anti-Ratte (Rattus) NOXA Antikörper für ELISA

Recommended NOXA Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) Antikörper
  • TN3
  • PMAIP1
  • zgc:162379
  • APR
  • NOXA
  • Noxa
  • phorbol-12-myristate-13-acetate-induced protein 1
  • PMAIP1
  • pmaip1
  • Pmaip1
Reaktivität
Human, Maus, Ratte (Rattus)
95
79
45
1
Wirt
Maus
45
41
27
17
Klonalität
Monoklonal
Konjugat
Dieser NOXA Antikörper ist konjugiert mit Biotin
5
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
1
1
Applikation
ELISA
124
36
35
24
22
21
2
1
1
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Produktnummer ABIN4235450
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1031489 IHC ELISA WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal 2
1 ABIN4340479 ELISA ICC IF IHC IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN1888222 IHC ELISA WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal
1 ABIN1584920 IHC ELISA WB Rabbit Anmelden zum Anzeigen Polyclonal

General

Antigen Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(95), (79), (45), (1)
Wirt Maus
(45), (41), (27), (17)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser NOXA Antikörper ist konjugiert mit Biotin
(5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1)
Applikation ELISA
(124), (36), (35), (24), (22), (21), (2), (1), (1)
Pubmed 20 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-NOXA Antikörper

Target Details NOXA Anwendungsinformationen Handhabung Referenzen für anti-NOXA Antikörper (ABIN4235450) Bilder
Spezifität An ~80 kD background band may also be seen in Jurkat cell lysate.
Reinigung Protein G purified
Immunogen Noxa Antibody was developed by immunizing mice with a fusion protein containing human Noxa.
Klon 114C307-1
Isotyp IgG1 kappa

Target Details NOXA

Produktdetails anti-NOXA Antikörper Anwendungsinformationen Handhabung Referenzen für anti-NOXA Antikörper (ABIN4235450) Bilder zurück nach oben
Antigen
Andere Bezeichnung Noxa (PMAIP1 Antibody Abstract)
Hintergrund Gene Symbol: PMAIP1
Gen-ID 5366
Forschungsgebiet Apoptosis/Necrosis, Cancer
Pathways p53 Signalweg, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus

Anwendungsinformationen

Produktdetails anti-NOXA Antikörper Target Details NOXA Handhabung Referenzen für anti-NOXA Antikörper (ABIN4235450) Bilder zurück nach oben
Applikationshinweise ELISA 1:100-1:2000Immunocytochemistry and Immunofluorescence, See Yakovlev et all (2003) for details.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-NOXA Antikörper Target Details NOXA Anwendungsinformationen Referenzen für anti-NOXA Antikörper (ABIN4235450) Bilder zurück nach oben
Format Liquid
Buffer PBS
Buffer contains: 0.05 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C. Do not freeze.

Referenzen für anti-NOXA Antikörper (ABIN4235450)

Produktdetails anti-NOXA Antikörper Target Details NOXA Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Adamski, Price, Dive, Makin: "Hypoxia-induced cytotoxic drug resistance in osteosarcoma is independent of HIF-1Alpha." in: PLoS ONE, Vol. 8, Issue 6, pp. e65304, 2013

Tromp, Geest, Breij, Elias, van Laar, Luijks, Kater, Beaumont, van Oers, Eldering: "Tipping the Noxa/Mcl-1 balance overcomes ABT-737 resistance in chronic lymphocytic leukemia." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 2, pp. 487-98, 2012

Chen, Huang, Chu, Chen, Chou, Wang, Kulp, Teng, Wang, Chen: "Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression." in: The Journal of biological chemistry, Vol. 286, Issue 12, pp. 9968-76, 2011 Weitere Details: Western Blotting

Chu, Terrano, Chambers: "Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration." in: Biochemical pharmacology, Vol. 83, Issue 2, pp. 199-206, 2011

Amschler, Schön, Pletz, Wallbrecht, Erpenbeck, Schön: "NF-kappaB inhibition through proteasome inhibition or IKKbeta blockade increases the susceptibility of melanoma cells to cytostatic treatment through distinct pathways." in: The Journal of investigative dermatology, Vol. 130, Issue 4, pp. 1073-86, 2010

High, Szymanska, Wilczynska-Kalak, Barber, OBrien, Khaw, Vikstrom, Roberts, Lock: "The Bcl-2 homology domain 3 mimetic ABT-737 targets the apoptotic machinery in acute lymphoblastic leukemia resulting in synergistic in vitro and in vivo interactions with established drugs." in: Molecular pharmacology, Vol. 77, Issue 3, pp. 483-94, 2010

Tahir, Wass, Joseph, Devanarayan, Hessler, Zhang, Elmore, Kroeger, Tse, Rosenberg, Anderson: "Identification of expression signatures predictive of sensitivity to the Bcl-2 family member inhibitor ABT-263 in small cell lung carcinoma and leukemia/lymphoma cell lines." in: Molecular cancer therapeutics, Vol. 9, Issue 3, pp. 545-57, 2010 Weitere Details: Western Blotting

Vilgelm, Washington, Wei, Chen, Prassolov, Zaika: "Interactions of the p53 protein family in cellular stress response in gastrointestinal tumors." in: Molecular cancer therapeutics, Vol. 9, Issue 3, pp. 693-705, 2010

Lopez, Zhang, George, Liu, Pang, Evans, Targy, Luo: "Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage." in: The Journal of biological chemistry, Vol. 285, Issue 20, pp. 15016-26, 2010

Sosa Seda, Mott, Akazawa, Barreyro, Bronk, Kaufmann, Gores: "Noxa mediates hepatic stellate cell apoptosis by proteasome inhibition." in: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 40, Issue 7, pp. 701-10, 2010

Zall, Weber, Besch, Zantl, Häcker: "Chemotherapeutic drugs sensitize human renal cell carcinoma cells to ABT-737 by a mechanism involving the Noxa-dependent inactivation of Mcl-1 or A1." in: Molecular cancer, Vol. 9, pp. 164, 2010

Fahham, Sardari, Ostad, Vaziri, Ghahremani: "C-terminal domain of p16(INK4a) is adequate in inducing cell cycle arrest, growth inhibition and CDK4/6 interaction similar to the full length protein in HT-1080 fibrosarcoma cells." in: Journal of cellular biochemistry, Vol. 111, Issue 6, pp. 1598-606, 2010 (Probematerial (Species): Human).

Bodet, Ménoret, Descamps, Pellat-Deceunynck, Bataille, Le Gouill, Moreau, Amiot, Gomez-Bougie: "BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma." in: British journal of cancer, Vol. 103, Issue 12, pp. 1808-14, 2010 (Probematerial (Species): Human). Weitere Details: Western Blotting

Stankiewicz, Livingstone, Mohseni, Mosser: "Regulation of heat-induced apoptosis by Mcl-1 degradation and its inhibition by Hsp70." in: Cell death and differentiation, Vol. 16, Issue 4, pp. 638-47, 2009

van Gent, Kater, Otto, Jaspers, Borghans, Vrisekoop, Ackermans, Ruiter, Wittebol, Eldering, van Oers, Tesselaar, Kersten, Miedema: "In vivo dynamics of stable chronic lymphocytic leukemia inversely correlate with somatic hypermutation levels and suggest no major leukemic turnover in bone marrow." in: Cancer research, Vol. 68, Issue 24, pp. 10137-44, 2008 (Probematerial (Species): Human). Weitere Details: Western Blotting

Zhang, Hao, Hu, Ye, Xie, Thorne, Hersey, Zhang: "Inhibition of apoptosis facilitates necrosis induced by cisplatin in gastric cancer cells." in: Anti-cancer drugs, Vol. 19, Issue 2, pp. 159-66, 2008 (Probematerial (Species): Human). Weitere Details: Western Blotting

Jiang, Lucas, Avery-Kiejda, Wade, deBock, Thorne, Allen, Hersey, Zhang: "Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress." in: Cancer research, Vol. 68, Issue 16, pp. 6708-17, 2008 (Probematerial (Species): Human). Weitere Details: Western Blotting

Hallaert, Jaspers, van Noesel, van Oers, Kater, Eldering: "c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches." in: Blood, Vol. 112, Issue 13, pp. 5141-9, 2008 (Probematerial (Species): Human). Weitere Details: Western Blotting

Lee, Belkhiri, Lockhart, Merchant, Glaeser, Harris, Washington, Brunt, Zaika, Kim, El-Rifai: "Overexpression of OATP1B3 confers apoptotic resistance in colon cancer." in: Cancer research, Vol. 68, Issue 24, pp. 10315-23, 2008 (Probematerial (Species): Human). Weitere Details: Western Blotting

Tahir, Yang, Anderson, Morgan-Lappe, Sarthy, Chen, Warner, Ng, Fesik, Elmore, Rosenberg, Tse: "Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737." in: Cancer research, Vol. 67, Issue 3, pp. 1176-83, 2007 Weitere Details: Western Blotting