anti-Human p53 Antikörper für Immunohistochemistry

Recommended p53 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Protein P53 (TP53) Antikörper
  • tp53
  • p53
  • TP53
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • TpMs
  • BCC7
  • LFS1
  • P53
  • TRP53
  • Trp53
  • Xp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • cellular tumor antigen p53
  • tumor protein p53
  • tumor supressor p53
  • p53 tumor suppressor
  • transformation related protein 53
  • transformation related protein 53, pseudogene
  • trichoplein, keratin filament binding
  • Wistar clone pR53P1 p53 pseudogene
  • CpipJ_CPIJ002758
  • TP53
  • tp53
  • P53
  • Trp53
  • Trp53-ps
  • TCHP
  • Tp53
  • p53-ps
Epitop
N-Term
170
117
84
83
69
65
55
55
54
53
49
47
46
45
40
32
31
31
25
23
23
22
20
18
17
16
15
15
15
15
15
14
11
10
10
9
9
9
8
8
7
7
7
7
6
6
6
6
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Schwein, Kaninchen, Ratte (Rattus), Schaf
2329
514
418
186
126
94
85
81
34
22
19
18
16
16
15
13
6
4
4
4
4
3
3
2
2
2
1
1
Wirt
Kaninchen
1321
1113
7
3
3
1
1
1
Klonalität
Polyklonal
Konjugat
Dieser p53 Antikörper ist unkonjugiert
78
76
63
53
45
44
30
30
25
25
25
24
24
24
24
23
23
23
21
20
19
18
14
14
14
14
14
12
7
5
5
5
5
5
5
5
5
4
3
2
2
2
Applikation
Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (IHC), Western Blotting (WB)
1856
746
719
714
614
596
424
340
300
179
72
41
32
31
18
16
15
15
13
9
9
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Optionen
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Bilder

Produktnummer ABIN2779317
358,51 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
9.637035 ABIN2779318 ChIP IHC WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 1
9.637035 ABIN2792141 IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal 1
9.637035 ABIN1531939 IHC ELISA WB Rabbit IgG pSer6 Anmelden zum Anzeigen Polyclonal 1
9.637035 ABIN1532971 IHC ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal 1
9.637035 ABIN4342743 ICC IF IHC IHC (p) IP WB Rabbit pSer15 Anmelden zum Anzeigen Polyclonal 2
9.637035 ABIN2482441 FACS IP RIA IHC ELISA WB Atto 390 Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482442 FACS IP RIA IHC ELISA WB Atto 488 Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482443 FACS IP RIA IHC ELISA WB Atto 565 Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482444 FACS IP RIA IHC ELISA WB Atto 594 Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482445 FACS IP RIA IHC ELISA WB Atto 633 Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482446 FACS IP RIA IHC ELISA WB Atto 655 Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482447 FACS IP RIA IHC ELISA WB Atto 680 Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482448 FACS IP RIA IHC ELISA WB Atto 700 Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482449 FACS IP RIA IHC ELISA WB Alkaline Phosphatase (AP) Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482450 FACS IP RIA IHC ELISA WB APC Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482451 FACS IP RIA IHC ELISA WB Biotin Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482453 FACS IP RIA IHC ELISA WB HRP Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482454 FACS IP RIA IHC ELISA WB PE-Atto 594 Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482455 FACS IP RIA IHC ELISA WB PerCP Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1
9.637035 ABIN2482456 FACS IP RIA IHC ELISA WB PE Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801 1

anti-p53 Antikörper für Immunohistochemistry mit den meisten Publikationen

Ähnliche anti-p53 Antikörper

Applikation / Reaktivität Human Ratte (Rattus) Rind (Kuh) Schwein Kaninchen Hund Pferd Schaf
Immunofluorescence (fixed cells) (IF/ICC) 28 Antikörper 13 Antikörper 2 Antikörper 1 Antikörper 1 Antikörper
Cytometry by Time of Flight (CyTOF) 18 Antikörper 4 Antikörper 4 Antikörper 6 Antikörper
In Vivo Imaging (IVI) 1 Antikörper
Simple Western (SimWes) 9 Antikörper 3 Antikörper 3 Antikörper
Western Blotting (WB) 1773 Antikörper 100 Antikörper 9 Antikörper 8 Antikörper 298 Antikörper 54 Antikörper 19 Antikörper

General

Antigen Tumor Protein P53 (TP53) Antikörper
Epitop N-Term
(170), (117), (84), (83), (69), (65), (55), (55), (54), (53), (49), (47), (46), (45), (40), (32), (31), (31), (25), (23), (23), (22), (20), (18), (17), (16), (15), (15), (15), (15), (15), (14), (11), (10), (10), (9), (9), (9), (8), (8), (7), (7), (7), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Schwein, Kaninchen, Ratte (Rattus), Schaf
(2329), (514), (418), (186), (126), (94), (85), (81), (34), (22), (19), (18), (16), (16), (15), (13), (6), (4), (4), (4), (4), (3), (3), (2), (2), (2), (1), (1)
Wirt Kaninchen
(1321), (1113), (7), (3), (3), (1), (1), (1)
Klonalität
Polyklonal
Konjugat Dieser p53 Antikörper ist unkonjugiert
(78), (76), (63), (53), (45), (44), (30), (30), (25), (25), (25), (24), (24), (24), (24), (23), (23), (23), (21), (20), (19), (18), (14), (14), (14), (14), (14), (12), (7), (5), (5), (5), (5), (5), (5), (5), (5), (4), (3), (2), (2), (2)
Applikation Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (IHC), Western Blotting (WB)
(1856), (746), (719), (714), (614), (596), (424), (340), (300), (179), (72), (41), (32), (31), (18), (16), (15), (15), (13), (9), (9), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-p53 Antikörper

Target Details p53 Anwendungsinformationen Handhabung ProductDetails: References for anti-p53 antibody (ABIN2779317) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN985382.
Sequenz EEPQSDPSVE PPLSQETFSD LWKLLPENNV LSPLPSQAMD DLMLSPDDIE
Homologie Cow: 100%, Dog: 80%, Guinea Pig: 90%, Horse: 90%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 90%, Sheep: 100%
Produktmerkmale This is a rabbit polyclonal antibody against TP53. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human TP53

Target Details p53

Produktdetails anti-p53 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-p53 antibody (ABIN2779317) Bilder zurück nach oben
Antigen
Andere Bezeichnung TP53 (TP53 Antibody Abstract)
Hintergrund TP53 acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. This gene encodes tumor protein p53, which responds to diverse cellular stresses to regulate target genes that induce cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. p53 protein is expressed at low level in normal cells and at a high level in a variety of transformed cell lines, where it's believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing transcription activation, DNA-binding, and oligomerization domains. It is postulated to bind to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of this gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome. Multiple p53 variants due to alternative promoters and multiple alternative splicing have been found. These variants encode distinct isoforms, which can regulate p53 transcriptional activity.
Alias Symbols: LFS1, TRP53, p53
Protein Size: 393
Molekulargewicht 44 kDa
Gen-ID 7157
NCBI Accession NM_000546, NP_000537
UniProt P04637
Pathways p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie

Anwendungsinformationen

Produktdetails anti-p53 Antikörper Target Details p53 Handhabung ProductDetails: References for anti-p53 antibody (ABIN2779317) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 393 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen ProductDetails: References for anti-p53 antibody (ABIN2779317) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

ProductDetails: References for anti-p53 antibody (ABIN2779317)

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Boehme, Kulikov, Blattner: "p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 22, pp. 7785-90, 2008

Bilder

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen Handhabung ProductDetails: References for anti-p53 antibody (ABIN2779317) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-p53 Antikörper (Tumor Protein P53) (N-Term) (ABIN2779317) anti-Tumor Protein P53 (TP53) (N-Term) antibody
Western Blotting (WB) image for anti-p53 Antikörper (Tumor Protein P53) (N-Term) (ABIN2779317) Host: Rabbit
Target Name: TP53
Sample Tissue: Human Fetal Liver
...
Western Blotting (WB) image for anti-p53 Antikörper (Tumor Protein P53) (N-Term) (ABIN2779317) Host: Rabbit
Target Name: TP53
Sample Tissue: Human Adult Placenta