TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6) (C-Term) Peptid
TAF6
Reaktivität: Human
Wirt: Synthetic
BP, WB, ChIP
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- Target Alle TAF6 Produkte
- TAF6 (TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6))
- Protein Region
- C-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-TAF6 antibody (Catalog #: ARP38653_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TAF6 (TAF6 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 80kDa (TAF6))
- Synonyme
- CG32211 Peptide, CG9348 Peptide, Dmel\\CG32211 Peptide, SR3-4B Peptide, TAF Peptide, TAF6 Peptide, TAF60 Peptide, TAF60/62 Peptide, TAFII60 Peptide, TAFII60(62) Peptide, TAFII62 Peptide, TAF[[II]] Peptide, TAF[[II]]60 Peptide, TAF[[II]]60/62 Peptide, TAF[[II]]62 Peptide, TFIID Peptide, TFIID 62 Peptide, Taf-6 Peptide, Taf60 Peptide, Taf62 Peptide, Taf[[II]]60 Peptide, d60 Peptide, dTAF6 Peptide, dTAF62 Peptide, dTAFII62 Peptide, dTAF[[II]]262 Peptide, dTAF[[II]]60 Peptide, dTAF[[II]]62 Peptide, dmTAF6 Peptide, dme-TAFII60 Peptide, l(3)76BDf Peptide, p62 Peptide, taf6 Peptide, taf60 Peptide, wu:fb83e08 Peptide, wu:fj30b02 Peptide, zgc:92160 Peptide, 80kDa Peptide, AW549759 Peptide, TAF(II)80 Peptide, TAFII70 Peptide, Taf2e Peptide, p80 Peptide, TAF(II)60 Peptide, MGC:8964 Peptide, TAF(II)70 Peptide, TAF2E Peptide, TAFII-70 Peptide, TAFII-80 Peptide, TAFII80 Peptide, TAFII85 Peptide, TBP-associated factor 6 Peptide, TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor Peptide, TATA-box binding protein associated factor 6 Peptide, TATA-box binding protein associated factor 6 L homeolog Peptide, Taf6 Peptide, taf6 Peptide, taf6.L Peptide, TAF6 Peptide
- Hintergrund
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TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF6 is one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1,the largest subunit of TFIID. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Four isoforms have been identified but complete transcripts have been determined for only three isoforms. One of the isoforms has been shown to preclude binding of one of the other TFIID subunits, thereby reducing transcription and initiating signals that trigger apoptosis.
Alias Symbols: DKFZp781E21155, MGC:8964, TAF2E, TAFII70, TAFII80, TAFII85, TAFII-70, TAFII-80, TAF(II)70, TAF(II)80
Protein Interaction Partner: TAF9,CIITA,GTF2E1,RELA,SH3KBP1,TAF1,TAF10,TAF11,TAF12,TAF2,TAF4,TAF5,TAF6,TAF7,TAF8,TAF9,AHR,GTF2A1,GTF2E1,RELA,SH3KBP1,TAF1,TAF12,TAF13,TAF5,TAF9,TBP,TBPL1,TP53
Protein Size: 677 - Molekulargewicht
- 73 kDa
- Gen-ID
- 6878
- NCBI Accession
- NM_005641, NP_005632
- UniProt
- P49848
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