anti-Maus AKT Antikörper für Fluorescence Microscopy

Recommended AKT Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Antikörper
  • AKT
  • CWS6
  • PKB
  • PKB-ALPHA
  • PRKBA
  • RAC
  • RAC-ALPHA
  • Akt
  • Rac
  • PKB/Akt
  • PKBalpha
  • beta-actin
  • AKT/PKB
  • AKT1
  • Akt/PKB
  • Akt1
  • CG4006
  • D-Akt
  • DAKT1
  • DAKT1/PKB
  • DAkt
  • DAkt1
  • DPKB
  • DRAC-PK
  • DRAC-PK66
  • DRAC-PK85
  • Dakt
  • Dakt1
  • Dmel\\CG4006
  • Dpkb
  • PKB/AKT
  • PKB/dAKT
  • RacPK
  • akt
  • akt1
  • dAKT
  • dAKT/dPKB
  • dAKT1
  • dAkt
  • dAkt/PKB
  • dAkt1
  • dPKB
  • dakt
  • dakt1
  • l(3)04226
  • l(3)89Bq
  • p-Akt
  • pAkt
  • A
  • ACT5C
  • Ac5C
  • Act
  • Act-5C
  • Act5
  • Act5c
  • Actin
  • Actin/BAP47
  • Actin5C
  • BAP47
  • Bap47
  • CG4027
  • Dmel\\CG4027
  • M32055
  • T11
  • act
  • act 5C
  • act5C
  • actin
  • actin5C
  • anon-EST:fe2D2
  • beta-actin/Bap47
  • cyt5C
  • l(1)G0009
  • l(1)G0010
  • l(1)G0025
  • l(1)G0079
  • l(1)G0117
  • l(1)G0177
  • l(1)G0245
  • l(1)G0330
  • l(1)G0420
  • l(1)G0486
  • ACT-5
  • akt-1
  • pkb
  • v-akt
  • v-akt1
  • xAct
  • ATAKT1
  • F18A8.2
  • F18A8_2
  • K+ transporter 1
  • POTASSIUM TRANSPORTER
  • AKT serine/threonine kinase 1
  • thymoma viral proto-oncogene 1
  • actin beta
  • CG4006 gene product from transcript CG4006-RE
  • Actin 5C
  • v-akt murine thymoma viral oncogene homolog 1 S homeolog
  • v-akt murine thymoma viral oncogene homolog 1
  • K+ transporter 1
  • Serine/threonine-protein kinase akt-1
  • AKT1
  • Akt1
  • ACTB
  • Act5C
  • akt1.S
  • akt1
  • KT1
  • akt-1
Epitop
C-Term
222
131
113
66
56
51
37
36
22
22
21
21
18
16
13
12
12
12
11
11
10
10
9
9
9
8
7
7
7
6
6
6
6
5
5
5
5
5
4
4
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus), Huhn
1256
649
502
63
57
57
46
35
33
30
18
8
8
6
5
5
3
3
3
2
1
1
1
1
1
Wirt
Kaninchen
918
384
12
4
2
Klonalität
Polyklonal
Konjugat
Dieser AKT Antikörper ist unkonjugiert
54
42
40
38
28
25
15
15
10
10
8
6
6
6
6
6
6
6
5
5
5
4
4
2
2
2
2
2
2
2
2
1
1
1
1
Applikation
Fluorescence Microscopy (FM), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
1071
559
479
256
187
175
128
86
67
33
26
15
12
11
11
4
4
3
3
2
2
1
1
1
1
1
1
1
Optionen
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Produktnummer ABIN1043683
$ 139.00
Zzgl. Versandkosten $45.00 und $23.00 Trockeneis
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1043756 FM FRET STED ELISA WB Atto 594 Mouse IgG1 kappa pSer473, Internal Region Anmelden zum Anzeigen 17F6-B11 4
1 ABIN5596660 ELISA FACS FM IHC IP WB Biotin Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN5596665 ELISA FACS FM IHC WB FITC Mouse IgG2a Internal Region Anmelden zum Anzeigen 14E5-A2-B2-H9
1 ABIN5596666 ELISA FACS FM IHC WB FITC Mouse IgG2a Internal Region Anmelden zum Anzeigen 5E5-F5-D7
1 ABIN5596664 ELISA FACS FM IHC WB Biotin Mouse IgG2a Internal Region Anmelden zum Anzeigen 5E5-F5-D7
1 ABIN5596663 ELISA FACS FM IHC WB Biotin Mouse IgG2a Internal Region Anmelden zum Anzeigen 14E5-A2-B2-H9
1 ABIN5596668 ELISA FACS FM IHC WB PE Mouse IgG2a Internal Region Anmelden zum Anzeigen 5E5-F5-D7
1 ABIN5596667 ELISA FACS FM IHC WB PE Mouse IgG2a Internal Region Anmelden zum Anzeigen 14E5-A2-B2-H9
1 ABIN5596661 ELISA FACS FM IHC WB APC Mouse IgG2a Internal Region Anmelden zum Anzeigen 14E5-A2-B2-H9
1 ABIN5596662 ELISA FACS FM IHC WB APC Mouse IgG2a Internal Region Anmelden zum Anzeigen 5E5-F5-D7
1 ABIN5596659 ELISA FACS FM IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

General

Antigen V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) Antikörper
Epitop C-Term
(222), (131), (113), (66), (56), (51), (37), (36), (22), (22), (21), (21), (18), (16), (13), (12), (12), (12), (11), (11), (10), (10), (9), (9), (9), (8), (7), (7), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus), Huhn
(1256), (649), (502), (63), (57), (57), (46), (35), (33), (30), (18), (8), (8), (6), (5), (5), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(918), (384), (12), (4), (2)
Klonalität
Polyklonal
Konjugat Dieser AKT Antikörper ist unkonjugiert
(54), (42), (40), (38), (28), (25), (15), (15), (10), (10), (8), (6), (6), (6), (6), (6), (6), (6), (5), (5), (5), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Applikation Fluorescence Microscopy (FM), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
(1071), (559), (479), (256), (187), (175), (128), (86), (67), (33), (26), (15), (12), (11), (11), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
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Produktdetails anti-AKT Antikörper

Target Details AKT Anwendungsinformationen Handhabung Referenzen für anti-AKT Antikörper (ABIN1043683) Bilder
Spezifität AKT Antibody detects AKT which is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis, (ii) promotion of proliferation. Anti-AKT Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Produktmerkmale AKT Antibody is suitable for western blotting to detect a single band of the expected apparent molecular weight, immunohistochemistry (Formalin-fixed paraffin-embedded sections), immunofluorescence microscopy using paraformaldehyde-fixed primary cardiomyocyte cultures, immunoprecip-itation, transfected cell culture, primary cell culture and ELISA. Researchers should determine optimal titers for applications that are not stated below.
Sterilität Sterile filtered
Immunogen AKT Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide C-R-P-H-F-P-Q-F-S-Y-S-A-S-G-T-A corresponding to the C-terminus (460-480) of human, rat and mouse and chicken AKT proteins conjugated to KLH using maleimide. A residue of cysteine was added to the amino terminal end to facilitate coupling.
Immunogen Type: Peptide

Target Details AKT

Produktdetails anti-AKT Antikörper Anwendungsinformationen Handhabung Referenzen für anti-AKT Antikörper (ABIN1043683) Bilder zurück nach oben
Antigen
Andere Bezeichnung AKT (AKT1 Antibody Abstract)
Hintergrund AKT Antibody is suitable for western blotting to detect a single band of the expected apparent molecular weight, immunohistochemistry (Formalin-fixed paraffin-embedded sections), immunofluorescence microscopy using paraformaldehyde-fixed primary cardiomyocyte cultures, immunoprecip-itation, transfected cell culture, primary cell culture and ELISA. Researchers should determine optimal titers for applications that are not stated below.
Synonyms: RAC-PK-alpha, Protein kinase B, PKB, C-AKT, RAC-alpha serine/threonine-protein kinase, Proto-oncogene c-Akt, AKT1, AKT 1, AKT-1
Gen-ID 207, 62241011
UniProt P31749
Forschungsgebiet Signaling
Pathways PI3K-Akt Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, AMPK Signaling, Interferon-gamma Pathway, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Response to Water Deprivation, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of intrinsic apoptotic Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGFR1 Specific Signals, VEGF Signaling

Anwendungsinformationen

Produktdetails anti-AKT Antikörper Target Details AKT Handhabung Referenzen für anti-AKT Antikörper (ABIN1043683) Bilder zurück nach oben
Applikationshinweise AKT Antibody is suitable for western blotting to detect a single band of the expected apparent molecular weight, immunohistochemistry (Formalin-fixed paraffin-embedded sections), immunofluorescence microscopy using paraformaldehyde-fixed primary cardiomyocyte cultures, immunoprecip-itation, transfected cell culture, primary cell culture and ELISA. Researchers should determine optimal titers for applications that are not stated below.
Kommentare

Gene Name: AKT1

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-AKT Antikörper Target Details AKT Anwendungsinformationen Referenzen für anti-AKT Antikörper (ABIN1043683) Bilder zurück nach oben
Format Liquid
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store vial at 4° C before opening. DO NOT FREEZE. This product is stable at 4° C as an undiluted liquid. Dilute only prior to immediate use. Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity. Expiration date is one (1) year from date of opening.
Haltbarkeit 12 months

Referenzen für anti-AKT Antikörper (ABIN1043683)

Produktdetails anti-AKT Antikörper Target Details AKT Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Matsuda, Takano, Kageyama, Hatakeyama, Shakunaga, Kitajima, Yamazaki, Hattori: "Silencing of caspase-8 and caspase-3 by RNA interference prevents vascular endothelial cell injury in mice with endotoxic shock." in: Cardiovascular research, Vol. 76, Issue 1, pp. 132-40, 2007

Lawlor, Alessi: "PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?" in: Journal of cell science, Vol. 114, Issue Pt 16, pp. 2903-10, 2001

Bilder

Produktdetails anti-AKT Antikörper Target Details AKT Anwendungsinformationen Handhabung Referenzen für anti-AKT Antikörper (ABIN1043683) zurück nach oben
Bilder des Herstellers
Immunofluorescence (IF) image for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (C-Term) antibody (ABIN1043683) Immunofluorescence Microscopy of Rabbit Anti-AKT Antibody. Tissue: neonatal rat cardi...
Immunohistochemistry (IHC) image for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (C-Term) antibody (ABIN1043683) anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (C-Term) antibody (Image 2)
Immunofluorescence (IF) image for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (C-Term) antibody (ABIN1043683) anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (C-Term) antibody (Image 3)
Western Blotting (WB) image for anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (C-Term) antibody (ABIN1043683) anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (C-Term) antibody (Image 4)