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Proline Rich 5 (Renal) (PRR5) (C-Term) Peptid

PRR5 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN982285
  • Target Alle PRR5 Produkte
    PRR5 (Proline Rich 5 (Renal) (PRR5))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    SPAPHSGPCP SRLYPTTQPP EQGLDPTRSS LPRSSPENLV DQILESVDSD
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PRR5 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PRR5 (Proline Rich 5 (Renal) (PRR5))
    Synonyme
    AU043908 Peptide, Arhgap8 Peptide, C030017C09Rik Peptide, C78947 Peptide, Protor-1 Peptide, Protor1 Peptide, FLJ20185k Peptide, PP610 Peptide, PROTOR-1 Peptide, PROTOR1 Peptide, pp610 Peptide, protor1 Peptide, protor2 Peptide, proline rich 5 (renal) Peptide, proline rich 5 Peptide, proline rich 5 L homeolog Peptide, Prr5 Peptide, PRR5 Peptide, prr5.L Peptide
    Hintergrund
    This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.

    Alias Symbols: PP610, PROTOR1, PROTOR-1, FLJ20185k

    Protein Size: 293
    Molekulargewicht
    41 kDa
    Gen-ID
    55615
    NCBI Accession
    NM_001017528, NP_056181
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