Exoribonuclease 1 (ERI1) (N-Term) Peptid
ERI1
Reaktivität: Human
Wirt: Synthetic
BP, WB
-
- Target Alle ERI1 Produkte
- ERI1 (Exoribonuclease 1 (ERI1))
- Protein Region
- N-Term
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- SKFITSSASD FSDPVYKEIA ITNGCINRMS KEELRAKLSE FKLETRGVKD
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- ERI1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- ERI1 (Exoribonuclease 1 (ERI1))
- Synonyme
- THEX1 Peptide, thex1 Peptide, zgc:110635 Peptide, hexo Peptide, Eri-1 Peptide, 3'HEXO Peptide, HEXO Peptide, 3'hexo Peptide, 3110010F15Rik Peptide, Thex1 Peptide, eri-1 Peptide, RGD1308378 Peptide, exoribonuclease 1 Peptide, three prime repair exonuclease 1 Peptide, exoribonuclease 1 L homeolog Peptide, 3'-5' exonuclease eri-1 Peptide, ERI1 Peptide, CpipJ_CPIJ003945 Peptide, eri1 Peptide, eri1.L Peptide, Eri1 Peptide, eri-1 Peptide
- Hintergrund
-
RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Alias Symbols: HEXO, THEX1, 3'HEXO
Protein Size: 349 - Molekulargewicht
- 40 kDa
- Gen-ID
- 90459
- NCBI Accession
- NM_153332, NP_699163
- UniProt
- Q8IV48
-
Sie sind hier:
