anti-Ratte (Rattus) p53 Antikörper für Immunofluorescence (Cultured Cells)

Recommended p53 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Protein P53 (TP53) Antikörper
  • tp53
  • p53
  • TP53
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • TpMs
  • BCC7
  • LFS1
  • P53
  • TRP53
  • Trp53
  • Xp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • cellular tumor antigen p53
  • tumor protein p53
  • tumor supressor p53
  • p53 tumor suppressor
  • transformation related protein 53
  • transformation related protein 53, pseudogene
  • trichoplein, keratin filament binding
  • Wistar clone pR53P1 p53 pseudogene
  • CpipJ_CPIJ002758
  • TP53
  • tp53
  • P53
  • Trp53
  • Trp53-ps
  • TCHP
  • Tp53
  • p53-ps
Epitop
AA 240-290, Wild Type
170
118
84
83
69
65
55
55
54
53
49
47
46
45
40
32
31
31
25
23
23
22
20
18
16
16
15
15
15
15
14
14
11
10
10
9
9
9
8
8
7
7
7
7
6
6
6
6
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
2329
513
418
186
127
94
85
82
34
23
20
18
17
16
15
14
6
4
4
4
4
3
3
3
2
2
1
1
Wirt
Kaninchen
1321
1113
7
3
3
1
1
1
Klonalität
Polyklonal
Konjugat
Dieser p53 Antikörper ist unkonjugiert
78
76
63
53
45
44
30
30
25
25
25
24
24
24
24
23
23
23
21
20
19
18
14
14
14
14
14
12
7
5
5
5
5
5
5
5
5
4
3
2
2
2
Applikation
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
1856
746
718
715
614
596
424
340
300
178
72
41
32
31
18
17
15
15
12
9
9
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Optionen
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Produktnummer ABIN723935
315,94 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN909774 IF (cc) IF (p) Alexa Fluor 350 Rabbit IgG AA 240-290, Wild Type Anmelden zum Anzeigen Polyclonal
1 ABIN909772 IF (cc) IF (p) Alexa Fluor 488 Rabbit IgG AA 240-290, Wild Type Anmelden zum Anzeigen Polyclonal
1 ABIN909773 IF (cc) IF (p) Alexa Fluor 555 Rabbit IgG AA 240-290, Wild Type Anmelden zum Anzeigen Polyclonal
1 ABIN2808148 IF (cc) IF (p) Alexa Fluor 594 Rabbit IgG AA 240-290 Anmelden zum Anzeigen Polyclonal
1 ABIN909770 IF (cc) IF (p) Alexa Fluor 647 Rabbit IgG AA 240-290, Wild Type Anmelden zum Anzeigen Polyclonal
1 ABIN723938 IF (cc) IF (p) Cy3 Rabbit IgG AA 240-290, Wild Type Anmelden zum Anzeigen Polyclonal
1 ABIN723939 IF (cc) IF (p) Cy5 Rabbit IgG AA 240-290, Wild Type Anmelden zum Anzeigen Polyclonal
1 ABIN723940 IF (cc) IF (p) Cy5.5 Rabbit IgG AA 240-290, Wild Type Anmelden zum Anzeigen Polyclonal
1 ABIN723941 IF (cc) IF (p) Cy7 Rabbit IgG AA 240-290, Wild Type Anmelden zum Anzeigen Polyclonal
1 ABIN723942 IF (cc) IF (p) FITC Rabbit IgG AA 240-290, Wild Type Anmelden zum Anzeigen Polyclonal
1 ABIN5008199 IF (cc) IF (p) Alexa Fluor 680 Rabbit IgG AA 240-290 Anmelden zum Anzeigen Polyclonal
1 ABIN5008200 IF (cc) IF (p) Alexa Fluor 750 Rabbit IgG AA 240-290 Anmelden zum Anzeigen Polyclonal

anti-p53 Antikörper für Immunofluorescence (Cultured Cells) mit den meisten Publikationen

Ähnliche anti-p53 Antikörper

Applikation / Reaktivität Ratte (Rattus)
Chromatin Immunoprecipitation (ChIP) 1 Antikörper
Cytometry by Time of Flight (CyTOF) 4 Antikörper
ELISA 128 Antikörper
Enzyme Immunoassay (EIA) 2 Antikörper
Flow Cytometry (FACS) 72 Antikörper
Gel Shift (GS) 3 Antikörper
Immunochromatography (IC) 7 Antikörper
Immunocytochemistry (ICC) 64 Antikörper
Immunofluorescence (IF) 116 Antikörper
Immunofluorescence (Cultured Cells) (IF (cc)) 13 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 13 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 73 Antikörper
Immunohistochemistry (IHC) 104 Antikörper
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antikörper
Immunohistochemistry (Frozen Sections) (IHC (fro)) 59 Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 78 Antikörper
Immunoprecipitation (IP) 68 Antikörper
Intracellular Staining (ICS) 1 Antikörper
Radioimmunoassay (RIA) 1 Antikörper
Western Blotting (WB) 298 Antikörper

General

Antigen Tumor Protein P53 (TP53) Antikörper
Epitop AA 240-290, Wild Type
(170), (118), (84), (83), (69), (65), (55), (55), (54), (53), (49), (47), (46), (45), (40), (32), (31), (31), (25), (23), (23), (22), (20), (18), (16), (16), (15), (15), (15), (15), (14), (14), (11), (10), (10), (9), (9), (9), (8), (8), (7), (7), (7), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(2329), (513), (418), (186), (127), (94), (85), (82), (34), (23), (20), (18), (17), (16), (15), (14), (6), (4), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1)
Wirt Kaninchen
(1321), (1113), (7), (3), (3), (1), (1), (1)
Klonalität
Polyklonal
Konjugat Dieser p53 Antikörper ist unkonjugiert
(78), (76), (63), (53), (45), (44), (30), (30), (25), (25), (25), (24), (24), (24), (24), (23), (23), (23), (21), (20), (19), (18), (14), (14), (14), (14), (14), (12), (7), (5), (5), (5), (5), (5), (5), (5), (5), (4), (3), (2), (2), (2)
Applikation Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(1856), (746), (718), (715), (614), (596), (424), (340), (300), (178), (72), (41), (32), (31), (18), (17), (15), (15), (12), (9), (9), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 4 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-p53 Antikörper

Target Details p53 Anwendungsinformationen Handhabung ProductDetails: References for anti-p53 antibody (ABIN723935) Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human P53
Isotyp IgG

Target Details p53

Produktdetails anti-p53 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-p53 antibody (ABIN723935) Bilder zurück nach oben
Antigen
Andere Bezeichnung P53 Protein (TP53 Antibody Abstract)
Hintergrund

Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis, the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.

Subcellular location: Cytoplasm, Nucleus

Synonyms: P53, BCC7, LFS1, TRP53, Cellular tumor antigen p53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53, TP53

Gen-ID 7157
UniProt P04637
Pathways p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie

Anwendungsinformationen

Produktdetails anti-p53 Antikörper Target Details p53 Handhabung ProductDetails: References for anti-p53 antibody (ABIN723935) Bilder zurück nach oben
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen ProductDetails: References for anti-p53 antibody (ABIN723935) Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

ProductDetails: References for anti-p53 antibody (ABIN723935)

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Wang, Liu, Liu, Chen, Liu, Kuang: "Hypoxia Inhibits Myogenic Differentiation through p53 Protein-dependent Induction of Bhlhe40 Protein." in: The Journal of biological chemistry, Vol. 290, Issue 50, pp. 29707-16, 2015

Hong, Shen, Liu, Li, Huang, Shi: "Developmental toxicity of three hexabromocyclododecane diastereoisomers in embryos of the marine medaka Oryzias melastigma." in: Marine pollution bulletin, Vol. 101, Issue 1, pp. 110-8, 2015

Chen, Shi, Liu, Fang, Zhang, Zhao: "Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis." in: BMC cancer, Vol. 12, pp. 464, 2012 (1:1000).

Carry, Banssillon: "[Intra-abdominal pressure]." in: Annales francaises d'anesthesie et de reanimation, Vol. 13, Issue 3, pp. 381-99, 1995 Von den Autoren verwendete Methode: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Rat (Rattus)).

Bilder

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen Handhabung ProductDetails: References for anti-p53 antibody (ABIN723935) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-p53 Antikörper (Tumor Protein P53) (AA 240-290) (ABIN723935) Formalin-fixed and paraffin embedded human ovarian carcinoma labeled with Rabbit Anti...
SDS-PAGE (SDS) image for anti-p53 Antikörper (Tumor Protein P53) (AA 240-290) (ABIN723935) 1 rat brain, L2 human colon carcinoma lysates probed (ABIN723935) at 1:200 in 4 °C. F...
Immunofluorescence (IF) image for anti-p53 Antikörper (Tumor Protein P53) (AA 240-290) (ABIN723935) Image kindly submitted by Piotr Mamczur from Wroclaw University. Immunofluorescent lo...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-p53 Antikörper (Tumor Protein P53) (AA 240-290) (ABIN723935) Formalin-fixed and paraffin embedded human ovarian carcinoma labeled with Rabbit Anti...