anti-Ratte (Rattus) Tumor Necrosis Factor Antikörper für Intracellular Flow Cytometry

Recommended Tumor Necrosis Factor Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Necrosis Factor (TNF) Antikörper
  • TNF
  • tnf
  • dif
  • tnfa
  • xtnf
  • TNF-a
  • tnfsf2
  • tnf-alpha
  • TNF-alpha
  • DIF
  • TNFA
  • TNFSF2
  • TNFalpha
  • Tnfa
  • Tnfsf1a
  • RATTNF
  • TNFa
  • cTNF
  • TNF-ALPHA
  • Cachectin
  • Tnf-alpha
  • tnfa-like
  • tumor necrosis factor (TNF superfamily, member 2)
  • tumor necrosis factor
  • tumour necrosis factor alpha-like
  • tumor necrosis factor alpha
  • lipopolysaccharide-induced TNF factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • TNF
  • tnf
  • tnf-alpha
  • LITAF
  • Tnf
  • tnfb
Reaktivität
Maus, Ratte (Rattus)
1255
459
357
145
136
119
119
63
55
41
29
18
14
12
9
7
6
4
4
4
4
2
1
1
1
1
Wirt
Hamster
940
516
184
48
10
9
6
6
4
3
2
Klonalität
Monoklonal
Konjugat
Dieser Tumor Necrosis Factor Antikörper ist unkonjugiert
169
100
74
50
32
30
28
27
26
25
25
25
25
25
24
24
24
23
13
9
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Applikation
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
887
859
621
322
286
230
219
190
137
118
98
74
29
27
26
22
20
18
14
9
7
7
6
6
6
5
5
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN2665424
238,12 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN2665423 FACS ICFC Hamster IgG Anmelden zum Anzeigen TN3-19-12 9

anti-Tumor Necrosis Factor Antikörper für Intracellular Flow Cytometry mit den meisten Publikationen

Ähnliche anti-Tumor Necrosis Factor Antikörper

Applikation / Reaktivität Ratte (Rattus)
Blocking Antibody (Inhibition) 3 Antikörper
Blocking Peptide (BP) 1 Antikörper
Cytometry by Time of Flight (CyTOF) 18 Antikörper
Dot Blot (DB) 1 Antikörper
ELISA 128 Antikörper
ELISpot 2 Antikörper
Enzyme Immunoassay (EIA) 7 Antikörper
Flow Cytometry (FACS) 197 Antikörper
Functional Studies (Func) 8 Antikörper
Immunochromatography (IC) 1 Antikörper
Immunocytochemistry (ICC) 112 Antikörper
Immunofluorescence (IF) 148 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 3 Antikörper
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antikörper
Immunohistochemistry (IHC) 61 Antikörper

General

Antigen Tumor Necrosis Factor (TNF) Antikörper
Reaktivität Maus, Ratte (Rattus)
(1255), (459), (357), (145), (136), (119), (119), (63), (55), (41), (29), (18), (14), (12), (9), (7), (6), (4), (4), (4), (4), (2), (1), (1), (1), (1)
Wirt Hamster
(940), (516), (184), (48), (10), (9), (6), (6), (4), (3), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Tumor Necrosis Factor Antikörper ist unkonjugiert
(169), (100), (74), (50), (32), (30), (28), (27), (26), (25), (25), (25), (25), (25), (24), (24), (24), (23), (13), (9), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
(887), (859), (621), (322), (286), (230), (219), (190), (137), (118), (98), (74), (29), (27), (26), (22), (20), (18), (14), (9), (7), (7), (6), (6), (6), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 9 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Tumor Necrosis Factor Antikörper

Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN2665424) Bilder
Kreuzreaktivität Kaninchen
Reinigung The antibody was purified by affinity chromatography.
Klon TN3-19-12
Isotyp IgG

Target Details Tumor Necrosis Factor

Produktdetails anti-Tumor Necrosis Factor Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN2665424) Bilder zurück nach oben
Antigen
Andere Bezeichnung TNF-alpha (TNF Antibody Abstract)
Hintergrund TNF-α is secreted by macrophages, monocytes, neutrophils, T-cells (principally CD4+), and NK-cells. Many transformed cell lines also secrete TNF-α. Monomeric mouse TNF-α is 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD protein. TNF-α forms multimeric complexes, stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorraghic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils. The TN3-19.12 antibody reacts with mouse, rat, and rabbit tumor-necrosis factor-α (TNF-α) proteins. The TN3-19.12 antibody can neutralize the bioactivity of natural or recombinant TNF-α.
Forschungsgebiet Inflammation, Cancer, Virology
Pathways NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus

Anwendungsinformationen

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Handhabung ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN2665424) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN2665424) Bilder zurück nach oben
Konzentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN2665424)

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Simkins, Hyde, Farrand, Ong, Degli-Esposti, Hermans, Ronchese: "Administration of alpha-galactosylceramide impairs the survival of dendritic cell subpopulations in vivo." in: Journal of leukocyte biology, Vol. 89, Issue 5, pp. 753-62, 2011

Takahashi, Kapás, Fang, Krueger: "An anti-tumor necrosis factor antibody suppresses sleep in rats and rabbits." in: Brain research, Vol. 690, Issue 2, pp. 241-4, 1996

Rabinovici, Bugelski, Esser, Hillegass, Griswold, Vernick, Feuerstein: "Tumor necrosis factor-alpha mediates endotoxin-induced lung injury in platelet activating factor-primed rats." in: The Journal of pharmacology and experimental therapeutics, Vol. 267, Issue 3, pp. 1550-7, 1994

Tracey, Cerami: "Tumor necrosis factor: an updated review of its biology." in: Critical care medicine, Vol. 21, Issue 10 Suppl, pp. S415-22, 1993

Molloy, ORiordain, Holzheimer, Nestor, Collins, Mannick, Rodrick: "Mechanism of increased tumor necrosis factor production after thermal injury. Altered sensitivity to PGE2 and immunomodulation with indomethacin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 4, pp. 2142-9, 1993

Merrick, He, Craig, Clark, Corsini, Rosenthal, Mansfield, Selkirk: "Two dimensional gel electrophoresis of cellular and secreted proteins from rat alveolar macrophages after lipopolysaccharide treatment." in: Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society, Vol. 2, Issue 6, pp. 177-87, 1992

Beutler, Cerami: "The biology of cachectin/TNF--a primary mediator of the host response." in: Annual review of immunology, Vol. 7, pp. 625-55, 1989

Sheehan, Ruddle, Schreiber: "Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 11, pp. 3884-93, 1989

Beutler, Cerami: "Tumor necrosis, cachexia, shock, and inflammation: a common mediator." in: Annual review of biochemistry, Vol. 57, pp. 505-18, 1988

Bilder

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN2665424) zurück nach oben
Bilder des Herstellers
ELISA image for anti-Tumor Necrosis Factor Antikörper (TNF) (ABIN2665424) anti-Tumor Necrosis Factor (TNF) antibody
ELISA image for anti-Tumor Necrosis Factor Antikörper (TNF) (ABIN2665424) anti-Tumor Necrosis Factor (TNF) antibody (Image 2)