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RING Finger Protein 6 (RNF6) (N-Term) Peptid

RNF6 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN983102
  • Target Alle RNF6 Produkte
    RNF6 (RING Finger Protein 6 (RNF6))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 5
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-RNF6 antibody (Catalog #: ARP43064_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RNF6 (RING Finger Protein 6 (RNF6))
    Synonyme
    1200013I08Rik Peptide, 5730419H05Rik Peptide, AA537053 Peptide, ring finger protein 6 Peptide, ring finger protein (C3H2C3 type) 6 Peptide, RNF6 Peptide, Rnf6 Peptide
    Hintergrund
    RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.

    Alias Symbols: DKFZp686P0776

    Protein Size: 685
    Molekulargewicht
    78 kDa
    Gen-ID
    6049
    NCBI Accession
    NM_005977, NP_005968
    UniProt
    Q9Y252
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