anti-NOTCH2 (NOTCH2) Antikörper

Bezeichnung:
anti-Notch 2 Antikörper (NOTCH2)
Auf www.antikoerper-online.de finden Sie aktuell 201 Notch 2 (NOTCH2) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NOTCH2 Kits (17) und NOTCH2 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 239 NOTCH2 Produkte verfügbar.
Synonyme:
AGS2, AI853703, HJCYS, hN2, N2, notch6, sb:cb884

Meistgesuchte Reaktivitäten zu anti-NOTCH2 (NOTCH2) Antikörper

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anti-Human NOTCH2 Antikörper:

anti-Mouse (Murine) NOTCH2 Antikörper:

anti-Rat (Rattus) NOTCH2 Antikörper:

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Am meisten referenzierte anti-NOTCH2 Antikörper

  1. Mouse (Murine) Monoclonal NOTCH2 Primary Antibody für FACS - ABIN2663857 : Kraman, McCright: Functional conservation of Notch1 and Notch2 intracellular domains. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005 (PubMed)
    Zeige alle 6 Referenzen für 2663857

  2. Human Polyclonal NOTCH2 Primary Antibody für ELISA - ABIN1043688 : Bertrand, Eckfeldt, Lysholm, LeBien: Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells. in Leukemia 2001 (PubMed)
    Zeige alle 2 Referenzen für 1043688

  3. Human Polyclonal NOTCH2 Primary Antibody für EIA, IF - ABIN303122 : Siar, Ha, Aung, Nakano, Tsujigiwa, Nagatsuka, Ng, Kawakami: Immunolocalization of notch signaling protein molecules in a maxillary chondrosarcoma and its recurrent tumor. in European journal of medical research 2010 (PubMed)
    Zeige alle 2 Referenzen für 303122

  4. Human Polyclonal NOTCH2 Primary Antibody für ELISA, WB - ABIN185523 : Schwarzmeier, Hubmann, Düchler, Jäger, Shehata: Regulation of CD23 expression by Notch2 in B-cell chronic lymphocytic leukemia. in Leukemia & lymphoma 2004 (PubMed)

  5. Human Polyclonal NOTCH2 Primary Antibody für ELISA, WB - ABIN1536150 : Blaumueller, Qi, Zagouras, Artavanis-Tsakonas: Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. in Cell 1997 (PubMed)

  6. Cow (Bovine) Polyclonal NOTCH2 Primary Antibody für WB - ABIN2777549 : Tilley, Harvey, Heguy, Hackett, Wang, OConnor, Crystal: Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease. in American journal of respiratory and critical care medicine 2009 (PubMed)

Weitere Antikörper gegen NOTCH2 Interaktionspartner

Human Notch 2 (NOTCH2) Interaktionspartner

  1. In conclusion, Notch (zeige NOTCH1 Antikörper) siganling appears to be an important mediator of the liver inflammation by modulating hepatic IL-22 (zeige IL22 Antikörper)-secreting NKp46 (zeige NCR1 Antikörper)(+) innate lymphoid cells.

  2. The data showed that the overexpression of miR (zeige MLXIP Antikörper)-18a-5p could downregulate Notch2 expression and subsequently suppress endothelial-mesenchymal transition and cardiac fibrosis.

  3. Major genomic mutation profiles in lacrimal gland adenoid cystic carcinoma (LGACC) were uncovered by exome-seq. Although preliminary in nature, the Notch (zeige NOTCH1 Antikörper) pathway could be a potential therapeutic target for LGACC.

  4. Data indicate that mRNA high expression level of Notch1 (zeige NOTCH1 Antikörper) was associated with better overall survival (OS) for all NSCLC, hazard ratio (HR), better OS in adenocarcinoma (Ade), HR, as well as in squamous cell carcinoma (SCC (zeige CYP11A1 Antikörper)), HR, and mRNA high expression levels of Notch2 and Notch3 (zeige NOTCH3 Antikörper) were associated with worsen OS for all NSCLC, and mRNA high expression level of Notch4 (zeige NOTCH4 Antikörper) was not found to be associated with to OS for all NSCLC.

  5. Mutation in NOTCH2 gene is associated with nodal marginal zone lymphoma.

  6. Transgenic mice harboring Notch2 mutation analogous to that in patients with Hajdu-Cheney syndrome (HCS (zeige HLCS Antikörper)) are severely osteopenic because of enhanced bone resorption; this model has now been validated. Data from further studies in transgenic mice suggest that the HCS (zeige HLCS Antikörper) mutation in osteoblasts, but not in osteoclasts, causes osteopenia in this model.

  7. Intermittent compressive stress regulates Notch (zeige NOTCH1 Antikörper) receptor and target gene expression via the TGF-beta (zeige TGFB1 Antikörper) signaling pathway. Notch (zeige NOTCH1 Antikörper) signaling participates in TGF-beta (zeige TGFB1 Antikörper)-induced sclerostin (zeige SOST Antikörper) expression in periodontal ligament cells.

  8. The authors present novel structures of human ligands Jagged2 (zeige JAG2 Antikörper) and Delta-like4 and human Notch2, together with functional assays, which suggest that ligand-mediated coupling of membrane recognition and Notch (zeige NOTCH1 Antikörper) binding is likely to be critical in establishing the optimal context for Notch (zeige NOTCH1 Antikörper) signalling.

  9. Notch1 (zeige NOTCH1 Antikörper) and Notch2 are the primary Notch (zeige NOTCH1 Antikörper) receptors regulating epithelial cell homoeostasis in mouse and human stomach.

  10. our results indicated epidermal growth factor (zeige EGF PLURAL_@26348@)-like domain multiple 7 protein participates in growth hormone (zeige GH1 PLURAL_@26348@)-secreting pituitary adenoma proliferation and invasion regulation via Notch2/DLL3 (zeige DLL3 PLURAL_@26348@) signaling pathway. These findings raised the possibility that epidermal growth factor (zeige EGF PLURAL_@26348@)-like domain multiple 7 protein might serve as a useful biomarker to assess growth hormone (zeige GH1 PLURAL_@26348@)-secreting pituitary adenoma invasion and prognosis

Mouse (Murine) Notch 2 (NOTCH2) Interaktionspartner

  1. this study shows that Notch (zeige NOTCH1 Antikörper) signaling regulates basophils biological function, at least partially via the modulation of MAPK (zeige MAPK1 Antikörper)

  2. Postnatal development analysis revealed that in cilia-deficient corneal epithelial cells downregulation of the Notch (zeige NOTCH1 Antikörper) pathway precedes cell proliferation defects.

  3. The data showed that the overexpression of miR (zeige MLXIP Antikörper)-18a-5p could downregulate Notch2 expression and subsequently suppress endothelial-mesenchymal transition and cardiac fibrosis.

  4. these results show that ADAM10 (zeige ADAM10 Antikörper)-Notch (zeige NOTCH1 Antikörper) signaling in ovarian somatic cells governs the primordial follicle formation by controlling the development of ovarian pregranulosa cells.

  5. Transgenic mice harboring Notch2 mutation analogous to that in patients with Hajdu-Cheney syndrome (HCS (zeige HLCS Antikörper)) are severely osteopenic because of enhanced bone resorption; this model has now been validated. Data from further studies in transgenic mice suggest that the HCS (zeige HLCS Antikörper) mutation in osteoblasts, but not in osteoclasts, causes osteopenia in this model.

  6. Notch1 (zeige NOTCH1 Antikörper) and Notch2 are the primary Notch (zeige NOTCH1 Antikörper) receptors regulating epithelial cell homoeostasis in mouse and human stomach.

  7. These results suggested that Notch2 signaling is linked to c-Myc (zeige MYC Antikörper) expression and plays a key role in the regulation of MSC (zeige MSC Antikörper) proliferation.

  8. this study shows that Notch2 activity is required for the maintenance of lung tissue-resident memory CD103 (zeige ITGAE Antikörper)+ T cells

  9. In this study, authors use a smooth muscle-specific (zeige EIF3K Antikörper) deletion of Notch2 together with a global Notch3 (zeige NOTCH3 Antikörper) deletion to produce mice with combinations of mutant and wild-type Notch2/3 alleles in vascular smooth muscle cells

  10. 6955C-->T mutation in the Notch2 locus leading to cancellous and cortical bone osteopenia.

Cow (Bovine) Notch 2 (NOTCH2) Interaktionspartner

  1. bovine herpesvirus 1 ORF2 protein reduced the trans-activation potential of Notch1 (zeige NOTCH1 Antikörper) and Notch3 (zeige NOTCH3 Antikörper), suggesting that ORF2 interfered with the trans-activation potential of Notch (zeige NOTCH1 Antikörper).

Zebrafish Notch 2 (NOTCH2) Interaktionspartner

  1. DeltaC/Notch1a (zeige NOTCH1A Antikörper) and Notch2 signaling is responsible for a survival signal provided by xanthophores to melanophores.

NOTCH2 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NOTCH2

  • notch 2 (NOTCH2) Antikörper
  • notch 2 (notch2) Antikörper
  • notch 2 (Notch2) Antikörper
  • notch homolog 2 (notch2) Antikörper
  • AGS2 Antikörper
  • AI853703 Antikörper
  • HJCYS Antikörper
  • hN2 Antikörper
  • N2 Antikörper
  • notch6 Antikörper
  • sb:cb884 Antikörper

Bezeichner auf Proteinebene für anti-Notch 2 (NOTCH2) Antikörper

notch 2 , neurogenic locus notch homolog protein 2-like , Notch homolog 2 , neurogenic locus notch homolog protein 2 , Motch B , Notch gene homolog 2 , notch gene homolog 2 , notch receptor protein 6

GENE ID SPEZIES
581186 Strongylocentrotus purpuratus
100081510 Ornithorhynchus anatinus
100464781 Ailuropoda melanoleuca
100567900 Anolis carolinensis
100584613 Nomascus leucogenys
100224680 Taeniopygia guttata
4853 Homo sapiens
457173 Pan troglodytes
483148 Canis lupus familiaris
18129 Mus musculus
29492 Rattus norvegicus
100153369 Sus scrofa
513730 Bos taurus
58065 Danio rerio
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