This is a synthetic peptide designed for use in combination with anti-RNASEH2C Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Lagerung
-20 °C
Informationen zur Lagerung
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Target
RNASEH2C
(Ribonuclease H2, Subunit C (RNASEH2C))
Synonyme
AGS3 Peptide, AYP1 Peptide, 1500026D16Rik Peptide, ribonuclease H2 subunit C Peptide, ribonuclease H2, subunit C Peptide, RNASEH2C Peptide, Rnaseh2c Peptide
Hintergrund
This gene encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene.