Growth Factor Receptor-Bound Protein 2 (GRB2) (N-Term) Peptid
GRB2
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle GRB2 Produkte
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
- Protein Region
- N-Term
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- AKYDFKATAD DELSFKRGDI LKVLNEECDQ NWYKAELNGK DGFIPKNYIE
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-GRB2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
- Synonyme
- GRB2 Peptide, grb2 Peptide, AA408164 Peptide, Ash Peptide, ASH Peptide, EGFRBP-GRB2 Peptide, Grb3-3 Peptide, MST084 Peptide, MSTP084 Peptide, NCKAP2 Peptide, wu:fb18e12 Peptide, wu:fb34e06 Peptide, zgc:73077 Peptide, growth factor receptor bound protein 2 Peptide, growth factor receptor-bound protein 2 Peptide, growth factor receptor-bound protein 2b Peptide, GRB2 Peptide, grb2 Peptide, Grb2 Peptide, grb2b Peptide
- Hintergrund
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The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2
Protein Interaction Partner: ADRB1,BCR,BCR,CBL,CHRM4,DRD3,DRD4,DRD4,DRD4,EGFR,EGFR,FASLG,HCVgp1,HTT,KHDRBS1,KIT,KIT,MAP4K1,PAK1,PDE4D,PTK2,PTPN11,RHOU,SH3KBP1,SHC1,SHC1,SOCS1,SOS1,USP6NL,VAV1,ABL1,ADA,ADAM12,ADAM15,ADRB1,ADRB2,ALOX5,ANXA2,APP,AXL,BCAR1,BCL2A1,BCR,BLNK,CALD1,CBLB,CBLC
Protein Size: 217 - Molekulargewicht
- 24 kDa
- Gen-ID
- 2885
- NCBI Accession
- NM_002086, NP_002077
- UniProt
- P62993
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