anti-Human MTOR Antikörper für Dot Blot

Recommended MTOR Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antikörper
  • FRAP1
  • FRAP
  • FRAP2
  • RAFT1
  • RAPT1
  • 2610315D21Rik
  • AI327068
  • Frap1
  • flat
  • frap1
  • tor
  • wu:fc22h08
  • mechanistic target of rapamycin (serine/threonine kinase)
  • MTOR
  • Mtor
  • mtor
Epitop
pThr2446
64
27
26
22
21
20
15
15
12
10
9
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
368
201
199
18
9
8
7
7
7
7
4
2
2
2
1
1
Wirt
Kaninchen
316
48
3
1
Klonalität
Polyklonal
Konjugat
Dieser MTOR Antikörper ist unkonjugiert
8
8
7
5
4
4
4
4
4
4
4
4
4
4
4
4
3
3
Applikation
Dot Blot (DB)
247
111
94
73
55
52
37
20
7
7
7
6
3
2
2
1
1
1
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN1881353
335,24 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2794213 DB Rabbit Ig Fraction pThr2446 Anmelden zum Anzeigen Polyclonal

anti-MTOR Antikörper für Dot Blot mit den meisten Publikationen

Ähnliche anti-MTOR Antikörper

Applikation / Reaktivität Human
Chromatin Immunoprecipitation (ChIP) 1 Antikörper
Dot Blot (DB) 2 Antikörper
Electron Microscopy (EM) 1 Antikörper
ELISA 94 Antikörper
Enzyme Immunoassay (EIA) 7 Antikörper
Flow Cytometry (FACS) 6 Antikörper
Immunochromatography (IC) 7 Antikörper
Immunocytochemistry (ICC) 20 Antikörper
Immunofluorescence (IF) 55 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 7 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 52 Antikörper
Immunohistochemistry (IHC) 111 Antikörper
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 73 Antikörper
Immunoprecipitation (IP) 37 Antikörper
Intracellular Flow Cytometry (ICFC) 2 Antikörper
Mass Cytometry (CyTOF) 2 Antikörper
Proximity Ligation Assay (PLA) 3 Antikörper

General

Antigen Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antikörper
Epitop pThr2446
(64), (27), (26), (22), (21), (20), (15), (15), (12), (10), (9), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(368), (201), (199), (18), (9), (8), (7), (7), (7), (7), (4), (2), (2), (2), (1), (1)
Wirt Kaninchen
(316), (48), (3), (1)
Klonalität (Klon)
Polyklonal   ( )
Konjugat Dieser MTOR Antikörper ist unkonjugiert
(8), (8), (7), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3)
Applikation Dot Blot (DB)
(247), (111), (94), (73), (55), (52), (37), (20), (7), (7), (7), (6), (3), (2), (2), (1), (1), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-MTOR Antikörper

Target Details MTOR Anwendungsinformationen Handhabung ProductDetails: References for anti-MTOR antibody (ABIN1881353) Bilder
Homologie Mouse (Murine),Rat (Rattus)
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This FRAP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T2446 of human FRAP1.
Klon RB13089

Target Details MTOR

Produktdetails anti-MTOR Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-MTOR antibody (ABIN1881353) Bilder zurück nach oben
Antigen
Andere Bezeichnung FRAP1 (FRAP1 Antibody Abstract)
Hintergrund FRAP1 belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. FRAP1 is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.

Synonyms: MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1, Serine/threonine-protein kinase mTOR, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1
NCBI Accession NP_004949
UniProt P42345
Pathways PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events

Anwendungsinformationen

Produktdetails anti-MTOR Antikörper Target Details MTOR Handhabung ProductDetails: References for anti-MTOR antibody (ABIN1881353) Bilder zurück nach oben
Applikationshinweise DB: 1:500
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-MTOR Antikörper Target Details MTOR Anwendungsinformationen ProductDetails: References for anti-MTOR antibody (ABIN1881353) Bilder zurück nach oben
Format Liquid
Konzentration 0.45 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

ProductDetails: References for anti-MTOR antibody (ABIN1881353)

Produktdetails anti-MTOR Antikörper Target Details MTOR Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Pillai, Sundaresan, Kim, Gupta, Rajamohan, Pillai, Samant, Ravindra, Isbatan, Gupta: "Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway." in: The Journal of biological chemistry, Vol. 285, Issue 5, pp. 3133-44, 2010

Dowling, Zakikhani, Fantus, Pollak, Sonenberg: "Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells." in: Cancer research, Vol. 67, Issue 22, pp. 10804-12, 2007

Bai, Ma, Liu, Shen, Wang, Liu, Jiang: "Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38." in: Science (New York, N.Y.), Vol. 318, Issue 5852, pp. 977-80, 2007

Zhou, Wulfkuhle, Zhang, Gu, Yang, Deng, Margolick, Liotta, Petricoin, Zhang: "Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 41, pp. 16158-63, 2007

Bilder

Produktdetails anti-MTOR Antikörper Target Details MTOR Anwendungsinformationen Handhabung ProductDetails: References for anti-MTOR antibody (ABIN1881353) zurück nach oben
Bilder des Herstellers
Dot Blot (DB) image for anti-MTOR Antikörper (Mechanistic Target of Rapamycin (serine/threonine Kinase)) (pThr2446) (ABIN1881353) Dot blot analysis of anti-FRAP1-pT2446 Phospho-specific Pab (Cat.AP3433a) on nitrocel...