Amyloid beta (A4) Precursor Protein (APP) (Middle Region) Peptid

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Proteinname
  • AAA
  • ABETA
  • ABPP
  • AD1
  • APPI
  • CTFgamma
  • CVAP
  • PN-II
  • PN2
  • aaa
  • abeta
  • abpp
  • ad1
  • appi
  • ctfgamma
  • cvap
  • pn2
  • APP
  • APP-like
  • APPL
  • Abeta
  • BcDNA:GH04413
  • CG7727
  • Dmel\\CG7727
  • EG:65F1.5
  • appl
  • Abpp
  • Adap
  • Ag
  • Cvap
  • E030013M08Rik
  • betaApp
  • app
  • wu:fj34d10
  • wu:fk65e12
  • zgc:85740
  • amyloid beta precursor protein
  • amyloid beta (A4) precursor protein
  • beta amyloid protein precursor-like
  • amyloid beta (A4) precursor protein a
  • amyloid beta precursor protein L homeolog
  • APP
  • app
  • Appl
  • App
  • appa
  • app.L
Protein Region
Middle Region
Spezies
Human
19
6
4
3
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Geblockter Antikörper anti-APP Antikörper (Amyloid beta (A4) Precursor Protein) (Middle Region) (ABIN2777739)
Produktmerkmale This is a synthetic peptide designed for use in combination with anti-APP antibody (Catalog #: ARP33075_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Hintergrund APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Alias Symbols: AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2, PN-II

Protein Interaction Partner: NAE1,TGFB1,TGFB2,APBA1,APP,HTRA2,PSEN1,PSEN1,PSEN1,PSEN2,APBA1,MAPK8IP1,PSEN1,PSEN1,ABL1,ACHE,APBA1,APBA2,APBA3,APBB1,APBB2,APBB3,APOE,APPBP2,BACE1,BACE2,BCAP31,BGN,BLMH,CALR,CASP3,CASP4,CASP6,CASP8,CAV1,CDK5,CHRNA7,CLU,COL1A2,COL25A1,COL4A1,COL4A2,COL4A3,COL4A5,COL4A6,CRYAB,CTSD,DAB1,EPB41,F12,FBLN1,FLOT1,GAPDH,GPC1,GRB2,GSK3B,GSN,HADHB,HMOX2,HSD17B10,HSPG2,HTRA2,IDE,ITM2B,KAT5,KLC1,KNG1,LAMA1,LDLRAP1,LRP1,LRP1B,MAPK8IP1,MAPK8IP2,NAE1,NCSTN,NECAB3,NF1,NID1,NUMB,NUMBL,PIN1,PPID,PRSS2,PRSS3,PSEN1,PSEN2,SERPINA3,SHC1,SHC3,SNCA,SNCB,SPON1,TGFB1,TGFB2,TM2D1,TP53BP2,ACHE,APBA1,APBA2,APBA3,APBB1,APBB2,APBB3,APPBP2,Apbb1,Apbb1,BGN,BLMH,CALR,CAV1,CLSTN1,COL25A1,DAB1,DAB2,FBLN1,GSN,HGS,HSD17B10,KLC1,NAE1,NCSTN,SHC1,SNCA,SNCB

Protein Size: 770
Molekulargewicht 85 kDa
Gen-ID 351
NCBI Accession NM_000484, NP_000475
UniProt P05067
Forschungsgebiet Signaling
Applikationshinweise Each Investigator should determine their own optimal working dilution for specific applications.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.