anti-Human MLST8 Antikörper für Enzyme Immunoassay

Recommended MLST8 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
MTOR Associated Protein, LST8 Homolog (S. Cerevisiae) (MLST8) Antikörper
  • gbl
  • lts8
  • GBL
  • GbetaL
  • LST8
  • POP3
  • WAT1
  • 0610033N12Rik
  • AA409454
  • AI505104
  • AI851821
  • Gbl
  • fi37e04
  • wu:fi37e04
  • zgc:55455
  • zgc:85668
  • MTOR associated protein, LST8 homolog
  • MTOR associated protein, LST8 homolog (S. cerevisiae)
  • mlst8
  • MLST8
  • Mlst8
Reaktivität
Human, Maus, Ratte (Rattus)
117
64
46
10
9
8
5
4
4
3
3
3
3
3
2
2
2
1
1
1
1
Wirt
Kaninchen
110
18
2
Klonalität
Polyklonal
Konjugat
Dieser MLST8 Antikörper ist unkonjugiert
7
7
6
5
5
5
1
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
109
44
33
15
13
9
5
3
2
2
1
Hersteller
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Produktnummer ABIN5554818
357,50 €
Zzgl. Versandkosten 20,00 € und MWSt

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General

Antigen MTOR Associated Protein, LST8 Homolog (S. Cerevisiae) (MLST8) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(117), (64), (46), (10), (9), (8), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Wirt Kaninchen
(110), (18), (2)
Klonalität
Polyklonal
Konjugat Dieser MLST8 Antikörper ist unkonjugiert
(7), (7), (6), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(109), (44), (33), (15), (13), (9), (5), (3), (2), (2), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-MLST8 Antikörper

Target Details MLST8 Anwendungsinformationen Handhabung Bilder
Spezifität GbL antibody was raised against a 14 amino acid peptide from near the carboxy-terminus of human GbL.
Reinigung Affinity chromatography purified via peptide column
Immunogen Human GbL / G beta protein subunit-like Peptide
Isotyp IgG

Target Details MLST8

Produktdetails anti-MLST8 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung LST8 / GBL (MLST8 Antibody Abstract)
Hintergrund GbetaL (G protein beta protein subunit-like) is a member of a signaling pathway that regulates mammalian cell growth in response to the presence of nutrients and growth factors (1). It binds to the kinase domain of TOR (Target of rapamycin, also known as mTOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors (reviewed in 2). Rapamycin inhibits TOR resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation (reviewed in 3). TOR is normally associated with GβL and an additional regulatory protein RAPTOR, allowing TOR to control protein biosynthesis (3). The binding of GβL to TOR stimulates TOR's kinase activity towards downstream proteins such as RPS6K (ribosomal protein S6 kinase) and the translation factor 4E-BP1 which leads to increased protein translation and cell growth (3).Synonyms: G protein beta subunit-like, Gable, Mammalian lethal with SEC13 protein 8, Protein GbetaL, TORC subunit LST8, Target of rapamycin complex subunit LST8, mLST8
Gen-ID 64223
UniProt Q9BVC4
Pathways PI3K-Akt Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Autophagie, CXCR4-mediated Signaling Events

Anwendungsinformationen

Produktdetails anti-MLST8 Antikörper Target Details MLST8 Handhabung Bilder zurück nach oben
Applikationshinweise ELISA. Western Blot: 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-MLST8 Antikörper Target Details MLST8 Anwendungsinformationen Bilder zurück nach oben
Buffer PBS containing 0.02 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C.