anti-Human NOXA Antikörper für Immunocytochemistry

Recommended NOXA Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) Antikörper
  • TN3
  • PMAIP1
  • zgc:162379
  • APR
  • NOXA
  • Noxa
  • phorbol-12-myristate-13-acetate-induced protein 1
  • PMAIP1
  • pmaip1
  • Pmaip1
Reaktivität
Human, Maus, Ratte (Rattus)
95
79
45
1
Wirt
Maus
45
41
27
17
Klonalität
Monoklonal
Konjugat
Dieser NOXA Antikörper ist unkonjugiert
6
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
1
1
Applikation
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
123
35
34
25
21
20
2
1
1
Hersteller
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Bilder

Produktnummer ABIN269360
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN4340477 ICC IF IHC IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal 1
1 ABIN4340478 ELISA ICC IF WB Goat Anmelden zum Anzeigen Polyclonal 1
1 ABIN4340500 ICC IF IHC IHC (p) WB Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340479 ELISA ICC IF IHC IHC (p) WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN199496 ICC ELISA WB Mouse IgG1 Anmelden zum Anzeigen 114C307-1
1 ABIN4340474 ICC IF IHC IHC (p) WB Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340496 ICC IF IHC IHC (p) WB Alexa Fluor 405 Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340499 ICC IF IHC IHC (p) WB Alexa Fluor 700 Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340486 ICC IF IHC IHC (p) WB DyLight 680 Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340485 ICC IF IHC IHC (p) WB DyLight 650 Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340487 ICC IF IHC IHC (p) WB DyLight 488 Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340489 ICC IF IHC IHC (p) WB DyLight 755 Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340494 ICC IF IHC IHC (p) WB DyLight 405 Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340490 ICC IF IHC IHC (p) WB PerCP Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340493 ICC IF IHC IHC (p) WB DyLight 350 Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340492 ICC IF IHC IHC (p) WB DyLight 550 Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340497 ICC IF IHC IHC (p) WB Alexa Fluor 488 Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340498 ICC IF IHC IHC (p) WB Alexa Fluor 647 Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4994060 ICC IF IHC IHC (p) FITC Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1
1 ABIN4340484 ICC IF IHC IHC (p) WB Allophycocyanin Mouse IgG1 kappa Anmelden zum Anzeigen 114C307-1

General

Antigen Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) Antikörper
Reaktivität Human, Maus, Ratte (Rattus)
(95), (79), (45), (1)
Wirt Maus
(45), (41), (27), (17)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser NOXA Antikörper ist unkonjugiert
(6), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1)
Applikation Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
(123), (35), (34), (25), (21), (20), (2), (1), (1)
Pubmed 20 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-NOXA Antikörper

Target Details NOXA Anwendungsinformationen Handhabung Referenzen für anti-NOXA Antikörper (ABIN269360) Bilder
Spezifität An ~80 kD background band may also be seen in Jurkat cell lysate.
Reinigung Protein G purified
Immunogen Noxa Antibody was developed by immunizing mice with a fusion protein containing human Noxa.
Klon 114C307-1
Isotyp IgG1 kappa

Target Details NOXA

Produktdetails anti-NOXA Antikörper Anwendungsinformationen Handhabung Referenzen für anti-NOXA Antikörper (ABIN269360) Bilder zurück nach oben
Antigen
Andere Bezeichnung Noxa (PMAIP1 Antibody Abstract)
Hintergrund Gene Symbol: PMAIP1
Gen-ID 5366
UniProt Q13794
Forschungsgebiet Apoptosis/Necrosis, Cancer
Pathways p53 Signalweg, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus

Anwendungsinformationen

Produktdetails anti-NOXA Antikörper Target Details NOXA Handhabung Referenzen für anti-NOXA Antikörper (ABIN269360) Bilder zurück nach oben
Applikationshinweise Western Blot 1-2 μg/mL, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:20-1:1000, Immunohistochemistry-Paraffin 5 μg/mLImmunocytochemistry and Immunofluorescence, See Yakovlev et all (2003) for details.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-NOXA Antikörper Target Details NOXA Anwendungsinformationen Referenzen für anti-NOXA Antikörper (ABIN269360) Bilder zurück nach oben
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.05 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze-thaw cycles
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Referenzen für anti-NOXA Antikörper (ABIN269360)

Produktdetails anti-NOXA Antikörper Target Details NOXA Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Antignani, Segal, Simon, Kreitman, Huang, FitzGerald: "Essential role for Bim in mediating the apoptotic and antitumor activities of immunotoxins." in: Oncogene, Vol. 36, Issue 35, pp. 4953-4962, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Zhang, Huang, ONeill, Pang, Luo: "Bax/Bak activation in the absence of Bid, Bim, Puma, and p53." in: Cell death & disease, Vol. 7, pp. e2266, 2016 (Probematerial (Species): Human). Weitere Details: Western Blotting

Wei, Noto, Zaika, Romero-Gallo, Piazuelo, Schneider, El-Rifai, Correa, Peek, Zaika: "Bacterial CagA protein induces degradation of p53 protein in a p14ARF-dependent manner." in: Gut, Vol. 64, Issue 7, pp. 1040-8, 2015

Sigurðsson, Olesen, Dybboe, Lauritzen, Pedersen: "Constitutively active ErbB2 regulates cisplatin-induced cell death in breast cancer cells via pro- and antiapoptotic mechanisms." in: Molecular cancer research : MCR, Vol. 13, Issue 1, pp. 63-77, 2015 (Probematerial (Species): Human). Weitere Details: Western Blotting

Wang, Lv, Cheng, Du, Chen, Li, Zhang: "Apoptosis induced by Ginkgo biloba (EGb761) in melanoma cells is Mcl-1-dependent." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124812, 2015 (Probematerial (Species): Human). Weitere Details: Western Blotting

Heinemann, Cullinane, De Paoli-Iseppi, Wilmott, Gunatilake, Madore, Strbenac, Yang, Gowrishankar, Tiffen, Prinjha, Smithers, McArthur, Hersey, Gallagher: "Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling." in: Oncotarget, Vol. 6, Issue 25, pp. 21507-21, 2015 (Probematerial (Species): Human). Weitere Details: Western Blotting

Godbersen, Humphries, Danilova, Kebbekus, Brown, Eastman, Danilov: "The Nedd8-activating enzyme inhibitor MLN4924 thwarts microenvironment-driven NF-κB activation and induces apoptosis in chronic lymphocytic leukemia B cells." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 6, pp. 1576-89, 2014 (Probematerial (Species): Human). Weitere Details: Western Blotting

Rao, Cha, Xu, Xu, Vandiver, Tyagi, Tokhunts, Koldobskiy, Fu, Barrow, Wu, Fiedler, Barrow, Snyder: "Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2." in: Molecular cell, Vol. 54, Issue 1, pp. 119-32, 2014 (Probematerial (Species): Human). Weitere Details: Western Blotting

Pang, Zhang, Lopez, Wang, Li, ONeill, Evans, George, Long, Chen, Luo: "The carboxyl-terminal tail of Noxa protein regulates the stability of Noxa and Mcl-1." in: The Journal of biological chemistry, Vol. 289, Issue 25, pp. 17802-11, 2014 (Probematerial (Species): Human). Weitere Details: Western Blotting

Thorburn, Andrysik, Staskiewicz, Gump, Maycotte, Oberst, Green, Espinosa, Thorburn: "Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels." in: Cell reports, Vol. 7, Issue 1, pp. 45-52, 2014 (Probematerial (Species): Human). Weitere Details: Western Blotting

Zinn, Gardner, Dobromilskaya, Murphy, Marchionni, Hann, Rudin: "Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer." in: Molecular cancer, Vol. 12, pp. 16, 2013

Dabir, Kluge, McColl, Liu, Lam, Halmos, Wildey, Dowlati: "PIAS3 activates the intrinsic apoptotic pathway in non-small cell lung cancer cells independent of p53 status." in: International journal of cancer, Vol. 134, Issue 5, pp. 1045-54, 2013 (Probematerial (Species): Human). Weitere Details: Western Blotting

Pascutti, Jak, Tromp, Derks, Remmerswaal, Thijssen, van Attekum, van Bochove, Luijks, Pals, van Lier, Kater, van Oers, Eldering: "IL-21 and CD40L signals from autologous T cells can induce antigen-independent proliferation of CLL cells." in: Blood, Vol. 122, Issue 17, pp. 3010-9, 2013 (Probematerial (Species): Human).

Parrondo, de Las Pozas, Reiner, Perez-Stable: "ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells." in: PeerJ, Vol. 1, pp. e144, 2013 (Probematerial (Species): Human). Weitere Details: Western Blotting

Wroblewski, Jiang, Croft, Farrelly, Zhang, Hersey: "OBATOCLAX and ABT-737 induce ER stress responses in human melanoma cells that limit induction of apoptosis." in: PLoS ONE, Vol. 8, Issue 12, pp. e84073, 2013 (Probematerial (Species): Human). Weitere Details: Western Blotting

Adamski, Price, Dive, Makin: "Hypoxia-induced cytotoxic drug resistance in osteosarcoma is independent of HIF-1Alpha." in: PLoS ONE, Vol. 8, Issue 6, pp. e65304, 2013

Thomas, Roberts, Kubli, Lee, Quinsay, Owens, Fischer, Sussman, Miyamoto, Gustafsson: "Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure." in: Genes & development, Vol. 27, Issue 12, pp. 1365-77, 2013 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Tromp, Geest, Breij, Elias, van Laar, Luijks, Kater, Beaumont, van Oers, Eldering: "Tipping the Noxa/Mcl-1 balance overcomes ABT-737 resistance in chronic lymphocytic leukemia." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 2, pp. 487-98, 2012 Weitere Details: Western Blotting

Wong, Anderson, Lee, Fairlie, Ludlam: "Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays." in: Cell death & disease, Vol. 3, pp. e288, 2012 (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Immunofluorescence

Ryder, McColl, Zhong, Distelhorst: "Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk." in: The Journal of biological chemistry, Vol. 287, Issue 33, pp. 27863-75, 2012 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Bilder

Produktdetails anti-NOXA Antikörper Target Details NOXA Anwendungsinformationen Handhabung Referenzen für anti-NOXA Antikörper (ABIN269360) zurück nach oben
Bilder des Herstellers
Immunofluorescence (IF) image for anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) antibody (ABIN269360) Immunocytochemistry/Immunofluorescence: Noxa Antibody (114C307.1) [ABIN269360] - Noxa...
Western Blotting (WB) image for anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) antibody (ABIN269360) Western Blot: Noxa Antibody (114C307.1) [ABIN269360] - Analysis using Azide Free vers...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) antibody (ABIN269360) Immunohistochemistry-Paraffin: Noxa Antibody (114C307.1) [ABIN269360] - Bouin-fixed, ...
Immunofluorescence (IF) image for anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) antibody (ABIN269360) Immunocytochemistry/Immunofluorescence: Noxa Antibody (114C307.1) [ABIN269360] - Anal...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) antibody (ABIN269360) Immunohistochemistry-Paraffin: Noxa Antibody (114C307.1) [ABIN269360] - Analysis usin...