti-DACT1 Antikörper

Sie gelangen zu unserer vorgefilterten Suche.

Am meisten referenzierte anti-DACT1 Antikörper

  1. Mouse (Murine) Polyclonal DACT1 Primary Antibody für WB - ABIN2473224 : Suriben, Kivimäe, Fisher, Moon, Cheyette: Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak. in Nature genetics 2009 (PubMed)

Weitere Antikörper gegen DACT1 Interaktionspartner

Mouse (Murine) Dapper, Antagonist of beta-Catenin, Homolog 1 (Xenopus Laevis) (DACT1) Interaktionspartner

  1. Dpr1 promotes the ubiquitination of Dvl2 (zeige DVL2 Antikörper) by pVHL (zeige VHL Antikörper) and mediates the protein aggregate-elicited autophagy initiation

  2. Expression analysis of Dact1-LacZ (zeige GLB1 Antikörper) show high expression levels in multiple mesoderm- and neuroectoderm-derived tissues during embryonic development, but restricted to a small number of postnatal tissues.

  3. These results support a novel cell-autonomous postsynaptic role for Dact1, in cooperation with Dishevelled-1 (zeige DVL1 Antikörper) and possibly Disrupted in Schizophrenia-1 (zeige DISC1 Antikörper), in the formation of synapses on cortical interneuron dendrites.

  4. Depletion of Dapper-1 and dishevelled-2 (zeige DVL2 Antikörper) in cardiomyocytes demonstrated that Dapper-1 functions upstream of dishevelled-2 (zeige DVL2 Antikörper) and that activity of both Dapper-1 and dishevelled-2 (zeige DVL2 Antikörper) is essential for activating canonical Wnt (zeige WNT2 Antikörper) signaling.

  5. conserved role for Dact1 protein in kinase-regulated biochemistry involving Vangl and Dvl (zeige DVL1 Antikörper).

  6. Dact1 was upregulated in the dental follicle mesenchyme at the cap stage and subsequently also in the dental papilla at the bell stage, where the expression persisted to the postnatal stages.

  7. Loss of Dact1 disrupts planar cell polarity signaling by altering dishevelled (zeige DVL2 Antikörper) activity and leads to posterior malformation in mice.

  8. This study shown that Dact1 plays an important role during dendrite and spine formation in neurons of the mammalian forebrain by promoting activation of Rac (zeige AKT1 Antikörper)

  9. Frodo is expressed in primitive streak mesoderm, neuroectoderm, neural crest, presomitic mesoderm, and somites. In many cases, Frodo expression is confined to tissues undergoing extensive morphogenesis

  10. Dact1 is detected in the presomitic mesoderm and somites during segmentation, in the limb bud mesenchyme and other mesoderm-derived tissues, and in the central nervous system

Zebrafish Dapper, Antagonist of beta-Catenin, Homolog 1 (Xenopus Laevis) (DACT1) Interaktionspartner

  1. frd1 is expressed in the developing brain and mesoderm.

  2. two Dvl (zeige DVL2 Antikörper)-associated paralogs, Dpr1 and Dpr2 (zeige DACT2 Antikörper), participate in distinct Wnt (zeige WNT2 Antikörper)-dependent developmental processes

  3. target of beta-catenin (zeige CTNNB1 Antikörper) and/or an unknown downstream effector in development

Human Dapper, Antagonist of beta-Catenin, Homolog 1 (Xenopus Laevis) (DACT1) Interaktionspartner

  1. Dact1 is up-regulated by TGF-beta1 (zeige TGFB1 Antikörper), inducing apoptosis in mesangial cells.

  2. The simultaneous methylation of DACT1 and DACT2 (zeige DACT2 Antikörper) may play important roles in progression of ESCC and may serve as prognostic methylation biomarkers for ESCC patients.

  3. Dact1 has a critical role in the ability support keratinocyte proliferation, by attenuating Wnt (zeige WNT2 Antikörper)/beta catenin (zeige CTNNB1 Antikörper) signaling.

  4. our results suggested that DACT1 was upregulated during human placenta development.

  5. There was no statistical difference between groups concerning DACT1 and DACT2 (zeige DACT2 Antikörper) either in promoter hypermethylation or transcript levels. Age was associated with DACT2 (zeige DACT2 Antikörper) promoter hypermethylation, especially over 56 years old.

  6. Dpr1 promotes the ubiquitination of Dvl2 (zeige DVL2 Antikörper) by pVHL (zeige VHL Antikörper) and mediates the protein aggregate-elicited autophagy initiation

  7. Overexpression of Dapper-1 allows the translocation of MIZ-1 (zeige ZBTB17 Antikörper) from the nucleus to the cytoplasm.

  8. Dpr1 directly interacts with Beclin1 (zeige BECN1 Antikörper) and Atg14L and enhances the Beclin1 (zeige BECN1 Antikörper)-Vps34 (zeige PIK3C3 Antikörper) interaction and Vps34 (zeige PIK3C3 Antikörper) activity.

  9. Data indicate that Sestd1 (zeige SESTD1 Antikörper) cooperates with Dact1 in Vangl2 (zeige VANGL2 Antikörper) regulation and in the planar cell polarity (PCP (zeige PRCP Antikörper)) pathway during mammalian embryonic development.

  10. five missense heterozygote mutations of the DACT1 gene are specifically identified in 167 stillborn or miscarried Han Chinese fetuses with neural tube defects.

DACT1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with DACT1

  • dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) (DACT1) Antikörper
  • dapper, antagonist of beta-catenin (dact1) Antikörper
  • dishevelled-binding antagonist of beta-catenin 1 (DACT1) Antikörper
  • dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) (dact1) Antikörper
  • dapper homolog 1, antagonist of beta-catenin (xenopus) (Dact1) Antikörper
  • dapper homolog 1, antagonist of beta-catenin (xenopus) (dact1) Antikörper
  • dishevelled-binding antagonist of beta-catenin 1 (dact1-b) Antikörper
  • dishevelled-binding antagonist of beta-catenin 1 (Dact1) Antikörper
  • 4921528D17Rik Antikörper
  • AI115603 Antikörper
  • dact1 Antikörper
  • DAPPER Antikörper
  • DAPPER1 Antikörper
  • dpr Antikörper
  • DPR1 Antikörper
  • frd1 Antikörper
  • FRODO Antikörper
  • frodo1 Antikörper
  • HDPR1 Antikörper
  • MDpr1 Antikörper
  • MGC89695 Antikörper
  • MTNG3 Antikörper
  • RGD1564008 Antikörper
  • THYEX3 Antikörper
  • XDpr Antikörper
  • XDpr1a Antikörper

Bezeichner auf Proteinebene für DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) , dapper 1 , dapper, antagonist of beta-catenin , dapper, antagonist of beta-catenin, homolog 1 , dapper homolog 1-like , dapper antagonist of catenin 1 , dapper homolog 1 , frodo homolog , thymus expressed gene 3 , thymus-expressed novel gene 3 protein , dishevelled-interacting protein , frodo 1 , hepatocellular carcinoma novel gene 3 protein , heptacellular carcinoma novel gene 3 , dapper 1-B , dapper1a , xDpr , dapper homolog 1, antagonist of beta-catenin

GENE ID SPEZIES
452938 Pan troglodytes
493325 Xenopus (Silurana) tropicalis
538778 Bos taurus
701218 Macaca mulatta
100021268 Monodelphis domestica
100339172 Oryctolagus cuniculus
100400795 Callithrix jacchus
100437942 Pongo abelii
100546955 Meleagris gallopavo
100555885 Anolis carolinensis
100606126 Nomascus leucogenys
59036 Mus musculus
405799 Danio rerio
723789 Gallus gallus
100687551 Canis lupus familiaris
51339 Homo sapiens
399186 Xenopus laevis
500666 Rattus norvegicus
Ausgewählte Anbieter für anti-DACT1 (DACT1) Antikörper
Haben Sie etwas anderes gesucht?