anti-Human MDM2 Antikörper für Immunohistochemistry (Resin Sections)

Recommended MDM2 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) Antikörper
  • ACTFS
  • HDMX
  • hdm2
  • zgc:109834
  • 1700007J15Rik
  • AA415488
  • Mdm-2
  • MDM2 oncogene, E3 ubiquitin protein ligase
  • Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)
  • p53 E3 ubiquitin protein ligase
  • transformed 3T3 cell double minute 2 homolog (mouse)
  • transformed mouse 3T3 cell double minute 2
  • MDM2
  • mdm2
  • Mdm2
Epitop
AA 154-167
46
42
36
29
26
24
15
15
14
12
8
8
7
7
6
5
5
5
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Hund, Human, Affe, Ratte (Rattus)
379
136
94
13
7
6
4
2
2
2
2
2
2
1
1
1
Wirt
Maus
307
76
14
2
Klonalität
Monoklonal
Konjugat
Dieser MDM2 Antikörper ist unkonjugiert
12
12
12
9
9
9
3
3
3
3
3
3
3
3
3
3
3
2
2
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Resin Sections) (IHC (rs)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
264
137
108
84
71
40
38
24
13
12
12
11
4
3
2
1
1
1
1
1
1
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN214211
$ 451.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2475548 IHC (fro) IHC (rs) IHC (p) IP Mouse IgG1 AA 154-167 Anmelden zum Anzeigen SMP14 3
1 ABIN643835 IHC (fro) IHC (rs) IHC (p) Mouse IgG1 Anmelden zum Anzeigen
1 ABIN643838 IHC (fro) IHC (rs) IHC (p) IP Mouse IgG1 Anmelden zum Anzeigen

General

Antigen Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) Antikörper
Epitop AA 154-167
(46), (42), (36), (29), (26), (24), (15), (15), (14), (12), (8), (8), (7), (7), (6), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Hund, Human, Affe, Ratte (Rattus)
(379), (136), (94), (13), (7), (6), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Wirt Maus
(307), (76), (14), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser MDM2 Antikörper ist unkonjugiert
(12), (12), (12), (9), (9), (9), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2)
Applikation Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Resin Sections) (IHC (rs)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
(264), (137), (108), (84), (71), (40), (38), (24), (13), (12), (12), (11), (4), (3), (2), (1), (1), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-MDM2 Antikörper

Target Details MDM2 Anwendungsinformationen Handhabung Bilder
Marke IHC-plus™
Spezifität Recognizes the 90kD MDM2 protein, which forms a complex with p53 leading to p53 inhibition. MDM2 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. MDM2 is over expressed in a range of human malignancies, including soft tissue sarcomas, breast cancer and bladder cancer.
Homologie Percent identity by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Marmoset, Rat, Dog, Panda (100%) Bat, Cat, Bovine, Hamster, Elephant, Horse, Pig (93%) Mouse (86%).
Reinigung Purified IgG
Immunogen Synthetic peptide, CSRPSTSSRRRAISE, corresponding to amino acids 154-167 of human MDM2. Percent identity by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Marmoset, Rat, Dog, Panda (100%), Bat, Cat, Bovine, Hamster, Elephant, Horse, Pig (93%), Mouse (86%).

Type of Immunogen: Synthetic peptide
Klon SMP14
Isotyp IgG1

Target Details MDM2

Produktdetails anti-MDM2 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung MDM2 (MDM2 Antibody Abstract)
Hintergrund Name/Gene ID: MDM2

Synonyms: MDM2, ACTFS, Double minute 2 protein, Hdm2, MDM2 variant FB30, HDMX, Oncoprotein Mdm2, p53-binding protein Mdm2, MDM2 variant FB28
Gen-ID 4193
Forschungsgebiet Cancer, Cell Cycle, Transcription Factors
Pathways p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Autophagie

Anwendungsinformationen

Produktdetails anti-MDM2 Antikörper Target Details MDM2 Handhabung Bilder zurück nach oben
Applikationshinweise Approved: IHC-Fr, IHC-P (10 μg/mL), IHC-R, IP

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. Histology Positive Control Tissue: Breast Carcinoma.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-MDM2 Antikörper Target Details MDM2 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer PBS, 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing. Store undiluted.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung +4°C or -20°C, Avoid repeated freezing and thawing. Store undiluted.

Bilder

Produktdetails anti-MDM2 Antikörper Target Details MDM2 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 154-167) antibody (ABIN214211) Human Skin (formalin-fixed, paraffin-embedded) stained with MDM2 antibody ABIN214211 ...