anti-Rhesusaffen Tumor Necrosis Factor Antikörper für Immunohistochemistry (Frozen Sections)

Recommended Tumor Necrosis Factor Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Necrosis Factor (TNF) Antikörper
  • TNF
  • tnf
  • dif
  • tnfa
  • xtnf
  • TNF-a
  • tnfsf2
  • tnf-alpha
  • TNF-alpha
  • DIF
  • TNFA
  • TNFSF2
  • TNFalpha
  • Tnfa
  • Tnfsf1a
  • RATTNF
  • TNFa
  • cTNF
  • TNF-ALPHA
  • Cachectin
  • Tnf-alpha
  • tnfa-like
  • tumor necrosis factor (TNF superfamily, member 2)
  • tumor necrosis factor
  • tumour necrosis factor alpha-like
  • tumor necrosis factor alpha
  • lipopolysaccharide-induced TNF factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • TNF
  • tnf
  • tnf-alpha
  • LITAF
  • Tnf
  • tnfb
Reaktivität
Meerschweinchen, Human, Maus, Rhesusaffen
1250
460
359
145
136
119
119
63
55
41
29
18
14
11
9
6
6
4
4
4
4
2
1
1
1
1
Wirt
Maus
934
519
184
48
10
9
7
6
4
3
2
Klonalität
Monoklonal
Konjugat
Dieser Tumor Necrosis Factor Antikörper ist konjugiert mit FITC
169
99
74
50
32
30
28
27
26
25
25
25
25
25
24
24
24
23
13
9
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Applikation
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
887
857
622
320
287
229
219
190
138
118
97
69
29
29
26
22
20
18
14
9
7
7
6
6
6
5
5
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
Hersteller
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Produktnummer ABIN1109408
495,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1109397 IHC (fro) IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 52B83 5
1 ABIN3201324 ICC IHC (fro) IHC (p) ELISA WB Mouse IgG AA 77-233 Anmelden zum Anzeigen

General

Antigen Tumor Necrosis Factor (TNF) Antikörper
Reaktivität Meerschweinchen, Human, Maus, Rhesusaffen
(1250), (460), (359), (145), (136), (119), (119), (63), (55), (41), (29), (18), (14), (11), (9), (6), (6), (4), (4), (4), (4), (2), (1), (1), (1), (1)
Wirt Maus
(934), (519), (184), (48), (10), (9), (7), (6), (4), (3), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Tumor Necrosis Factor Antikörper ist konjugiert mit FITC
(169), (99), (74), (50), (32), (30), (28), (27), (26), (25), (25), (25), (25), (25), (24), (24), (24), (23), (13), (9), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(887), (857), (622), (320), (287), (229), (219), (190), (138), (118), (97), (69), (29), (29), (26), (22), (20), (18), (14), (9), (7), (7), (6), (6), (6), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Tumor Necrosis Factor Antikörper

Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN1109408) Bilder
Kreuzreaktivität (Details) Species reactivity (tested):Human, mouse, guinea pig, rhesus monkey
Reinigung Protein G
Klon 52B83
Isotyp IgG1

Target Details Tumor Necrosis Factor

Produktdetails anti-Tumor Necrosis Factor Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN1109408) Bilder zurück nach oben
Antigen
Andere Bezeichnung Tumor Necrosis Factor (TNF-Alpha) (TNF Antibody Abstract)
Hintergrund TNF-alpha is a homotrimeric 17 kDa protein, that interacts with either one of the two types of TNF-receptors, termed I and II, leading to receptor cross-linking and signal transduction. The receptors differ strongly in their intra-cellular signaling pathways. TNF-alpha was originally described as a highly cytotoxic cytokine for tumor cells, it causes tumor necrosis in vivo and shows cytolytic activity against tumor cells in vitro. Furthermore, TNF-alpha is found to be a central mediator in many inflammatory and immunological processes. It can be induced by various products of micro-organisms and by various cytokines leading to expression of a wide variety of cytokines. The pro-inflammatory properties of TNF-alpha play a central role in several auto-immune diseases such as rheumatoid arthritis and inhibition by neutralizing molecules have been shown to be beneficial in patients.Synonyms: Cachectin, TNF, TNF-a, TNFA, TNFSF2, Tumor necrosis factor ligand superfamily member 2
UniProt P01375
Forschungsgebiet Cytokines, Growth Factors, Receptors, Immunology, Inflammation, Cancer, Virology
Pathways NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus

Anwendungsinformationen

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Handhabung ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN1109408) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN1109408) Bilder zurück nach oben
Konzentration 0.1 mg/mL
Buffer PBS, 0.02 % sodium azide, 1 % bovine serum albumin
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 2 - 8 °C.

ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN1109408)

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Lee, Cho, Park: "Clinical and immunohistochemical characteristics of mucoceles." in: Annals of dermatology, Vol. 21, Issue 4, pp. 345-51, 2010

van der Laan, de Leij, Buurman, Timens, ten Duis: "Tumor necrosis factor alpha (TNFalpha) in human skin: a comparison of different antibodies for immunohistochemistry." in: Archives of dermatological research, Vol. 293, Issue 5, pp. 226-32, 2001

Gerspach, Götz, Zimmermann, Kolle, Böttinger, Grell: "Detection of membrane-bound tumor necrosis factor (TNF): an analysis of TNF-specific reagents." in: Microscopy research and technique, Vol. 50, Issue 3, pp. 243-50, 2000

Bradding, Mediwake, Feather, Madden, Church, Holgate, Howarth: "TNF alpha is localized to nasal mucosal mast cells and is released in acute allergic rhinitis." in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, Vol. 25, Issue 5, pp. 406-15, 1995

Bradding, Roberts, Britten, Montefort, Djukanovic, Mueller, Heusser, Howarth, Holgate: "Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines." in: American journal of respiratory cell and molecular biology, Vol. 10, Issue 5, pp. 471-80, 1994