PIK3CA (PIK3CA) ELISA Kits

Bezeichnung:
Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide ELISA Kits (PIK3CA)
Auf www.antikoerper-online.de finden Sie aktuell 10 Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) ELISA Kits von 5 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PIK3CA Antikörper (163) und PIK3CA Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 186 PIK3CA Produkte verfügbar.
Synonyme:
6330412C24Rik, C-P3K, caPI3K, CLOVE, CWS5, MCAP, MCM, MCMTC, p110, p110-alpha, p110alpha, pi3-k, PI3-kinase, PI3K, PI3K-alpha
list all ELISA KIts Gen GeneID UniProt
PIK3CA 18706 P42337
PIK3CA 5290 P42336
Ratte PIK3CA PIK3CA 170911  

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PIK3CA (PIK3CA) ELISA Kits nach Reaktivitäten

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Weitere ELISA Kits für PIK3CA Interaktionspartner

Mouse (Murine) Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) Interaktionspartner

  1. Studies indicate that the Pten+/- genotype displayed neoplasia in multiple organs, including the endometrium and that the Pten is a key regulatory player in the PI3K/PTEN/AKT (zeige AKT1 ELISA Kits) pathway.

  2. our results offer significant insight into how PIK3CA overexpression drives squamous cell carcinoma (HNSCC) invasion and metastasis, providing a rationale for targeting PI3K/PDK1 (zeige PDPK1 ELISA Kits) and TGFb (zeige TGFB1 ELISA Kits) signaling in advanced HNSCC patients with PIK3CA amplification

  3. Data show that docetaxel, rapamycin and tanespimycin multi-drug loaded micelles targeted against HSP90 (zeige HSP90 ELISA Kits) and the PI3K/AKT (zeige AKT1 ELISA Kits)/mTOR (zeige FRAP1 ELISA Kits) pathway in prostate cancer.

  4. Data indicate that chlorogenic acid (CGA (zeige CGA ELISA Kits)) protected osteoblast MC3T3-E1 cells against oxidative damage via PI3K/Akt (zeige AKT1 ELISA Kits)-mediated activation of Nrf2 (zeige NFE2L2 ELISA Kits)/HO-1 (zeige HMOX1 ELISA Kits) pathway, which may be an effective drug in treatment of osteoporosis.

  5. Data show that macrophage M2 polarization was mediated through PTEN/PI3k/AKT (zeige AKT1 ELISA Kits) pathway activation.

  6. Constitutive Activation of PI3K is associated with Ovarian Granulosa Cell Tumors.

  7. Together with recent identification of somatic mutations in p110a (encoded by PIK3CA), our data establish a potential mechanistic link between AGGF1 (zeige AGGF1 ELISA Kits) and PIK3CA, the two genes identified for Klippel-Trenaunay syndrome (KTS)

  8. p110beta has a role in mediating skeletal muscle metabolic signaling by regulating expression of AMP-activated protein kinase (zeige PRKAA2 ELISA Kits)

  9. The mRNA levels of leptin (zeige LEP ELISA Kits) and of 17-beta-dehydrogenase 3, and enzyme important for testosterone production, were significantly higher in the testis of adult alpha-/- males( PI3K catalytic subunit p110alpha deletion).

  10. Results suggest a role of ST6GalNAc I (zeige ST6GALNAC1 ELISA Kits) in promoting the growth and invasion of hepatocarcinoma cells through regulating PI3K/AKT (zeige AKT1 ELISA Kits)/NF-kappa B (zeige NFKB1 ELISA Kits) signaling, and ST6GalNAc I (zeige ST6GALNAC1 ELISA Kits) might be a marker for the prognosis and therapy of hepatocarcinoma.

Human Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) Interaktionspartner

  1. High PI3K expression is associated with melanoma.

  2. Data indicate that PI3K pathway mutation predicts longer time to local progression after radioembolization of colorectal liver metastases.

  3. Oncogenic beta-catenin (zeige CTNNB1 ELISA Kits) and PI3K activities interact in the acquisition of multiple cancer-related phenotypes in organoids grown in Matrigel.

  4. Results indicate that p110alpha primarily mediates PI3K/AKT (zeige AKT1 ELISA Kits) signaling in HER2 (zeige ERBB2 ELISA Kits)+ PTEN deficient breast tumors whereas p110beta conditionally mediates HER2 (zeige ERBB2 ELISA Kits)/PI3K signaling in the absence of p110alpha.

  5. Cytokines IL-2 (zeige IL2 ELISA Kits)/7/9 stimulation activates PI3K/Akt (zeige AKT1 ELISA Kits) pathways downstream of Ras in RasGRP1 (zeige RASGRP1 ELISA Kits) T-cell acute lymphoblastic leukemia (T-ALL).

  6. This study revealed that (1) PIK3CA hotspot mutations occurred with low frequency in gastric cancer; (2) PIK3CA hotspot mutations were not directly associated with PI3K pathway activation; and (3) p-AKT (zeige AKT1 ELISA Kits) (+) may be a biomarker for better outcomes for gastric cancer patients undergoing gastrectomy regardless of the PIK3CA mutation status.

  7. Findings indicate that Epstein-Barr virus(EBV)-encoded latent membrane protein 1 (LMP1 (zeige PDLIM7 ELISA Kits)), PI3K/AKT (zeige AKT1 ELISA Kits), miR (zeige MLXIP ELISA Kits)-21 and PTEN constitute a positive feedback loop and have a key role in LMP1 (zeige PDLIM7 ELISA Kits)-induced cancer stem cells (CSCs) in nasopharyngeal carcinoma (NPC (zeige NPC1 ELISA Kits)).

  8. Data suggest that Lys-776 (in the P-loop of PIK3CA) is critical for autophosphorylation in PIK3CA/PIK3R1 heterodimer; both His-936 and His-917 (in the activation and catalytic loops of PIK3CA) are important catalytically, but appear to have different functions; bisubstrate kinetic analysis of PIK3CA/PIK3R1 heterodimer indicates an ordered sequential mechanism.

  9. PIK3CA mutation is associated with endometrial carcinoma progression and abdominopelvic metastasis.

  10. Tetraarsenic hexoxide (As4O6) induced G2/M arrest, apoptosis and autophagic cell death through PI3K/Akt (zeige AKT1 ELISA Kits) and p38 MAPK (zeige MAPK14 ELISA Kits) pathways alteration in SW620 colon cancer cells.

Cow (Bovine) Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) Interaktionspartner

  1. There are multiple conformations in equilibrium during the course of PI3K SH3 domain (zeige ITSN1 ELISA Kits) unfolding.

  2. PI3K has a role in activation of 5'-AMP (zeige TMPRSS5 ELISA Kits)-activated kinase during hypoxia-reoxygenation of bovine aortic endothelial cells

  3. Production of PtdIns3P by PI3K-C2alpha (zeige PIK3C2A ELISA Kits) is required for acquisition of fusion competence in neurosecretion.

  4. crystallographic and biochemical approaches used to gain insight into activating mutations in two noncatalytic p110alpha domains-the adaptor-binding and the helical domains

PIK3CA Antigen-Profil

Beschreibung des Gens

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.

Alternative names and synonyms associated with PIK3CA

  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (PIK3CA) Elisa Kit
  • Phosphoinositide-3-kinase, catalytic, alpha polypeptide (GL50803_14855) Elisa Kit
  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (pik3ca) Elisa Kit
  • phosphoinositide-3-kinase, catalytic, alpha polypeptide (LOC100337822) Elisa Kit
  • phosphatidylinositol 3-kinase, catalytic, alpha polypeptide (Pik3ca) Elisa Kit
  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (Pik3ca) Elisa Kit
  • phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA) Elisa Kit
  • 6330412C24Rik Elisa Kit
  • C-P3K Elisa Kit
  • caPI3K Elisa Kit
  • CLOVE Elisa Kit
  • CWS5 Elisa Kit
  • MCAP Elisa Kit
  • MCM Elisa Kit
  • MCMTC Elisa Kit
  • p110 Elisa Kit
  • p110-alpha Elisa Kit
  • p110alpha Elisa Kit
  • pi3-k Elisa Kit
  • PI3-kinase Elisa Kit
  • PI3K Elisa Kit
  • PI3K-alpha Elisa Kit

Bezeichner auf Proteinebene für PIK3CA

phosphoinositide-3-kinase, catalytic, alpha polypeptide , Phosphoinositide-3-kinase, catalytic, alpha polypeptide , PI3-kinase subunit alpha , PI3K-alpha , PI3Kalpha , phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha , phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform , phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha , phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform , phosphoinositide-3-kinase catalytic alpha polypeptide , ptdIns-3-kinase subunit alpha , ptdIns-3-kinase subunit p110-alpha , serine/threonine protein kinase PIK3CA , PI3-kinase p110 subunit alpha , phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha , phosphatidylinositol 3-kinase, catalytic, alpha polypeptide , phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform , PI3K , p110alpha , ptdIns-3-kinase p110 , phosphoinositide 3-kinase catalytic subunit

GENE ID SPEZIES
460858 Pan troglodytes
5702156 Giardia lamblia ATCC 50803
100144924 Xenopus (Silurana) tropicalis
100229768 Taeniopygia guttata
100337822 Oryctolagus cuniculus
18706 Mus musculus
5290 Homo sapiens
282306 Bos taurus
170911 Rattus norvegicus
488084 Canis lupus familiaris
424971 Gallus gallus
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