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Ribosomal Protein L32 (RPL32) (Middle Region) Peptid

RPL32 Reaktivität: Human, Maus Wirt: Synthetic BP, WB
Produktnummer ABIN983196
  • Target Alle RPL32 Produkte
    RPL32 (Ribosomal Protein L32 (RPL32))
    Protein Region
    Middle Region
    Spezies
    Human, Maus
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    MEDTQDLNEQ SVKKTCPEAD VSEPQNSRSM EMQDLASPHA LVGGSDTPGS
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-Eya4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RPL32 (Ribosomal Protein L32 (RPL32))
    Synonyme
    L32 Peptide, AU020185 Peptide, rpL32-3A Peptide, zgc:136952 Peptide, 143250_at Peptide, BcDNA:RH03940 Peptide, CG7939 Peptide, Dmel\\CG7939 Peptide, M(3)99D Peptide, RP-49 Peptide, RP49 Peptide, RPL32 Peptide, Rp-49 Peptide, Rp49 Peptide, Rp49/RpL32 Peptide, Rpl32 Peptide, bs30a02.y1 Peptide, rp49 Peptide, rp49/RpL32 Peptide, ribosomal protein L32 Peptide, 50S ribosomal protein L32 Peptide, rpl32 Peptide, ribosomal protein L32 L homeolog Peptide, Ribosomal protein L32 Peptide, ribosomal protein L32 homolog32 Peptide, RPL32 Peptide, rpl32 Peptide, Rpl32 Peptide, rpl32.L Peptide, RpL32 Peptide
    Hintergrund
    Eya4 is a tyrosine phosphatase that specifically dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph). 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Eya4 promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regulation during organogenesis. It may be involved in development of the eye.

    Alias Symbols: B130023L16Rik

    Protein Interaction Partner: Eya4,Six1,Six2

    Protein Size: 616
    Molekulargewicht
    67 kDa
    Gen-ID
    14051
    NCBI Accession
    NM_010167, NP_034297
    UniProt
    Q9Z191
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