anti-Human GSK3 alpha Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended GSK3 alpha Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Glycogen Synthase Kinase 3 alpha (GSK3a) Antikörper
  • GSK3A
  • CG5182
  • Dmel\\CG5182
  • GSK3a
  • 2700086H06Rik
  • xgsk3
  • GSK-3[a]
  • GSK-3[b]
  • GSK3
  • gsk3a
  • glycogen synthase kinase 3 alpha
  • CG5182 gene product from transcript CG5182-RA
  • glycogen synthase kinase 3 alpha b
  • GSK3A
  • gsk3a
  • Bm1_31380
  • Pk34A
  • Gsk3a
  • LOC100339192
  • gsk3ab
Epitop
AA 1-50, pSer21
68
36
25
14
11
9
7
7
6
5
5
4
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
310
161
133
7
7
6
4
4
3
1
1
1
1
Wirt
Kaninchen
217
119
3
Klonalität
Polyklonal
Konjugat
Dieser GSK3 alpha Antikörper ist unkonjugiert
24
13
12
7
6
6
4
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
297
152
138
58
50
48
32
12
7
7
5
4
3
1
Optionen
Hersteller
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Bilder

Produktnummer ABIN708116
$ 317.90
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN874843 IF (p) Alexa Fluor 350 Rabbit IgG AA 1-50, pSer21 Anmelden zum Anzeigen Polyclonal
1 ABIN874838 IF (p) Alexa Fluor 488 Rabbit IgG AA 1-50, pSer21 Anmelden zum Anzeigen Polyclonal
1 ABIN874841 IF (p) Alexa Fluor 555 Rabbit IgG AA 1-50, pSer21 Anmelden zum Anzeigen Polyclonal
1 ABIN874839 IF (p) Alexa Fluor 647 Rabbit IgG AA 1-50, pSer21 Anmelden zum Anzeigen Polyclonal
1 ABIN708122 IF (p) Cy7 Rabbit IgG AA 1-50, pSer21 Anmelden zum Anzeigen Polyclonal
1 ABIN708119 IF (p) Cy3 Rabbit IgG AA 1-50, pSer21 Anmelden zum Anzeigen Polyclonal
1 ABIN708121 IF (p) Cy5.5 Rabbit IgG AA 1-50, pSer21 Anmelden zum Anzeigen Polyclonal
1 ABIN708120 IF (p) Cy5 Rabbit IgG AA 1-50, pSer21 Anmelden zum Anzeigen Polyclonal
1 ABIN708123 IF (p) FITC Rabbit IgG AA 1-50, pSer21 Anmelden zum Anzeigen Polyclonal
1 ABIN2814063 IF (p) Alexa Fluor 594 Rabbit IgG AA 1-50, pSer21 Anmelden zum Anzeigen Polyclonal
1 ABIN5004109 IF (p) Alexa Fluor 750 Rabbit IgG AA 1-50, pSer21 Anmelden zum Anzeigen Polyclonal
1 ABIN5004108 IF (p) Alexa Fluor 680 Rabbit IgG AA 1-50, pSer21 Anmelden zum Anzeigen Polyclonal

General

Antigen Glycogen Synthase Kinase 3 alpha (GSK3a) Antikörper
Epitop AA 1-50, pSer21
(68), (36), (25), (14), (11), (9), (7), (7), (6), (5), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(310), (161), (133), (7), (7), (6), (4), (4), (3), (1), (1), (1), (1)
Wirt Kaninchen
(217), (119), (3)
Klonalität
Polyklonal
Konjugat Dieser GSK3 alpha Antikörper ist unkonjugiert
(24), (13), (12), (7), (6), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(297), (152), (138), (58), (50), (48), (32), (12), (7), (7), (5), (4), (3), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-GSK3 alpha Antikörper

Target Details GSK3 alpha Anwendungsinformationen Handhabung Bilder
Spezifität This phosphorylation site is homologous to that of Ser21 in Mouse and Rat.
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human GSK3 Alpha around the phosphorylation site of Ser21
Isotyp IgG

Target Details GSK3 alpha

Produktdetails anti-GSK3 alpha Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Gsk3 alpha (GSK3a Antibody Abstract)
Hintergrund

Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth. Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation.

Synonyms: Glycogen synthase kinase-3 alpha, GSK-3 alpha, Serine/threonine-protein kinase GSK3A, GSK3A

Gen-ID 2931
UniProt P49840
Forschungsgebiet Kinases/Phosphatases, Atherosclerosis, Hypertrophy, Wnt, Cardiovascular
Pathways PI3K-Akt Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process

Anwendungsinformationen

Produktdetails anti-GSK3 alpha Antikörper Target Details GSK3 alpha Handhabung Bilder zurück nach oben
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-GSK3 alpha Antikörper Target Details GSK3 alpha Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Bilder

Produktdetails anti-GSK3 alpha Antikörper Target Details GSK3 alpha Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
ELISA image for anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 1-50), (pSer21) antibody (ABIN708116) Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:...
SDS-PAGE (SDS) image for anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 1-50), (pSer21) antibody (ABIN708116) Lane 1: rat heart lysates Lane 2: rat brain lysates probed with Anti phospho-GSK3 Alp...
Immunohistochemistry (IHC) image for anti-Glycogen Synthase Kinase 3 alpha (GSK3a) (AA 1-50), (pSer21) antibody (ABIN708116) Formalin-fixed and paraffin embedded rat brain labeled with Anti-phospho-GSK3 Alpha(S...