E2F1 (E2F1) ELISA Kits

Bezeichnung:
E2F Transcription Factor 1 ELISA Kits (E2F1)
Auf www.antikoerper-online.de finden Sie aktuell 18 E2F Transcription Factor 1 (E2F1) ELISA Kits von 7 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen E2F1 Antikörper (385) und E2F1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 438 E2F1 Produkte verfügbar.
Synonyme:
ATE2FB, CG6376, dE2f, de2f1, def21, DmE2F-1, Dmel\\CG6376, Dp, drosE2F1, DRTF1/E2F, E(Sev-CycE)3A, E(var)3-93E, E(var)3-95E, E(var)93E, e2f, E2F-1, e2f1, E2FB, E2FB TRANSCRIPTION FACTOR, E2F TRANSCRIPTION FACTOR-1 E2F1, E2F transcription factor 1, Evar(3)164, l(3)07172, l(3)j3B1, l(3)j3C2, l(3)rM729, mKIAA4009, RBAP1, RBBP3, RBP3, xE2F

Weitere ELISA Kits für E2F1 Interaktionspartner

Fruit Fly (Drosophila melanogaster) E2F Transcription Factor 1 (E2F1) Interaktionspartner

  1. specific alternate transcripts of activator E2F (zeige E2F2 ELISA Kits), dE2F1, may have a dual function on cell cycle progression and cannot simply be viewed as a pro-proliferative transcription factor

  2. These findings identify a key function of E2F in skeletal muscle required for animal viability, and illustrate how the cell cycle regulator is repurposed in post-mitotic cells.

  3. Mechanistically, miR (zeige MYLIP ELISA Kits)-998 operates by repressing dCbl, a negative regulator of EGFR (zeige EGFR ELISA Kits) signaling. Significantly, dCbl is a critical target of miR (zeige MYLIP ELISA Kits)-998 since dCbl phenocopies the effects of miR (zeige MYLIP ELISA Kits)-998 on dE2f1-dependent apoptosis in rbf (zeige ATP5I ELISA Kits) mutants

  4. also demonstrated that an optimum level of dLin52 is needed for dE2F1/2 activity on the hid promoter

  5. Results show that regulation of e2f1 and PCNA by DREF in vivo is complex and the regulation mechanism may differ with the tissue and/or positions in the tissue.

  6. Loss of dE2F compromises mitochondrial function.

  7. Data propose that the interaction between ORC5 and dE2F1 may reflect a feedback mechanism between replication initiation proteins and dE2F1 that ensures that proliferating cells maintain a robust level of replication proteins for the next cell cycle.

  8. results suggest that E2F/DP complexes are essential for all genomic targeting of RBF1

  9. Inappropriate accumulation of E2f1 protein during S phase triggers the elimination of potentially hyperplastic cells via apoptosis in order to ensure normal development of rapidly proliferating tissues.

  10. endocycles of Drosophila are driven by a molecular oscillator in which the E2F1 transcription factor promotes CycE (zeige CCNE1 ELISA Kits) expression and S-phase initiation, S-phase then activates the CRL4(CDT2) ubiquitin ligase, and this in turn mediates the destruction of E2F1

Human E2F Transcription Factor 1 (E2F1) Interaktionspartner

  1. Specific E2Fs also have prognostic value in breast cancer, independent of clinical parameters. We discuss here recent advances in understanding of the RB-E2F pathway in breast cancer. We also discuss the application of genome-wide genetic screening efforts to gain insight into synthetic lethal interactions of CDK4/6 (zeige CDK4 ELISA Kits) inhibitors in breast cancer for the development of more effective combination therapies.

  2. Here, we introduce a transcriptional signature to specifically track CDK2 (zeige CDK2 ELISA Kits) activity. It responds to genetic and chemical perturbations in the CDK (zeige CDK4 ELISA Kits)-RB-E2F axis, correlates with mitotic rate in vitro and in vivo and reacts rapidly to changes in CDK2 (zeige CDK2 ELISA Kits) activity during cell cycle progression

  3. E2F transcription factor 1 (E2F1) downregulated micrRNA miR (zeige MLXIP ELISA Kits)-519d directly and miR (zeige MLXIP ELISA Kits)-519d downregulated Ras homolog gene family member C (RhoC (zeige RHOC ELISA Kits)) directly.

  4. REVIEW: the data available so far indicate that the proliferative and apoptotic functions of E2F1 in Hepatocellular carcinoma (HCC (zeige FAM126A ELISA Kits)) may coexist but the proliferative effect seems to be more pronounced than the apoptotic one

  5. our results established the significance of activating the KLF6-E2F1 axis in aggressive primary metastatic clear cell renal cell carcinoma

  6. High E2F1 expression is associated with glioma.

  7. H19 (zeige NCKAP1 ELISA Kits) is overexpressed and plays oncogenic role in PDAC through promoting cancer cell proliferation via the upregulation of E2F-1.

  8. E2F1 was significantly increased during Oral Tongue Carcinoma Metastasis.

  9. High E2F1 expression is associated with decreased radiosensitivity in nasopharyngeal carcinoma .

  10. nicotine-mediated induction of alpha7 nAChR (zeige CHRNA7 ELISA Kits) was reduced when E2F1 was depleted and in contrast elevated when STAT1 (zeige STAT1 ELISA Kits) was depleted by siRNAs.

Mouse (Murine) E2F Transcription Factor 1 (E2F1) Interaktionspartner

  1. The evidence has been presented that the retinoblastoma protein utilizes a cell-cycle-independent interaction with E2F1 to recruit EZH2 (zeige EZH2 ELISA Kits) to diverse repeat sequences.

  2. germ-line loss of E2f1 or E2f3b, but not E2f3a, protected mice against hepatocellular carcinoma

  3. E2F1 hinders skin wound healing by suppressing VEGF (zeige VEGFA ELISA Kits) expression, neovascularization, and macrophage recruitment. Strategies that target E2F1 may enhance wound healing.

  4. systems-level control of cell cycle arrest by pRB (zeige PGR ELISA Kits)-E2F and p27 (zeige CDKN1B ELISA Kits)-CDK (zeige CDK4 ELISA Kits) regulation, is reported.

  5. TERT (zeige TERT ELISA Kits) has a role in neointima formation through epigenetic regulation of proliferative E2F1 target gene expression in smooth muscle cells.

  6. inhibition of PDK4 (zeige PDK4 ELISA Kits) activity in Hepatocellular carcinoma cells increased cyclin E1 (zeige CCNE1 ELISA Kits), cyclin A2 (zeige CCNA2 ELISA Kits), and E2F1 proteins.

  7. Data indicate that adenosine and CGS21680 upregulate CD39 (zeige ENTPD1 ELISA Kits) and CD73 via E2F-1 and CREB (zeige CREB1 ELISA Kits).

  8. Expression of Kv10.1 (zeige KCNG3 ELISA Kits) driven by phosphorylated Rb/E2F1 contributes to G2/M progression of cancer and non-transformed cells.

  9. Spinal cord injury-induced activation of E2F1-2 mediates cell cycle activation, contributing to gliopathy and neuronal/tissue loss associated with motor impairments and post-traumatic hyperesthesia.

  10. In the initial stage of myocyte differentiation, transcription of the YB-1 (zeige YBX1 ELISA Kits) gene was regulated by E2F1 and Sp1 (zeige SP1 ELISA Kits), and was then gradually replaced under the control of both MyoD (zeige MYOD1 ELISA Kits) and myogenin (zeige MYOG ELISA Kits).

Xenopus laevis E2F Transcription Factor 1 (E2F1) Interaktionspartner

  1. Xphb1 represses E2F1 activity.

Arabidopsis thaliana E2F Transcription Factor 1 (E2F1) Interaktionspartner

  1. SIM (zeige SIM2 ELISA Kits) and SMR1 are involved in hyperphosphorylation of the cell-cycle regulator RBR1 and overexpression of E2F target genes.

  2. S6K1 interacts with retinoblastoma protein RBR via its N-terminal RBR binding motif, promotes its nuclear localization and consequent RBR-dependent repression of cell cycle genes through transcription factor E2FB.

  3. The Arabidopsis (Arabidopsis thaliana) DEL1 gene was identified as a transcriptional target of the classical E2Fb and E2Fc transcription factors.

  4. The authors found that S6K1 associates with the Retinoblastoma-related 1 (RBR1)-E2FB complex and this is partly mediated by its N-terminal LVxCxE motif.

  5. Results suggest that E2FB is one of the key targets for auxin to determine whether cells proliferate or whether they exit the cell cycle, enlarge, and endoreduplicate their DNA.

  6. AtE2Fa and AtE2Fb have specific expression patterns and may play similar but distinct roles during cell cycle progression.

E2F1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.

Alternative names and synonyms associated with E2F1

  • E2F transcription factor (E2f) Elisa Kit
  • E2F transcription factor 1 (E2F1) Elisa Kit
  • E2F transcription factor 1 (E2f1) Elisa Kit
  • E2F transcription factor 1 (e2f1) Elisa Kit
  • ATE2FB Elisa Kit
  • CG6376 Elisa Kit
  • dE2f Elisa Kit
  • de2f1 Elisa Kit
  • def21 Elisa Kit
  • DmE2F-1 Elisa Kit
  • Dmel\\CG6376 Elisa Kit
  • Dp Elisa Kit
  • drosE2F1 Elisa Kit
  • DRTF1/E2F Elisa Kit
  • E(Sev-CycE)3A Elisa Kit
  • E(var)3-93E Elisa Kit
  • E(var)3-95E Elisa Kit
  • E(var)93E Elisa Kit
  • e2f Elisa Kit
  • E2F-1 Elisa Kit
  • e2f1 Elisa Kit
  • E2FB Elisa Kit
  • E2FB TRANSCRIPTION FACTOR Elisa Kit
  • E2F TRANSCRIPTION FACTOR-1 E2F1 Elisa Kit
  • E2F transcription factor 1 Elisa Kit
  • Evar(3)164 Elisa Kit
  • l(3)07172 Elisa Kit
  • l(3)j3B1 Elisa Kit
  • l(3)j3C2 Elisa Kit
  • l(3)rM729 Elisa Kit
  • mKIAA4009 Elisa Kit
  • RBAP1 Elisa Kit
  • RBBP3 Elisa Kit
  • RBP3 Elisa Kit
  • xE2F Elisa Kit

Bezeichner auf Proteinebene für E2F1

CG6376-PA , CG6376-PB , CG6376-PC , CG6376-PD , E2-promoter binding factor , E2f-PA , E2f-PB , E2f-PC , E2f-PD , PBR3 , PRB-binding protein E2F-1 , RBAP-1 , RBBP-3 , retinoblastoma-associated protein 1 , retinoblastoma-binding protein 3 , transcription factor E2F1 , E2F-1 transcription factor , E2F-1

GENE ID SPEZIES
42550 Drosophila melanogaster
100069192 Equus caballus
1869 Homo sapiens
13555 Mus musculus
485839 Canis lupus familiaris
535369 Bos taurus
458184 Pan troglodytes
100036852 Xenopus laevis
396142 Gallus gallus
399489 Rattus norvegicus
100729531 Cavia porcellus
832283 Arabidopsis thaliana
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