anti-NR2C1 (NR2C1) Antikörper

Bezeichnung:
anti-Nuclear Receptor Subfamily 2, Group C, Member 1 Antikörper (NR2C1)
Auf www.antikoerper-online.de finden Sie aktuell 98 Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) Antikörper von 14 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NR2C1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 114 NR2C1 Produkte verfügbar.
Synonyme:
80.3, 4831444H07Rik, DKFZp468M0512, dor2, Eenr, NR2C1, Psg4, si:dkey-183c16.2, Tr2, TR2-11, xDOR2, zgc:110672

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anti-Human NR2C1 Antikörper:

anti-Mouse (Murine) NR2C1 Antikörper:

anti-Rat (Rattus) NR2C1 Antikörper:

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Am meisten referenzierte anti-NR2C1 Antikörper

  1. Human Polyclonal NR2C1 Primary Antibody für EIA, WB - ABIN953748 : Lin, Wang, Lee: Transcriptional regulation of the human TR2 orphan receptor gene by nuclear factor 1-A. in Biochemical and biophysical research communications 2006 (PubMed)
    Zeige alle 3 Referenzen für 953748

  2. Cow (Bovine) Polyclonal NR2C1 Primary Antibody für IHC, WB - ABIN2780499 : Li, Franco, Wei: Identification of histone deacetylase-3 domains that interact with the orphan nuclear receptor TR2. in Biochemical and biophysical research communications 2003 (PubMed)

Weitere Antikörper gegen NR2C1 Interaktionspartner

Human Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) Interaktionspartner

  1. DRED is a 540 kDa complex containing the nuclear orphan receptors TR2 and TR4, which form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites. TR2 & 4 mRNAs are expressed at all stages of murine and human erythropoiesis.

  2. TR2 that may exert an important repressor in regulating ER activity in mammary glands.

  3. TR2 and TR4 (zeige NR2C2 Antikörper) can have distinct functions. Existence of differential and bi-directional regulation between PPAR alpha (zeige PPARA Antikörper) and TR2/TR4 (zeige NR2C2 Antikörper). Possible roles in PPAR alpha (zeige PPARA Antikörper) signaling pathway in human keratinocytes.

  4. TR2 may function as a negative modulator to suppress androgen receptor function in prostate cancer. Further studies on how to control TR2 function may result in the ability to modulate AR function in prostate cancer.

  5. The NF1-A (zeige NFIA Antikörper) transcription factor plays an important role in the transcriptional activation of the TR2 gene expression via a promoter activating cis (zeige CISH Antikörper)-element.

Mouse (Murine) Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1) Interaktionspartner

  1. Nr2c1 may be a candidate for mediating parallel adaptive changes in cranial neural sensory specializations such as the olfactory epithelium, retina and mystacial vibrissae and in non-neural craniofacial features including teeth

  2. TR2/TR4 expression in sickle cell disease mice confers enhanced fetal hemoglobin synthesis and alleviated disease phenotypes

  3. in adult erythroid cells, TR2/TR4 (zeige NR2C2 Antikörper) bind to the embryonic beta-type globin promoters but not to the adult beta-globin (zeige HBB Antikörper) promoter.

  4. TR2 may not play essential roles in spermatogenesis and normal testis development, function, and maintenance. Alternatively, the roles of TR2 may be redundant and could be played by other close members of the nuclear receptor superfamily (TR2 receptor)

  5. DRED is a 540 kDa complex containing the nuclear orphan receptors TR2 and TR4, which form a heterodimer that binds to the epsilon and gamma globin promoter DR1 sites. TR2 & 4 mRNAs are expressed at all stages of murine and human erythropoiesis.

  6. These results suggest a SUMOylation-dependent partitioning and differential coregulator recruitment contribute to the maintenance of a homeostatic supply of activating, Tr2, thus fine-tuning Oct4 (zeige POU5F1 Antikörper) expression and regulating stem-cell proliferation.

  7. Silencing of the embryonic and fetal beta globin (zeige HBB Antikörper) genes is delayed in erythroid cells of Tr2 and Tr4 (zeige NR2C2 Antikörper) null mutant mice, whereas in transgenic mice expressing dominant-negative TR4 (zeige NR2C2 Antikörper) (dnTR4), human embryonic epsilon-globin (zeige HBe1 Antikörper) is activated in erythroid cells.

  8. TR2 and TR4 (zeige NR2C2 Antikörper) orphan nuclear receptors repress Gata1 (zeige GATA1 Antikörper) transcription.

  9. Retinoic acid-stimulated sequential phosphorylation, PML (zeige PML Antikörper) recruitment, and SUMOylation of nuclear receptor TR2 to suppress Oct4 (zeige POU5F1 Antikörper) expression

  10. Possible roles for TR2 and TR4 (zeige NR2C2 Antikörper) in early embryonic development by regulating key genes involved in stem cell self-renewal, commitment, and differentiation.

NR2C1 Antigen-Profil

Beschreibung des Gens

This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined.

Alternative names and synonyms associated with NR2C1

  • nuclear receptor subfamily 2, group C, member 1 (NR2C1) Antikörper
  • nuclear receptor subfamily 2, group C, member 1 (nr2c1) Antikörper
  • nuclear receptor subfamily 2, group C, member 1 (nr2c1-a) Antikörper
  • nuclear receptor subfamily 2, group C, member 1 (Nr2c1) Antikörper
  • 80.3 Antikörper
  • 4831444H07Rik Antikörper
  • DKFZp468M0512 Antikörper
  • dor2 Antikörper
  • Eenr Antikörper
  • NR2C1 Antikörper
  • Psg4 Antikörper
  • si:dkey-183c16.2 Antikörper
  • Tr2 Antikörper
  • TR2-11 Antikörper
  • xDOR2 Antikörper
  • zgc:110672 Antikörper

Bezeichner auf Proteinebene für NR2C1

nuclear receptor subfamily 2, group C, member 1 , Nuclear receptor subfamily 2 group C member 1 , TR2 nuclear hormone receptor , nuclear receptor subfamily 2 group C member 1 , nuclear receptor subfamily 2, group C isoform , orphan nuclear receptor TR2 , DOR2-A , developmental orphan receptor 2 , developmental orphan receptor 2-A , nuclear receptor subfamily 2 group C member 1-A , orphan nuclear receptor TR2-A , testicular receptor 2-A , xDOR2-A , 80-3 cNDA , early embryonic nuclear receptor , mTR2 , nuclear receptor subfamily 2, group H, member 1 , orphan receptor, TR2-11 , testicular receptor 2 , pregnancy specific beta-1-glycoprotein 4

GENE ID SPEZIES
467096 Pan troglodytes
100052073 Equus caballus
100174333 Pongo abelii
7181 Homo sapiens
553649 Danio rerio
399361 Xenopus laevis
373913 Gallus gallus
611980 Canis lupus familiaris
511407 Bos taurus
22025 Mus musculus
252924 Rattus norvegicus
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