RBPJ (RBPJ) ELISA Kits

Bezeichnung:
Recombination Signal Binding Protein For Immunoglobulin kappa J Region ELISA Kits (RBPJ)
Auf www.antikoerper-online.de finden Sie aktuell 0 Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) ELISA Kits von unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RBPJ Antikörper (86) und RBPJ Proteine (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 100 RBPJ Produkte verfügbar.
Synonyme:
AI843960, AOS3, CBF1, csl, Igkjrb, IGKJRB1, Igkrsbp, KBF2, RBP-J, RBP-J kappa, RBPjk, Rbpsuh, Su(H), SUH, XSu(H), xsu(h)1
list all ELISA KIts Gen GeneID UniProt
Ratte RBPJ RBPJ 679028  
Human RBPJ RBPJ 3516 Q06330
Maus RBPJ RBPJ 19664 P31266

Weitere Synonyme anzeigen

Weitere ELISA Kits für RBPJ Interaktionspartner

Human Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) Interaktionspartner

  1. RBPJ links MYC (zeige MYC ELISA Kits) and transcriptional control through CDK9 (zeige CDK9 ELISA Kits) in brain tumors, providing potential nodes of fragility for therapeutic intervention, potentially distinct from NOTCH (zeige NOTCH1 ELISA Kits)

  2. Mean CBF1 expression is significantly increased in isocitrate dehydrogenase 1 (IDH1 (zeige IDH1 ELISA Kits)) R132H mutant glioblastoma. Hypoxic regions of glioblastoma have higher CBF1 activation and exposure to low oxygen can induce its expression in glioma cells in vitro.

  3. structural and biophysical studies demonstrate that RITA (zeige ZNF331 ELISA Kits) binds RBP-J similarly to the RAM (zeige RAB27A ELISA Kits) (RBP-J-associated molecule) domain of Notch (zeige NOTCH1 ELISA Kits), our biochemical and cellular assays suggest that RITA (zeige ZNF331 ELISA Kits) interacts with additional regions in RBP-J.

  4. The present findings indicate that p53 (zeige TP53 ELISA Kits), in turn, decreases CSL expression, which can serve to enhance p53 (zeige TP53 ELISA Kits) activity in acute DNA damage response of cells.

  5. RBP-J mediated by miR (zeige MLXIP ELISA Kits)-133a probably contributed to the regulation of DCs maturation and activation in osteosarcoma

  6. These results suggest that PSK (zeige TAOK2 ELISA Kits) suppresses Hedgehog (zeige SHH ELISA Kits) signaling through down-regulation of MAML3 and RBPJ transcription under hypoxia, inhibiting the induction of a malignant phenotype in pancreatic cancer. Our results may lead to development of new treatments for refractory pancreatic cancer using PSK (zeige TAOK2 ELISA Kits) as a Hedgehog (zeige SHH ELISA Kits) inhibitor

  7. our findings reconcile the 2 biological events and point to a multistep process of CAF (zeige KAT2B ELISA Kits) activation under convergent CSL and p53 (zeige TP53 ELISA Kits) control. Activation of p53 (zeige TP53 ELISA Kits) provides a failsafe mechanism against consequences of compromised CSL activity in stromal cells.

  8. RBPJ polymorphism [rs874040(CC) allele] skews memory T cells toward a pro-inflammatory phenotype involving Notch (zeige NOTCH1 ELISA Kits) signaling, thus increasing the susceptibility to develop rheumatoid arthritis.

  9. The role of CSL-dependent and independent Notch (zeige NOTCH1 ELISA Kits) signaling pathways in cell apoptosis is described in normal tissue homeostasis and in tumorigenesis. (Review)

  10. These results support a model in which EBNA2 and EBNA3s compete for distinct subsets of RBPJ sites to regulate cell genes and where EBNA3 subset specificity is determined by interactions with other cell transcription factors.

Xenopus laevis Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) Interaktionspartner

  1. findings reveal that, in response to Wnt (zeige WNT2 ELISA Kits) signalling, Dishevelled (zeige DVL2 ELISA Kits) inhibits CSL (zeige SMPX ELISA Kits) transcription factors to regulate Notch (zeige NOTCH1 ELISA Kits) signalling and cell-fate decisions in vivo

  2. The study reports the identification and functional characterization of rbpj interacting and tubulin associated (RITA) (C12ORF52 (zeige C12orf52 ELISA Kits)) as a novel rbpj/CBF-1-interacting protein.

  3. The results suggest that a cell-to-cell interaction via the Notch (zeige NOTCH1 ELISA Kits)/Su(H) pathway has a significant role in the PGC (zeige PGC ELISA Kits) migration by regulating cell motility.

  4. This "target protector and rescue assay" demonstrates that the phenotypic defects associated with CUGBP1 inactivation in Xenopus are essentially due to the deregulation of Su(H) mRNA.

Mouse (Murine) Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) Interaktionspartner

  1. RBP-J-mediated Notch (zeige NOTCH1 ELISA Kits) signalling is critical for basophil-dependent immunoregulation. Deficiency of RBP-J influences the immunoregulatory functions of BA, which include activation of T cells and their differentiation into T helper cell subtypes.

  2. Data, including data from studies using cells from transgenic/knockout mice, suggest that Med1 (zeige MBD4 ELISA Kits) plays role in enamel formation; Med1 (zeige MBD4 ELISA Kits) induces Alpl (zeige ALPL ELISA Kits) via stimulation of Notch1 (zeige NOTCH1 ELISA Kits) signaling by forming Notch1 (zeige NOTCH1 ELISA Kits)-RBP-Jk complex on Alpl (zeige ALPL ELISA Kits) promoter. (Med1 (zeige MBD4 ELISA Kits) = mediator complex subunit 1 (zeige MED1 ELISA Kits); Alpl (zeige ALPL ELISA Kits) = alkaline phosphatase, liver-bone-kidney; Notch1 (zeige NOTCH1 ELISA Kits) = Notch gene homolog 1 (zeige NOTCH1 ELISA Kits); RBP-Jk = kappa J region recombining binding protein suppressor of hairless)

  3. study uncovered a regulatory network, where miR (zeige MLXIP ELISA Kits)-182 functions as an important new node that receives inputs from RBP-J and TNF-alpha (zeige TNF ELISA Kits) signaling and positively regulates inflammatory osteoclastogenesis; suppression of miR (zeige MLXIP ELISA Kits)-182 by RBP-J serves as an important mechanism that restrains TNF-alpha (zeige TNF ELISA Kits) induced osteoclastogenesis

  4. structural and biophysical studies demonstrate that RITA (zeige C12orf52 ELISA Kits) binds RBP-J similarly to the RAM (RBP-J-associated molecule) domain of Notch (zeige NOTCH1 ELISA Kits), our biochemical and cellular assays suggest that RITA (zeige C12orf52 ELISA Kits) interacts with additional regions in RBP-J.

  5. Intronic Flk1 (zeige KDR ELISA Kits) genetic enhancer element directs arterial-specific expression via RBPJ-mediated venous repression.

  6. RBP-J mediated by miR (zeige MLXIP ELISA Kits)-133a probably contributed to the regulation of DCs maturation and activation in osteosarcoma

  7. Rbpj-kappa mediated Notch (zeige NOTCH1 ELISA Kits) signaling plays a critical role in development of hypothalamic Kisspeptin neurons.

  8. Results reveal an essential role for canonical Notch (zeige NOTCH1 ELISA Kits)/RBP-J signaling in hippocampal synaptic plasticity and suggest that role, at least in part, is mediated by the regulation of GABAergic signaling

  9. The bone marrow contains a progenitor that expresses renin (zeige REN ELISA Kits) throughout development and possesses a B-lymphocyte (zeige AKAP17A ELISA Kits) pedigree. This cell requires RBP-J to differentiate.

  10. functions as a transcriptional repressor on the promoter of the microRNA miR (zeige MLXIP ELISA Kits)-155

RBPJ Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.

Alternative names and synonyms associated with RBPJ

  • recombination signal binding protein for immunoglobulin kappa J region (Rbpj) Elisa Kit
  • recombination signal binding protein for immunoglobulin kappa J region (RBPJ) Elisa Kit
  • recombination signal binding protein for immunoglobulin kappa J region (rbpj) Elisa Kit
  • AI843960 Elisa Kit
  • AOS3 Elisa Kit
  • CBF1 Elisa Kit
  • csl Elisa Kit
  • Igkjrb Elisa Kit
  • IGKJRB1 Elisa Kit
  • Igkrsbp Elisa Kit
  • KBF2 Elisa Kit
  • RBP-J Elisa Kit
  • RBP-J kappa Elisa Kit
  • RBPjk Elisa Kit
  • Rbpsuh Elisa Kit
  • Su(H) Elisa Kit
  • SUH Elisa Kit
  • XSu(H) Elisa Kit
  • xsu(h)1 Elisa Kit

Bezeichner auf Proteinebene für RBPJ

recombining binding protein suppressor of hairless , CBF-1 , H-2K binding factor-2 , RBP-J kappa , RBP-JK , immunoglobulin kappa J region recombination signal binding protein 1 , renal carcinoma antigen NY-REN-30 , suppressor of hairless homolog , X-Su(H) , suppressor of hairless protein 1 , suppressor of hairless protein homolog , J kappa-recombination signal-binding protein

GENE ID SPEZIES
679028 Rattus norvegicus
3516 Homo sapiens
399453 Xenopus laevis
19664 Mus musculus
767928 Bos taurus
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