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F-Box Protein 8 (FBXO8) (Middle Region) Peptid

FBXO8 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN976762
  • Target Alle FBXO8 Produkte
    FBXO8 (F-Box Protein 8 (FBXO8))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 1
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-FBXO8 antibody (Catalog #: ARP54862_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FBXO8 (F-Box Protein 8 (FBXO8))
    Synonyme
    FBXO8 Peptide, T24I21.22 Peptide, T24I21_22 Peptide, zgc:136842 Peptide, FBS Peptide, FBX8 Peptide, Fbx8 Peptide, F-box protein 8 Peptide, F-box and associated interaction domains-containing protein Peptide, F-box protein 8 L homeolog Peptide, FBXO8 Peptide, fbxo8 Peptide, AT2G16810 Peptide, fbxo8.L Peptide, Fbxo8 Peptide
    Hintergrund
    FBXO8 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO8 belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.

    Alias Symbols: DC10, FBS, FBX8

    Protein Interaction Partner: SKP1

    Protein Size: 319
    Molekulargewicht
    37 kDa
    Gen-ID
    26269
    NCBI Accession
    NM_012180, NP_036312
    UniProt
    Q9NRD0
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