Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) (N-Term) Peptid

Details zu Produkt Nr. ABIN983813, Anbieter: Anmelden zum Anzeigen
Proteinname
  • slc12a1
  • SLC12A1
  • DKFZp469A2020
  • BSC1
  • NKCC2
  • Nkcc2
  • AI788571
  • D630042G03Rik
  • mBSC1
  • urehr3
  • si:ch211-220f12.1
  • solute carrier family 12 (sodium/potassium/chloride transporters), member 1
  • solute carrier family 12 (sodium/potassium/chloride transporter), member 1
  • solute carrier family 12, member 1
  • si:ch211-220f12.1
  • SLC12A1
  • Slc12a1
Protein Region
N-Term
Spezies
Human
1
1
1
1
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Geblockter Antikörper anti-SLC12A1 Antikörper (Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1) (N-Term) (ABIN2776780)
Sequenz NEKKSRGFFN YQASIFAENF GPRFTKGEGF FSVFAIFFPA ATGILAGANI
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-SLC12A1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Hintergrund This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.

Alias Symbols: BSC1, NKCC2

Protein Size: 430
Molekulargewicht 47 kDa
Gen-ID 6557
NCBI Accession NM_000338, NP_000329
UniProt Q8IUN5
Forschungsgebiet Signaling, Metabolism
Applikationshinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.