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Interferon Induced with Helicase C Domain 1 (IFIH1) (Middle Region) Peptid

IFIH1 Reaktivität: Human Wirt: Synthetic BP, WB
Produktnummer ABIN5513096
  • Target Alle IFIH1 Produkte
    IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
    Protein Region
    Middle Region
    Spezies
    Human
    Quelle
    • 7
    Synthetic
    Applikation
    Blocking Peptide (BP), Western Blotting (WB)
    Sequenz
    PYQMEVAQPA LEGKNIIICL PTGSGKTRVA VYIAKDHLDK KKKASEPGKV IV
    Produktmerkmale
    This is a synthetic peptide designed for use in combination with anti- IFIH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
    Synonyme
    MDA5 Peptide, Hlcd Peptide, IDDM19 Peptide, MDA-5 Peptide, RLR-2 Peptide, 9130009C22Rik Peptide, Helicard Peptide, RGD1560496 Peptide, interferon induced with helicase C domain 1 Peptide, IFIH1 Peptide, Ifih1 Peptide
    Hintergrund
    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19.

    Alias Symbols: AGS7, Hlcd, MDA5, MDA-5, RLR-2, IDDM19, SGMRT1

    Protein Size: 1025
    Gen-ID
    64135
    NCBI Accession
    NM_022168, NP_071451
    UniProt
    Q9BYX4
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