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High Mobility Group Box 2 (HMGB2) Peptid

HMGB2 Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN978055
  • Target Alle HMGB2 Produkte
    HMGB2 (High Mobility Group Box 2 (HMGB2))
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-HMGB2 antibody (Catalog #: ARP31939_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    HMGB2 (High Mobility Group Box 2 (HMGB2))
    Synonyme
    HMG2 Peptide, C80539 Peptide, HMG-2 Peptide, Hmg2 Peptide, HIGH MOBILITY GROUP BETA 1 Peptide, HMG BETA 1 Peptide, NFD02 Peptide, NFD2 Peptide, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 02 Peptide, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 2 Peptide, high mobility group B2 Peptide, hmgb2 Peptide, hmgb2l Peptide, im:6909096 Peptide, wu:fa20b02 Peptide, zgc:101854 Peptide, wu:fb22b10 Peptide, wu:fc95d12 Peptide, zgc:123215 Peptide, high mobility group box 2 Peptide, high mobility group box 2 S homeolog Peptide, high mobility group B2 Peptide, high mobility group box 2b Peptide, high mobility group box 2a Peptide, HMGB2 Peptide, Hmgb2 Peptide, hmgb2.S Peptide, hmgb2b Peptide, hmgb2a Peptide
    Hintergrund
    This protein is a member of the non-histone chromosomal high mobility group family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in the DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: HMG2

    Protein Interaction Partner: APEX1,CSNK1A1,GZMA,PGR,POU2F1,POU2F2,POU3F1,POU5F1,PRKDC,RAG1,SET,TP53,AR,CSNK1A1,GZMA,NR3C1,PGR,POU2F2,POU5F1,RAG1,SET

    Protein Size: 209
    Molekulargewicht
    24 kDa
    Gen-ID
    3148
    NCBI Accession
    NM_002129, NP_002120
    UniProt
    P26583
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