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Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2) (Middle Region) Peptid

UBE2D2 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN985812
  • Target Alle UBE2D2 Produkte
    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-UBE2D2 antibody (Catalog #: ARP43010_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
    Synonyme
    E2(17)KB2 Peptide, PUBC1 Peptide, UBC4 Peptide, UBC4/5 Peptide, UBCH5B Peptide, 1500034D03Rik Peptide, Ubc2e Peptide, Ube2d2 Peptide, ubc4 Peptide, ube2d2 Peptide, zgc:55886 Peptide, E217kB Peptide, ubiquitin conjugating enzyme E2 D2 Peptide, ubiquitin-conjugating enzyme E2D 2A Peptide, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) Peptide, ubiquitin-conjugating enzyme E2D 2 Peptide, ubiquitin conjugating enzyme E2 D3 Peptide, UBE2D2 Peptide, Ube2d2a Peptide, ube2d2 Peptide, Ube2d2 Peptide, UBE2D3 Peptide
    Hintergrund
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

    Alias Symbols: E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B

    Protein Interaction Partner: CBL,AMFR,BTRC,CBL,CNOT4,DTX3L,NEDD4,NFKBIA,PJA1,PJA2,RNF11,RNF5,UBE2D2,AMFR,APC11,BARD1,BIRC3,BTRC,CBL,CDKN1B,DDX58,DTX3L,DZIP3,EPS15,FBXL3,FBXO4,FBXO7,FBXW2,ING4,NEDD4,OTUB1,PDZRN3,PJA1,PJA2,POLL,POLM,RAF1,RNF11,RNF2,STAM2,STUB1,TRIM5,UBA6,UBASH3B,UBE3A

    Protein Size: 147
    Molekulargewicht
    17 kDa
    Gen-ID
    7322
    NCBI Accession
    NM_003339, NP_003330
    UniProt
    P62837
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