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Kringle Containing Transmembrane Protein 1 (KREMEN1) (N-Term) Peptid

KREMEN1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN979111
  • Target Alle KREMEN1 Produkte
    KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
    Protein Region
    N-Term
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-KREMEN1 antibody (Catalog #: ARP44880_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    KREMEN1 (Kringle Containing Transmembrane Protein 1 (KREMEN1))
    Synonyme
    KREMEN1 Peptide, krm1 Peptide, kremen Peptide, kremem1 Peptide, KREMEN Peptide, KRM1 Peptide, AV002070 Peptide, Kremen Peptide, Krm1 Peptide, si:ct737139.1 Peptide, si:dkeyp-7c9.1 Peptide, kringle containing transmembrane protein 1 Peptide, kringle containing transmembrane protein 1 S homeolog Peptide, KREMEN1 Peptide, kremen1 Peptide, Kremen1 Peptide, kremen1.S Peptide
    Hintergrund
    KREMEN1 is a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. It is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains.This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

    Alias Symbols: FLJ31863, KREMEM1, KREMEN, KRM1

    Protein Interaction Partner: DKK1

    Protein Size: 475
    Molekulargewicht
    50 kDa
    Gen-ID
    83999
    NCBI Accession
    NM_001039570, NP_001034659
    UniProt
    Q96MU8
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