anti-Ratte (Rattus) p53 Antikörper für Radioimmunoassay

Recommended p53 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Protein P53 (TP53) Antikörper
  • tp53
  • p53
  • TP53
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • TpMs
  • BCC7
  • LFS1
  • P53
  • TRP53
  • Trp53
  • Xp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • cellular tumor antigen p53
  • tumor protein p53
  • tumor supressor p53
  • p53 tumor suppressor
  • transformation related protein 53
  • transformation related protein 53, pseudogene
  • trichoplein, keratin filament binding
  • Wistar clone pR53P1 p53 pseudogene
  • CpipJ_CPIJ002758
  • TP53
  • tp53
  • P53
  • Trp53
  • Trp53-ps
  • TCHP
  • Tp53
  • p53-ps
Epitop
AA 46-53
170
118
84
83
69
65
55
55
53
53
49
47
46
45
40
32
31
31
25
23
23
22
20
18
17
16
15
15
15
15
15
14
11
10
10
9
9
9
8
8
7
7
7
7
6
6
6
6
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Ratte (Rattus)
2329
514
418
186
127
94
85
82
34
23
20
18
17
16
15
14
6
4
4
4
4
3
3
3
2
2
1
1
Wirt
Maus
1322
1112
7
3
3
1
1
1
Klonalität
Monoklonal
Konjugat
Dieser p53 Antikörper ist unkonjugiert
78
76
63
53
45
44
30
30
25
25
25
24
24
24
24
23
23
23
21
20
19
18
14
14
14
14
14
12
7
5
5
5
5
5
5
5
5
4
3
2
2
2
Applikation
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Radioimmunoassay (RIA), Western Blotting (WB)
1856
746
718
715
614
595
423
340
299
179
71
41
32
31
18
17
15
14
13
9
9
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Hersteller
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Produktnummer ABIN5550996
357,50 €
Zzgl. Versandkosten 20,00 € und MWSt

Ähnliche anti-p53 Antikörper

Applikation / Reaktivität Ratte (Rattus)
Chromatin Immunoprecipitation (ChIP) 1 Antikörper
Cytometry by Time of Flight (CyTOF) 4 Antikörper
ELISA 128 Antikörper
Enzyme Immunoassay (EIA) 2 Antikörper
Flow Cytometry (FACS) 72 Antikörper
Gel Shift (GS) 3 Antikörper
Immunochromatography (IC) 7 Antikörper
Immunocytochemistry (ICC) 64 Antikörper
Immunofluorescence (IF) 116 Antikörper
Immunofluorescence (Cultured Cells) (IF (cc)) 13 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 13 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 73 Antikörper
Immunohistochemistry (IHC) 104 Antikörper
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antikörper
Immunohistochemistry (Frozen Sections) (IHC (fro)) 59 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 78 Antikörper
Immunoprecipitation (IP) 68 Antikörper
Intracellular Staining (ICS) 1 Antikörper
Radioimmunoassay (RIA) 1 Antikörper
Western Blotting (WB) 298 Antikörper

General

Antigen Tumor Protein P53 (TP53) Antikörper
Epitop AA 46-53
(170), (118), (84), (83), (69), (65), (55), (55), (53), (53), (49), (47), (46), (45), (40), (32), (31), (31), (25), (23), (23), (22), (20), (18), (17), (16), (15), (15), (15), (15), (15), (14), (11), (10), (10), (9), (9), (9), (8), (8), (7), (7), (7), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Ratte (Rattus)
(2329), (514), (418), (186), (127), (94), (85), (82), (34), (23), (20), (18), (17), (16), (15), (14), (6), (4), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1)
Wirt Maus
(1322), (1112), (7), (3), (3), (1), (1), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser p53 Antikörper ist unkonjugiert
(78), (76), (63), (53), (45), (44), (30), (30), (25), (25), (25), (24), (24), (24), (24), (23), (23), (23), (21), (20), (19), (18), (14), (14), (14), (14), (14), (12), (7), (5), (5), (5), (5), (5), (5), (5), (5), (4), (3), (2), (2), (2)
Applikation Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Radioimmunoassay (RIA), Western Blotting (WB)
(1856), (746), (718), (715), (614), (595), (423), (340), (299), (179), (71), (41), (32), (31), (18), (17), (15), (14), (13), (9), (9), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-p53 Antikörper

Target Details p53 Anwendungsinformationen Handhabung Bilder
Spezifität Detects ~53 kDa.
Cellular Localization: Cytoplasmic, Endoplasmic reticulum and Nuclear.
Produktmerkmale Synonyms: Cellular tumor antigen p53, Tumor suppressor p53, Phosphoprotein p53, NY-CO-13
Reinigung Protein A Chromatography.
Immunogen Fusion protein (Human), amino acids 46-53Remarks: Mol. Wt. of Antigen: 53 kDa
Klon Pab 1801
Isotyp IgG1

Target Details p53

Produktdetails anti-p53 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung p53 (TP53) (TP53 Antibody Abstract)
Hintergrund The p53 protein (tumor protein 53 or TP53) is a DNA-binding cell cycle-regulating transcription factor that governs cell division and the fine balance between cell death and cell survival (1). P53 plays a critical role in tumor suppression and hence it is often described as "the guardian of the genome", "the guardian angel gene", or the "master watchman." This also refers to its role in conserving stability by preventing genome mutation (2). Defects in p53 are linked to >50 % of human cancers, and restoring p53 function to these cancer cells can induce growth arrest and apoptosis (3). When p53 has been damaged, it can also lead to autoimmune disorders (4, 5).Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
Gen-ID 7157
UniProt P04637
Pathways p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie

Anwendungsinformationen

Produktdetails anti-p53 Antikörper Target Details p53 Handhabung Bilder zurück nach oben
Applikationshinweise ELISA. Immunoprecipiation: Use at 10 μg/mL of Lysate. Flow Cytometry. Radioimmunoassay. Immunohistochemistry on Frozen Sections: 1/100-1/250. Immunohistochemistry on Paraffin Sections: 2-4 μg/mL for 30 min at RT, staining offormalin/paraffin tissues REQUIRES boiling tissue sections in 10 mM citrate buffer, pH 6.0,for 10-20 min followed by cooling at RT for 20 min. Western blot: 1/1000-1/2000.1 μg/mL was sufficient for detection of p53 in 10 μg of Rat brain lysate by colorimetricimmunoblot analysis using Goat anti-Mouse IgG: HRP as the secondary antibody.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer PBS pH 7.4 containing 50 % Glycerol and 0.09 % Sodium Azide as preservative.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Haltbarkeit 12 months