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Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8) (C-Term) Peptid

FGF8 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN976837
  • Target Alle FGF8 Produkte
    FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
    Protein Region
    C-Term
    Spezies
    Human
    Quelle
    • 4
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    EGWYMAFTRK GRPRKGSKTR QHQREVHFMK RLPRGHHTTE QSLRFEFLNY
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-FGF8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
    Synonyme
    Aigf Peptide, Fgf-8 Peptide, AIGF Peptide, FGF-8 Peptide, HBGF-8 Peptide, HH6 Peptide, KAL6 Peptide, fibroblast growth factor 8 Peptide, Fgf8 Peptide, FGF8 Peptide
    Hintergrund
    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.

    Alias Symbols: AIGF, HBGF-8, KAL6, MGC149376, FGF-8

    Protein Interaction Partner: AR,FGFR1,FGFR2,FGFR3,FGFR4,FGFR3

    Protein Size: 215
    Molekulargewicht
    22 kDa
    Gen-ID
    2253
    NCBI Accession
    NM_006119, NP_006110
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