anti-Hund MTOR Antikörper für Immunofluorescence

Recommended MTOR Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antikörper
  • FRAP1
  • FRAP
  • FRAP2
  • RAFT1
  • RAPT1
  • 2610315D21Rik
  • AI327068
  • Frap1
  • flat
  • frap1
  • tor
  • wu:fc22h08
  • mechanistic target of rapamycin (serine/threonine kinase)
  • MTOR
  • Mtor
  • mtor
Epitop
AA 2440-2457
64
28
26
22
21
20
15
15
11
10
9
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Hund, Human, Maus, Ratte (Rattus), Zebrafisch (Danio rerio)
368
200
198
18
8
8
7
7
7
7
4
2
2
1
1
1
Wirt
Kaninchen
316
48
3
1
Klonalität
Polyklonal
Konjugat
Dieser MTOR Antikörper ist unkonjugiert
8
8
7
5
4
4
4
4
4
4
4
4
4
4
4
4
3
3
Applikation
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
246
111
94
72
54
52
37
20
7
7
6
6
3
2
2
2
1
1
1
Hersteller
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Bilder

Produktnummer ABIN303334
517,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1915272 ICC IF IP PLA Rabbit IgG AA 200-250 Anmelden zum Anzeigen Polyclonal

Ähnliche anti-MTOR Antikörper

Applikation / Reaktivität Human Maus Ratte (Rattus) Hund Zebrafisch (Danio rerio)
Immunofluorescence (fixed cells) (IF/ICC) 7 Antikörper 4 Antikörper 4 Antikörper
Western Blotting (WB) 247 Antikörper 111 Antikörper 107 Antikörper 6 Antikörper 2 Antikörper
Proximity Ligation Assay (PLA) 3 Antikörper 2 Antikörper 1 Antikörper 1 Antikörper
Mass Cytometry (CyTOF) 2 Antikörper

General

Antigen Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antikörper
Epitop AA 2440-2457
(64), (28), (26), (22), (21), (20), (15), (15), (11), (10), (9), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Hund, Human, Maus, Ratte (Rattus), Zebrafisch (Danio rerio)
(368), (200), (198), (18), (8), (8), (7), (7), (7), (7), (4), (2), (2), (1), (1), (1)
Wirt Kaninchen
(316), (48), (3), (1)
Klonalität
Polyklonal
Konjugat Dieser MTOR Antikörper ist unkonjugiert
(8), (8), (7), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3)
Applikation Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(246), (111), (94), (72), (54), (52), (37), (20), (7), (7), (6), (6), (3), (2), (2), (2), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-MTOR Antikörper

Target Details MTOR Anwendungsinformationen Handhabung Bilder
Spezifität This antibody recognises MTOR.
Kreuzreaktivität (Details) Species reactivity (expected):Mouse, Rat, Canine (Dog) and Zebrafish.
Species reactivity (tested):Human.
Reinigung Immunoaffinity Chromatography
Immunogen Synthetic Peptide corresponding to Amino acids 2440-2457 of human mTOR.

Target Details MTOR

Produktdetails anti-MTOR Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung mTOR / FRAP1 (FRAP1 Antibody Abstract)
Hintergrund The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. It was initially discovered as a kinase whose ability to stimulate T cell proliferation in response to IL-2 could be inhibited by the immunosuppressive drug rapamycin. Rapamycin inhibits TOR in other cell types resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation. TOR is normally associated with the regulatory proteins RAPTOR and GbL. Its downstream targets are thought to be the ribosomal protein S6 kinases and the eukaryotic initiation factor 4E binding proteins (4EBPs). Regulation of these protein families allows TOR to control protein biosynthesis.Synonyms: FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, FRAP, FRAP2, Mammalian target of rapamycin, RAPT1, Rapamycin target protein, Serine/threonine-protein kinase mTOR, TOR
Gen-ID 2475
NCBI Accession NP_004949
UniProt P42345
Pathways PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events

Anwendungsinformationen

Produktdetails anti-MTOR Antikörper Target Details MTOR Handhabung Bilder zurück nach oben
Applikationshinweise Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Immunofluorescence. Western Blot (1/250-1/2000). ELISA (1/4000-1/20000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-MTOR Antikörper Target Details MTOR Anwendungsinformationen Bilder zurück nach oben
Konzentration 0,6 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Bilder

Produktdetails anti-MTOR Antikörper Target Details MTOR Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
 image for anti-MTOR Antikörper (Mechanistic Target of Rapamycin (serine/threonine Kinase)) (AA 2440-2457) (ABIN303334) anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) (AA 2440-2457) antibody
 image for anti-MTOR Antikörper (Mechanistic Target of Rapamycin (serine/threonine Kinase)) (AA 2440-2457) (ABIN303334) anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) (AA 2440-2457) antibody (Image 2)