This is a synthetic peptide designed for use in combination with anti-Rgs10 Antibody(ARP42856_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
RGS10
Reaktivität: Human, Maus, Rind (Kuh), Ratte
Wirt: Synthetic
BP
Applikationshinweise
Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Handhabung
Avoid repeated freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
RGS10
(Regulator of G-Protein Signaling 10 (RGS10))
Synonyme
MGC82511 Peptide, RGS10 Peptide, 2310010N19Rik Peptide, regulator of G-protein signaling 10 Peptide, regulator of G-protein signaling 10 L homeolog Peptide, regulator of G protein signaling 10 Peptide, regulator of G-protein signalling 10 Peptide, RGS10 Peptide, rgs10.L Peptide, rgs10 Peptide, Rgs10 Peptide
Hintergrund
Rgs10 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Rgs10 associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)-alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity of Rgs10 on G(z)-alpha is inhibited by palmitoylation of the G-protein.