Farnesyl Diphosphate Synthase (FDPS) (C-Term) Peptid
FDPS
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle FDPS Produkte
- FDPS (Farnesyl Diphosphate Synthase (FDPS))
- Protein Region
- C-Term
- Spezies
- Human
- Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Sequenz
- VKYKTAFYSF YLPIAAAMYM AGIDGEKEHA NAKKILLEMG EFFQIQDDYL
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-FDPS Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
-
- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- FDPS (Farnesyl Diphosphate Synthase (FDPS))
- Synonyme
- CG12389 Peptide, DmFPPS Peptide, DmFPPSase Peptide, DmFPS Peptide, Dmel\\CG12389 Peptide, FPS Peptide, fpps Peptide, fps Peptide, l(2)k06103 Peptide, v(2)k03514 Peptide, NCU01175.1 Peptide, 16.m00760 Peptide, DDBDRAFT_0206220 Peptide, DDBDRAFT_0215017 Peptide, DDB_0206220 Peptide, DDB_0215017 Peptide, FPPS Peptide, Ac2-125 Peptide, (2E Peptide, 6030492I17Rik Peptide, AI256750 Peptide, Fdpsl1 Peptide, mKIAA1293 Peptide, Farnesyl pyrophosphate synthase Peptide, farnesyl diphosphate synthase Peptide, farnesyl diphosphate synthase L homeolog Peptide, farnesyl pyrophosphate synthase Peptide, farnesyl pyrophosphate synthetase Peptide, farnesyl-pyrophosphate synthetase Peptide, FDP synthase Peptide, Farnesyl pyrophosphate synthetase Peptide, farnesyl diphosphate synthetase Peptide, farnesyl pyrophosphate synthase 1 Peptide, Fpps Peptide, fdps Peptide, fdps.L Peptide, MGG_08649 Peptide, TP03_0857 Peptide, Tb09.160.4300 Peptide, fpp Peptide, BBOV_I000120 Peptide, fps Peptide, fpps Peptide, FDPS Peptide, Fdps Peptide, fps1 Peptide
- Hintergrund
-
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FPPS, FPS
Protein Interaction Partner: ATXN1,FGFR1,FGFR1,UBC
Protein Size: 353 - Molekulargewicht
- 38 kDa
- Gen-ID
- 2224
- NCBI Accession
- NM_001135822, NP_001129294
- UniProt
- Q8WMY2
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