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Human Polyclonal EXOC7 Primary Antibody für IHC (p), IHC - ABIN409080
Xu, Shen, Li, Pacheco-Rodriguez, Moss, Vaughan: Interaction of BIG2, a brefeldin A-inhibited guanine nucleotide-exchange protein, with exocyst protein Exo70. in Proceedings of the National Academy of Sciences of the United States of America 2005
EXO70H4-dependent trichome cell wall hardening is a unique phenomenon, which may be conserved among a variety of the land plants.
PUB22-mediated degradation of Exo70B2 contributes to the attenuation of PAMP (zeige ADM Antikörper)-induced signaling.
the results identify Exo70 as a novel transcriptional target of HNF4alpha (zeige HNF4A Antikörper) to promote cell cycle progression in hepatoma, thus provide a basis for the development of therapeutic strategies for hepatocellular carcinoma.
the expression of CTTN (zeige CTTN Antikörper), Exo70 and MMP-9 (zeige MMP9 Antikörper) in HCC (zeige FAM126A Antikörper) cells was detected and their relations with the ability of migration and invasion of hepatoma carcinoma cells were evaluated
GIV (zeige CCDC88A Antikörper) directly and constitutively binds the exocyst complex subunit Exo-70 and also associates with GLUT4 (zeige SLC2A4 Antikörper)-storage vesicles (GSVs) exclusively upon insulin (zeige INS Antikörper) stimulation.
We show that Exo70, a component of the exocyst complex, undergoes isoform switching mediated by ESRP1 (zeige ESRP1 Antikörper), a pre-mRNA splicing factor (zeige SNRPB Antikörper) that regulates epithelial mesenchymal transition.
Exo70 thus represents a membrane-bending protein that may couple actin dynamics and plasma membrane remodeling for morphogenesis.
Exo70 is involved in caveolin-1 (zeige CAV1 Antikörper) recycling to the plasma membrane during re-adhesion of the cells to the substratum.
Exocyst component Exo70 is a direct substrate of the extracellular signal-regulated kinases 1/2, their phosphorylation enhances the binding of Exo70 to other exocyst components and promotes the assembly of the exocyst complex.
PIPKIgamma and phosphatidyl inositol phosphate pools at nascent E-cadherin (zeige CDH1 Antikörper) contacts cue Exo70 targeting and orient the tethering of exocyst-associated E-cadherin (zeige CDH1 Antikörper)
BIG2 (zeige ARFGEF2 Antikörper) and Exo70 interact in trans-Golgi network and centrosomes, as well as in exocyst structures or complexes that move along microtubules to the plasma membrane.
The exocyst complex is required for targeting of Glut4 (zeige SLC2A4 Antikörper) to the plasma membrane by insulin (zeige INS Antikörper)
Exo70 mediates AMPA (zeige GRIA3 Antikörper) receptor insertion at the postsynaptic membrane, but it does not participate in receptor targeting.
Given the low level of sequence conservation within Exo70, this structure provides new insights into our understanding of many species-specific functions of the exocyst
Results show that Snapin (zeige SNAPIN Antikörper) interacts with the exocyst Exo70 and plays a modulatory role in GLUT4 (zeige SLC2A4 Antikörper) vesicle trafficking.
fusion of GLUT4 (zeige SLC2A4 Antikörper) vesicles is the rate-limiting step regulated by insulin (zeige INS Antikörper) downstream of Exo70-mediated tethering
The protein encoded by this gene is a component of the exocyst complex. The exocyst complex plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. The encoded protein is required for assembly of the exocyst complex and docking of the complex to the plasma membrane. The encoded protein may also play a role in pre-mRNA splicing through interactions with pre-mRNA-processing factor 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4.
, exocyst complex component 7
, Exocyst complex component 7
, exocyst complex component Exo70
, exocyst component protein 70 kDa homolog