anti-Kaninchen PCSK1 Antikörper für Western Blotting

Recommended PCSK1 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) Antikörper
  • BMIQ12
  • NEC1
  • PC1
  • PC3
  • SPC3
  • Nec-1
  • Nec1
  • Phpp-1
  • BDP
  • PC1/3
  • proprotein convertase subtilisin/kexin type 1
  • prohormone convertase 1
  • PCSK1
  • Pcsk1
  • pcsk1
  • PC1B
Epitop
Middle Region
7
3
3
2
2
2
2
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
26
14
11
6
2
2
1
1
1
1
1
Wirt
Kaninchen
19
12
Klonalität
Polyklonal
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
29
12
9
9
8
2
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2778153
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2626610 IHC (p) WB Rabbit IgG AA 726-740 Anmelden zum Anzeigen Polyclonal

General

Antigen Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) Antikörper
Epitop Middle Region
(7), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
(26), (14), (11), (6), (2), (2), (1), (1), (1), (1), (1)
Wirt Kaninchen
(19), (12)
Klonalität
Polyklonal
Applikation Immunohistochemistry (IHC), Western Blotting (WB)
(29), (12), (9), (9), (8), (2), (2), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-PCSK1 Antikörper

Target Details PCSK1 Anwendungsinformationen Handhabung Referenzen für anti-PCSK1 Antikörper (ABIN2778153) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN981479.
Sequenz QSPKKSPSAK LNIPYENFYE ALEKLNKPSQ LKDSEDSLYN DYVDVFYNTK
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against PCSK1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human PCSK1

Target Details PCSK1

Produktdetails anti-PCSK1 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-PCSK1 Antikörper (ABIN2778153) Bilder zurück nach oben
Antigen
Andere Bezeichnung PCSK1 (PCSK1 Antibody Abstract)
Hintergrund PCSK1 is involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin and insulin.The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. The use of alternate polyadenylation sites has been found for this gene. Multiple alternatively spliced transcript variants have been described for this gene but their full length nature is not known. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NEC1, PC1, PC3, SPC3, BMIQ12
Protein Interaction Partner: env, AFF1, PCSK1N, REN, PMCH, IAPP, PTK2, CTNNB1,
Protein Size: 753
Molekulargewicht 71 kDa
Gen-ID 5122
NCBI Accession NM_000439, NP_000430
UniProt P29120
Pathways Peptide Hormone Metabolism

Anwendungsinformationen

Produktdetails anti-PCSK1 Antikörper Target Details PCSK1 Handhabung Referenzen für anti-PCSK1 Antikörper (ABIN2778153) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 753 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-PCSK1 Antikörper Target Details PCSK1 Anwendungsinformationen Referenzen für anti-PCSK1 Antikörper (ABIN2778153) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PCSK1 Antikörper (ABIN2778153)

Produktdetails anti-PCSK1 Antikörper Target Details PCSK1 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Rehfeld, Bundgaard, Hannibal, Zhu, Norrbom, Steiner, Friis-Hansen: "The cell-specific pattern of cholecystokinin peptides in endocrine cells versus neurons is governed by the expression of prohormone convertases 1/3, 2, and 5/6." in: Endocrinology, Vol. 149, Issue 4, pp. 1600-8, 2008

Bilder

Produktdetails anti-PCSK1 Antikörper Target Details PCSK1 Anwendungsinformationen Handhabung Referenzen für anti-PCSK1 Antikörper (ABIN2778153) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Proprotein Convertase Subtilisin/kexin Type 1 (PCSK1) (Middle Region) antibody (ABIN2778153) Immunohistochemistry with Pancreas tissue at an antibody concentration of 5µg/ml usin...