Mannan-Binding Lectin Serine Peptidase 1 (MASP1) (N-Term) Peptid
MASP1
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle MASP1 Produkte
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- Protein Region
- N-Term
- Spezies
- Human
-
Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- PGSFMSITFR SDFSNEERFT GFDAHYMAVD VDECKEREDE ELSCDHYCHN
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-MASP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- MASP1 (Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
- Synonyme
- AW048060 Peptide, CCPII Peptide, Crarf Peptide, Masp1/3 Peptide, 3MC1 Peptide, CRARF Peptide, CRARF1 Peptide, MAP1 Peptide, MASP Peptide, MASP3 Peptide, MAp44 Peptide, PRSS5 Peptide, RaRF Peptide, mannan-binding lectin serine peptidase 1 Peptide, mannan binding lectin serine peptidase 1 Peptide, Masp1 Peptide, MASP1 Peptide
- Hintergrund
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This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway.
Alias Symbols: CRARF, CRARF1, DKFZp686I01199, FLJ26383, MASP, MGC126283, MGC126284, PRSS5, RaRF
Protein Size: 699 - Molekulargewicht
- 28 kDa
- Gen-ID
- 5648
- NCBI Accession
- NM_001879, NP_001870
- UniProt
- P48740
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