GRB2-Related Adaptor Protein (GRAP) (N-Term) Peptid

Details zu Produkt Nr. ABIN2184413, Anbieter: Anmelden zum Anzeigen
Proteinname
  • 8430435N19Rik
  • BB233594
  • GRAP
  • grap
  • zgc:110202
  • MGC109892
  • si:dkeyp-9d4.1
  • Grap
  • GRB2-related adaptor protein
  • GRB2-related adapter protein
  • GRB2-related adaptor protein a
  • GRB2-related adaptor protein b
  • GRAP
  • Grap
  • LOC489534
  • grapa
  • grapb
  • LOC100727005
Protein Region
N-Term
Spezies
Human
3
2
1
1
1
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Geblockter Antikörper anti-GRAP Antikörper (GRB2-Related Adaptor Protein) (N-Term) (ABIN2791566)
Sequenz SDELAFNKGD TLKILNMEDD QNWYKAELRG VEGFIPKNYI RVKPHPWYSG
Produktmerkmale This is a synthetic peptide designed for use in combination with antiGRAP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Reinigung Purified
Hintergrund This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligandactivated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCRABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its Nterminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.

Alias Symbols: -

Protein Size: 217
Molekulargewicht 25 kDa
Gen-ID 10750
NCBI Accession NM_006613, NP_006604
UniProt Q13588
Forschungsgebiet Signaling
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Konzentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handhabung Avoid repeat freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For longer periods of storage, store at 20C. Avoid repeat freezethaw cycles.