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Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16) (Middle Region) Peptid

PARP16 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN981363
  • Target Alle PARP16 Produkte
    PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-PARP16 antibody (Catalog #: ARP33752_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
    Synonyme
    PARP16 Peptide, zgc:77744 Peptide, ARTD15 Peptide, C15orf30 Peptide, pART15 Peptide, BC055447 Peptide, C79952 Peptide, PARP-16 Peptide, LRRGT00109 Peptide, RGD1306243 Peptide, poly(ADP-ribose) polymerase family member 16 Peptide, poly(ADP-ribose) polymerase family member 16 L homeolog Peptide, poly (ADP-ribose) polymerase family, member 16 Peptide, PARP16 Peptide, parp16.L Peptide, parp16 Peptide, Parp16 Peptide
    Hintergrund
    Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP16 is a member of poly(ADP-ribose) polymerases (PARPs) family that is encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.

    Alias Symbols: C15orf30, FLJ20509, FLJ25281, pART15

    Protein Size: 323
    Molekulargewicht
    36 kDa
    Gen-ID
    54956
    NCBI Accession
    NM_017851, NP_060321
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