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Fucosidase, alpha-L- 1, Tissue (FUCA1) Peptid

FUCA1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN977137
  • Target Alle FUCA1 Produkte
    FUCA1 (Fucosidase, alpha-L- 1, Tissue (FUCA1))
    Spezies
    Human
    Quelle
    • 3
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-FUCA1 antibody (Catalog #: ARP54293_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FUCA1 (Fucosidase, alpha-L- 1, Tissue (FUCA1))
    Synonyme
    FUCA Peptide, FUCA1 Peptide, 0610006A03Rik Peptide, 9530055J05Rik Peptide, Afuc Peptide, Fuca Peptide, fuca Peptide, fuca1 Peptide, ATFUC1 Peptide, F24D13.11 Peptide, F24D13_11 Peptide, alpha-L-fucosidase 1 Peptide, wu:fb02a09 Peptide, zgc:101116 Peptide, alpha-L-fucosidase 1 Peptide, fucosidase, alpha-L- 1, tissue Peptide, alpha-L-fucosidase 1 L homeolog Peptide, alpha-L-fucosidase 1, tandem duplicate 2 Peptide, FUCA1 Peptide, Fuca1 Peptide, fuca1.L Peptide, fuca1 Peptide, FUC1 Peptide, LOC9317020 Peptide, LOC100285202 Peptide, fuca1.2 Peptide
    Hintergrund
    Alpha-L-fucosidase (EC 3.2.1.51) is a lysosomal enzyme involved in the degradation of fucose-containing glycoproteins and glycolipids. At least 2 separate polymorphic alpha-L-fucosidases are recognized in man: that in tissues, FUCA1, which is deficient in fucosidosis, and that in plasma, FUCA2. Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective alpha-L-fucosidase with accumulation of fucose in the tissues. Different phenotypes include clinical features such as neurologic deterioration, growth retardation, visceromegaly, and seizures in a severe early form, coarse facial features, angiokeratoma corporis diffusum, spasticity and delayed psychomotor development in a longer surviving form, and an unusual spondylometaphyseoepiphyseal dysplasia in yet another form.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: FUCA

    Protein Interaction Partner: MARK2,USP21

    Protein Size: 466
    Molekulargewicht
    54 kDa
    Gen-ID
    2517
    NCBI Accession
    NM_000147, NP_000138
    UniProt
    P04066
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