Amyloid beta (A4) Precursor Protein (APP) (Middle Region) Peptid
APP
Reaktivität: Human
Wirt: Synthetic
BP, WB
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- Target Alle APP Produkte
- APP (Amyloid beta (A4) Precursor Protein (APP))
- Protein Region
- Middle Region
- Spezies
- Human
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Quelle
- Synthetic
- Applikation
- Blocking Peptide (BP), Western Blotting (WB)
- Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-APP antibody (Catalog #: ARP33074_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Aufreinigung
- Purified
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Konzentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- APP (Amyloid beta (A4) Precursor Protein (APP))
- Synonyme
- AAA Peptide, ABETA Peptide, ABPP Peptide, AD1 Peptide, APPI Peptide, CTFgamma Peptide, CVAP Peptide, PN-II Peptide, PN2 Peptide, aaa Peptide, abeta Peptide, abpp Peptide, ad1 Peptide, appi Peptide, ctfgamma Peptide, cvap Peptide, pn2 Peptide, APP Peptide, APP-like Peptide, APPL Peptide, Abeta Peptide, BcDNA:GH04413 Peptide, CG7727 Peptide, Dmel\\CG7727 Peptide, EG:65F1.5 Peptide, appl Peptide, Abpp Peptide, Adap Peptide, Ag Peptide, Cvap Peptide, E030013M08Rik Peptide, betaApp Peptide, app Peptide, wu:fj34d10 Peptide, wu:fk65e12 Peptide, zgc:85740 Peptide, amyloid beta precursor protein Peptide, amyloid beta (A4) precursor protein Peptide, beta amyloid protein precursor-like Peptide, amyloid beta (A4) precursor protein a Peptide, amyloid beta precursor protein L homeolog Peptide, APP Peptide, app Peptide, Appl Peptide, App Peptide, appa Peptide, app.L Peptide
- Hintergrund
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APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Alias Symbols: AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN2, PN-II
Protein Interaction Partner: NAE1,TGFB1,TGFB2,APBA1,APP,HTRA2,PSEN1,PSEN1,PSEN1,PSEN2,APBA1,MAPK8IP1,PSEN1,PSEN1,ABL1,ACHE,APBA1,APBA2,APBA3,APBB1,APBB2,APBB3,APOE,APPBP2,BACE1,BACE2,BCAP31,BGN,BLMH,CALR,CASP3,CASP4,CASP6,CASP8,CAV1,CDK5,CHRNA7,CLU,COL1A2,COL25A1,COL4A1,COL4A2,COL4A3,COL4A5,COL4A6,CRYAB,CTSD,DAB1,EPB41,F12,FBLN1,FLOT1,GAPDH,GPC1,GRB2,GSK3B,GSN,HADHB,HMOX2,HSD17B10,HSPG2,HTRA2,IDE,ITM2B,KAT5,KLC1,KNG1,LAMA1,LDLRAP1,LRP1,LRP1B,MAPK8IP1,MAPK8IP2,NAE1,NCSTN,NECAB3,NF1,NID1,NUMB,NUMBL,PIN1,PPID,PRSS2,PRSS3,PSEN1,PSEN2,SERPINA3,SHC1,SHC3,SNCA,SNCB,SPON1,TGFB1,TGFB2,TM2D1,TP53BP2,ACHE,APBA1,APBA2,APBA3,APBB1,APBB2,APBB3,APPBP2,Apbb1,Apbb1,BGN,BLMH,CALR,CAV1,CLSTN1,COL25A1,DAB1,DAB2,FBLN1,GSN,HGS,HSD17B10,KLC1,NAE1,NCSTN,SHC1,SNCA,SNCB
Protein Size: 695 - Molekulargewicht
- 77 kDa
- Gen-ID
- 351
- NCBI Accession
- NM_201414, NP_958817
- UniProt
- P05067
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