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Fas (TNFRSF6)-Associated Via Death Domain (FADD) Peptid

FADD Reaktivität: Human Wirt: Synthetic BP, WB, IHC
Produktnummer ABIN976568
  • Target Alle FADD Produkte
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Spezies
    Human
    Quelle
    • 6
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti-FADD antibody (Catalog #: AVARP01012_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Aufreinigung
    Purified
  • Applikationshinweise
    Each Investigator should determine their own optimal working dilution for specific applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Konzentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Synonyme
    MORT1 Peptide, Mort1/FADD Peptide, Mort1 Peptide, TNFRSF6 Peptide, adaptor Peptide, fadd Peptide, mort1 Peptide, xfadd Peptide, Fas associated via death domain Peptide, Fas (TNFRSF6)-associated via death domain Peptide, Fas associated via death domain S homeolog Peptide, Fas (tnfrsf6)-associated via death domain Peptide, FADD Peptide, Fadd Peptide, fadd.S Peptide, fadd Peptide
    Hintergrund
    The protein encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade.

    Alias Symbols: GIG3, MORT1

    Protein Interaction Partner: CASP8,CASP8,CFLAR,CFLAR,FAS,FAS,NOL3,TRADD,TRADD,TRADD,ABCA1,ANK3,CASP10,CASP8,CASP8AP2,CFLAR,CSNK1A1,DAP3,DAPK1,DDX24,DEDD,EDA2R,FAF1,FAS,FASLG,HIPK3,IKBKG,IRAK1,LRDD,LRRCC1,MBD4,MOBKL3,MYD88,NACA,NOL3,PEA15,PRKCZ,PTPN13,RALBP1,RAP1A,RIPK1,RYBP,STAT1,TNFRSF10A,TNFRSF10B,TRADD,TRAF2,XPO5,ABCA1,ARHGDIA,BID,CASP10,CASP8,CASP8AP2,CFLAR,DAP3,DAPK1,DEDD,EZR,FAS,FASLG,HIPK3,LRDD,MAPK8,MBD4,MOBKL3,MSN,NACA,NOL3,PEA15,PRKCZ,RHOA,RIPK1,RYBP,SUMO1,TNFRSF10A,TNFRSF10B,TNFRSF1A,TRADD

    Protein Size: 208
    Molekulargewicht
    23 kDa
    Gen-ID
    8772
    NCBI Accession
    NM_003824, NP_003815
    UniProt
    Q13158
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