anti-Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Antikörper

Bezeichnung:
anti-Nuclear Receptor Subfamily 5, Group A, Member 1 Antikörper (NR5A1)
Auf www.antikoerper-online.de finden Sie aktuell 81 Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Antikörper von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Nuclear Receptor Subfamily 5, Group A, Member 1 Kits (19) und Nuclear Receptor Subfamily 5, Group A, Member 1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 113 Nuclear Receptor Subfamily 5, Group A, Member 1 Produkte verfügbar.
Synonyme:
Ad4bp, Ad4BP/SF-1, ELP, ELP-3, ff1a, ftz, Ftz-F1, FTZ1, Ftzf1, NR5A1, POF7, Sf-1, SF-1/Ad4BP, SF1, SPGF8, SRXY3, zFF1, zFF1A, zFF1B

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Am meisten referenzierte anti-Nuclear Receptor Subfamily 5, Group A, Member 1 Antikörper

  1. Cow (Bovine) Polyclonal NR5A1 Primary Antibody für IHC, WB - ABIN2777447 : Li, Chang, Wang, Tsai, Jong, Chung: Steroidogenic factor 1 differentially regulates basal and inducible steroidogenic gene expression and steroid synthesis in human adrenocortical H295R cells. in The Journal of steroid biochemistry and molecular biology 2004 (PubMed)

  2. Human Polyclonal NR5A1 Primary Antibody für FACS, IHC (p) - ABIN651299 : Almeida, Soares, Ribeiro, Fragoso, Marins, Wakamatsu, Ressio, Nishi, Jorge, Lerario, Alves, Mendonca, Latronico: Steroidogenic factor 1 overexpression and gene amplification are more frequent in adrenocortical tumors from children than from adults. in The Journal of clinical endocrinology and metabolism 2010 (PubMed)

  3. Cow (Bovine) Polyclonal NR5A1 Primary Antibody für WB - ABIN2780108 : Fatchiyah, Zubair, Shima, Oka, Ishihara, Fukui-Katoh, Morohashi: Differential gene dosage effects of Ad4BP/SF-1 on target tissue development. in Biochemical and biophysical research communications 2006 (PubMed)

  4. Cow (Bovine) Polyclonal NR5A1 Primary Antibody für IHC, WB - ABIN2782282 : Derebecka-Holysz, Lehmann, Holysz, Trzeciak: SMAD3 inhibits SF-1-dependent activation of the CYP17 promoter in H295R cells. in Molecular and cellular biochemistry 2007 (PubMed)

Weitere Antikörper gegen Nuclear Receptor Subfamily 5, Group A, Member 1 Interaktionspartner

Zebrafish Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Interaktionspartner

  1. chemical inhibition of Nr5a2 function during hepatopancreas progenitor specification was sufficient to disrupt exocrine pancreas formation and enhance the size of the embryonic liver, suggesting that Nr5a2 regulates hepatic vs. pancreatic progenitor fate choice.

  2. ff1a functions in both slow and fast muscle morphogenesis in response to Hedgehog (zeige SHH Antikörper) signaling, and this function parallels the activity of another slow muscle gene, prox1 (zeige PROX1 Antikörper)

  3. The role of Sox9a in ff1a gene regulation and function was studied using sox9a morpholinos.

Human Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Interaktionspartner

  1. Ten novel heterozygous NR5A1 mutations were identified in 46,XY DSD (zeige FADS1 Antikörper) patients, including five nonsynonymous variants (p.Gly26Glu, p.Thr29Arg, p.Trp302Cys, p.Ala340Val, p.Leu358Pro), four stop-gain variants (p.Tyr211*, p.Cys247*, p.Tyr404*, p.Cys412*), and one frameshift variant (p.Glu395del)

  2. we show that a specific recurrent heterozygous missense mutation (p.Arg92Trp) in the accessory DNA-binding region of NR5A1 is associated with variable degree of testis development in 46,XX children and adults from four unrelated families

  3. we review genetic data generated through large-scale sequencing approaches that are changing our view of how this system works, including the recently described recurrent NR5A1 p.R92W mutation associated with testis development in 46,XX children

  4. The NR5A1 p.Arg92Gln variant, which has thus far only been seen in a family with 46,XY Disorder of Sex Development, most likely contributes to the ovotesticular Disorder of Sex Development in this case.

  5. Data suggest that the first screening step diagnosis for pituitary adenoma was determined based upon immunohistochemical (IHC) scores for Pit-1 (zeige POU1F1 Antikörper), SF-1, and ACTH (zeige POMC Antikörper).

  6. We analysed a Pakistani cohort of patients with 46,XY disorders of sex development (DSD (zeige FADS1 Antikörper)), presenting with variable degrees of gonadal dysgenesis, for NR5A1 mutations. The study identified three mutations (p.Tyr03X, p.Glu07X and p.Gln299HisfsX386), of which two are novel, in these patients with 46,XY DSD (zeige FADS1 Antikörper).

  7. demonstrate aberrant expressions of SF-1 and LRH-1 (zeige NR5A2 Antikörper) in endometriotic granulosa-lutein cells

  8. this is the first report of the NR5A1 splice site mutation, which was proven to be deleterious by the RT-PCR method.

  9. SF1 SNPs are associated with serum uric acid levels in Chinese males and females.

  10. Describe microcystic stromal tumor as a distinctive ovarian sex cord-stromal neoplasm characterized by FOXL2 (zeige FOXL2 Antikörper), SF-1, WT-1 (zeige WT1 Antikörper), Cyclin D1 (zeige CCND1 Antikörper), and beta-catenin (zeige CTNNB1 Antikörper) nuclear expression and CTNNB1 (zeige CTNNB1 Antikörper) mutations.

Mouse (Murine) Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Interaktionspartner

  1. Our data suggested that lipid accumulation in the Leydig cells of the 46,XY disorders of sex development phenotype with a steroidogenic factor 1 mutation is due, at least in part, to the suppression of steroidogenic acute regulatory protein (zeige STAR Antikörper) and CYP11A1 (zeige CYP11A1 Antikörper), and a resulting increase in unmetabolized cholesterol.

  2. SF-1 (zeige SF1 Antikörper) is needed for proper development of fetal and adult Leydig cells but with distinct primary functions

  3. NR5A1 prevents centriole splitting by inhibiting centrosomal DNA-PK activation and beta-catenin (zeige CTNNB1 Antikörper) accumulation

  4. The results suggest that gonadal steroids do not influence the production of neurosteroids in the fetal brain, nor does SF-1 (zeige SF1 Antikörper) play a major role in the regulation of steroidogenic enzyme expression in the brain.

  5. MiR (zeige MLXIP Antikörper)-383 promoted the expression of miR (zeige MLXIP Antikörper)-320 which regulated granulosa cell functions by targeting E2F1 (zeige E2F1 Antikörper) and SF-1 (zeige SF1 Antikörper) proteins.

  6. Data indicate that genetic ablation of the Vanin-1 (Vnn1 (zeige VNN1 Antikörper)) gene in SF-1 (NR5A1) transgenic mice significantly reduced the severity of neoplastic lesions in the adrenal cortex.

  7. FOXL2 (zeige FOXL2 Antikörper) negatively regulates Sf1 (zeige SF1 Antikörper) expression by antagonizing WT1 (zeige WT1 Antikörper)-KTS during early ovarian development in mice

  8. we provide the evidence that the acidic residue (E199) located downstream from the core consensus SUMO site of NR5A1 is, at least in part, required for SUMOylation of NR5A1 and for its mediated target gene and protein expression.

  9. Data suggest that the regulation of StAR by transcription factors including SF-1 (zeige SF1 Antikörper), GATA-4 (zeige GATA4 Antikörper) and C/EBP-beta (zeige CEBPB Antikörper) maybe critical mechanism involved in low-dose MBP (zeige MBP Antikörper)-stimulated steroidogenesis.

  10. Data indicate that reduced numbers of steroidogenic factor 1-positive (SF1 (zeige SF1 Antikörper)(+)) progenitor cells and increased fetal Leydig cells (FLCs), and increased hedgehog (zeige SHH Antikörper) (Hh) activation led to decreased adult Leydig cells (ALCs) populations.

Pig (Porcine) Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Interaktionspartner

  1. NR5A1 variations influence meat color in a hypothalamus-pituitary-adrenal axis independent manner

Cow (Bovine) Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Interaktionspartner

  1. These results indicate that PCBs impair the secretory function of ovarian steroidogenic cells by disrupting steroidogenesis and increasing OT secretion, and the receptor SF-1 appears to be essentially involved in these processes.

  2. The SF-1 and beta-catenin pathway convergence on StarD7 expression may have important implications in the phospholipid uptake and transport, contributing to the normal trophoblast development.

  3. The role of the NR5A1 activating functions AF-1 & AF (zeige Psmd4 Antikörper)-2 was studied in luteinizing bovine theca cells. The regulation of the 3 NR5A1-controlled genes CYPA11, STAR, & INSL3 (zeige INSL3 Antikörper) apparently is not dependent on NR5A1 activating functions AF-1 (zeige Psmd4 Antikörper) or AF-2.

  4. Involvement of Ad4BP/SF-1, DAX-1 (zeige NR0B1 Antikörper), and COUP-TFII (zeige NR2F2 Antikörper) transcription factor on steroid production and luteinization in ovarian theca cells.

  5. GATA4 (zeige GATA4 Antikörper) and GATA6 (zeige GATA6 Antikörper) mRNA and proteins could be detected in bovine corpus luteum (CL). GATA6 (zeige GATA6 Antikörper) showed a marked decrease at the regressed luteal stage, like NR5A1, NR5A2 (zeige NR5A2 Antikörper), and the other steroidogenic markers.

Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect.

Alternative names and synonyms associated with Nuclear Receptor Subfamily 5, Group A, Member 1 (NR5A1)

  • nuclear receptor subfamily 5, group A, member 2 (nr5a2) Antikörper
  • nuclear receptor subfamily 5, group A, member 1 (NR5A1) Antikörper
  • nuclear receptor subfamily 5, group A, member 1 (nr5a1) Antikörper
  • steroidogenic factor 1 (SF-1) Antikörper
  • nuclear receptor subfamily 5, group A, member 1 (Nr5a1) Antikörper
  • steroidogenic factor 1-like (LOC100738392) Antikörper
  • Ad4bp Antikörper
  • Ad4BP/SF-1 Antikörper
  • ELP Antikörper
  • ELP-3 Antikörper
  • ff1a Antikörper
  • ftz Antikörper
  • Ftz-F1 Antikörper
  • FTZ1 Antikörper
  • Ftzf1 Antikörper
  • NR5A1 Antikörper
  • POF7 Antikörper
  • Sf-1 Antikörper
  • SF-1/Ad4BP Antikörper
  • SF1 Antikörper
  • SPGF8 Antikörper
  • SRXY3 Antikörper
  • zFF1 Antikörper
  • zFF1A Antikörper
  • zFF1B Antikörper

Bezeichner auf Proteinebene für NR5A1

LRH1 , fushi tarazu , nuclear receptor subfamily 5 group A member 2 , steroidogenic factor 1 , nuclear receptor subfamily 5, group A, member 1 , steroidgenic factor 1 , steroidogenic factor-1 , STF-1 , adrenal 4 binding protein , adrenal 4-binding protein , fushi tarazu factor homolog 1 , nuclear receptor AdBP4 , steroid hormone receptor Ad4BP , steroidogenic factor 1 nuclear receptor , embryonal LTR-binding protein , embryonal long terminal repeat-binding protein , fushi tarazu 1 factor homolog , steroid hydroxylase positive regulator , nuclear receptor subfamily 5 group A member 1 , steroidogenic factor-1 SF-1

GENE ID SPEZIES
30749 Danio rerio
751778 Taeniopygia guttata
100271747 Xenopus (Silurana) tropicalis
100534561 Oreochromis niloticus
2516 Homo sapiens
26423 Mus musculus
83826 Rattus norvegicus
609642 Canis lupus familiaris
397368 Sus scrofa
281948 Bos taurus
395960 Gallus gallus
100049145 Xenopus laevis
100033902 Equus caballus
443464 Ovis aries
100738392 Sus scrofa
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