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Pyruvate Carboxylase (PC) (C-Term) Peptid

PC Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN981417
  • Target Alle PC Produkte
    PC (Pyruvate Carboxylase (PC))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    SLPPLDLQAL EKELVDRHGE EVTPEDVLSA AMYPDVFAHF KDFTATFGPL
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PC Antibody(ARP59606_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PC (Pyruvate Carboxylase (PC))
    Synonyme
    BcDNA Peptide, BcDNA:GH06348 Peptide, Dmel\\CG1516 Peptide, PC Peptide, pyc Peptide, wu:fb82g08 Peptide, wu:fj85g01 Peptide, PCX Peptide, BA4157 Peptide, Pc Peptide, Pcb Peptide, PCB Peptide, Pcx Peptide, Pyruvate carboxylase Peptide, pyruvate carboxylase b Peptide, PYruvate Carboxylase Peptide, pyruvate carboxylase Peptide, pyruvate carboxylase Pyr1 Peptide, PCB Peptide, pcxb Peptide, pyc-1 Peptide, PC Peptide, pyc Peptide, pyr1 Peptide, CNF00650 Peptide, PYC1 Peptide, Ndas_1152 Peptide, Ilyop_2503 Peptide, Calni_0495 Peptide, Ftrac_1004 Peptide, Plabr_3574 Peptide, Sgly_2936 Peptide, Celly_0558 Peptide, Hipma_0131 Peptide, Halhy_1567 Peptide, Mesop_1269 Peptide, Pcx Peptide, Pc Peptide
    Hintergrund
    This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.

    Alias Symbols: PCB

    Protein Interaction Partner: GOT2,MDH2,GOT1,MDH2

    Protein Size: 1178
    Molekulargewicht
    127 kDa
    Gen-ID
    5091
    NCBI Accession
    NM_001040716, NP_001035806
    UniProt
    P11498
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