anti-Human Tumor Necrosis Factor Antikörper für Neutralization

Recommended Tumor Necrosis Factor Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Necrosis Factor (TNF) Antikörper
  • DIF
  • TNF-alpha
  • TNFA
  • TNFSF2
  • RATTNF
  • Tnfa
  • tnf
  • TNF-a
  • TNFalpha
  • Tnfsf1a
  • TNFa
  • cTNF
  • Tnf-alpha
  • tnfa-like
  • TNF-ALPHA
  • dif
  • tnfa
  • xtnf
  • tnfsf2
  • tnf-alpha
  • Cachectin
  • tumor necrosis factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • tumour necrosis factor alpha-like
  • tumor necrosis factor alpha
  • lipopolysaccharide induced TNF factor
  • tumor necrosis factor a (TNF superfamily, member 2)
  • TNF
  • Tnf
  • tnf
  • tnfb
  • tnf-alpha
  • LITAF
  • LOC103694380
  • tnfa
Reaktivität
Human
1252
462
357
144
136
119
118
62
54
41
29
17
14
12
9
7
6
4
4
4
3
2
1
1
1
1
Wirt
Kaninchen
937
519
184
46
10
9
7
5
4
3
2
Klonalität
Polyklonal
Konjugat
Dieser Tumor Necrosis Factor Antikörper ist unkonjugiert
168
100
74
50
32
30
28
27
26
25
25
25
25
25
24
24
24
23
13
9
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Applikation
Neutralization (Neut), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
886
854
624
323
284
230
220
190
136
118
97
69
29
29
26
22
20
18
14
9
7
7
6
6
6
6
5
5
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Optionen
Hersteller
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Produktnummer ABIN1043796
$ 139.00
Zzgl. Versandkosten $45.00 und $23.00 Trockeneis
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN1176946 Neut ELISA Mouse IgG1 Anmelden zum Anzeigen MAb1 2
1 ABIN1177286 Neut ELISA Mouse IgG2a, kappa Anmelden zum Anzeigen MABTNF-A5 3
1 ABIN222906 IHC Neut WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN465605 ELISA IHC (p) Neut Mouse IgG1 Anmelden zum Anzeigen
1 ABIN1449154 Neut Mouse IgG1 Anmelden zum Anzeigen #1
1 ABIN2682656 Neut Rabbit IgG AA 77-233 Anmelden zum Anzeigen R101
1 ABIN107946 IHC Neut ELISA WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN465030 ELISA IHC (p) Neut WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN465674 IHC (p) Neut ELISA WB Goat Anmelden zum Anzeigen Polyclonal
1 ABIN5526231 ELISA Neut HRP Mammalian Cells IgG4 kappa Anmelden zum Anzeigen CDP 571
1 ABIN1104720 IHC (p) Neut WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN3026402 FACS IF InhA Neut Mouse IgG1, kappa Anmelden zum Anzeigen J1D9
1 ABIN3026400 FACS IF InhA Neut Mouse IgG1, kappa Anmelden zum Anzeigen J2D10
1 ABIN1959982 BR ELISA Func Neut WB Mouse IgG1 Anmelden zum Anzeigen MAb1
1 ABIN1967143 BR ELISA Func Neut WB Mouse IgG1 Anmelden zum Anzeigen MAb1
1 ABIN1959983 BR ELISA FACS Func ICC IHC (fro) Neut Mouse IgG1 Anmelden zum Anzeigen MAb11
1 ABIN5508607 Neut Mouse IgG1 AA 77-233 Anmelden zum Anzeigen MM0N1
1 ABIN4964979 ELISA Neut Human IgG1 Anmelden zum Anzeigen
1 ABIN3023865 FACS IF Neut IHC (p) ELISA Mouse IgM, kappa Anmelden zum Anzeigen MAb1
1 ABIN1983231 Neut IHC WB Mouse IgG1 AA 57-233 Anmelden zum Anzeigen MM0327-7J20

General

Antigen Tumor Necrosis Factor (TNF) Antikörper
Reaktivität Human
(1252), (462), (357), (144), (136), (119), (118), (62), (54), (41), (29), (17), (14), (12), (9), (7), (6), (4), (4), (4), (3), (2), (1), (1), (1), (1)
Wirt Kaninchen
(937), (519), (184), (46), (10), (9), (7), (5), (4), (3), (2)
Klonalität
Polyklonal
Konjugat Dieser Tumor Necrosis Factor Antikörper ist unkonjugiert
(168), (100), (74), (50), (32), (30), (28), (27), (26), (25), (25), (25), (25), (25), (24), (24), (24), (23), (13), (9), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Neutralization (Neut), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(886), (854), (624), (323), (284), (230), (220), (190), (136), (118), (97), (69), (29), (29), (26), (22), (20), (18), (14), (9), (7), (7), (6), (6), (6), (6), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 Publikation vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Tumor Necrosis Factor Antikörper

Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN1043796) Bilder
Spezifität This antibody is primarily directed against mature 17,000 MW human TNFalpha and is useful in determining its presence in various assays. In general, this antibody also detects primate TNFalpha in the same formats using similar dilutions. The antibody does not recognize human TNGß (lymphotoxin). This IgG fraction antibody will recognize the cell-bound precursor of TNFalpha as a 26,000 protein in immunoblots, particularly in denatured samples. This antibody is also useful for neutralization of human and primate TNFalpha activity in bioassays. It does not neutralize the biological activity of lymphotoxin. For neutralization, it is recommended to incubate the sample with a 1:200 dilution of the antibody for at least 4 hours before being tested. A control of similarly diluted normal rabbit IgG is recommended.
Produktmerkmale Anti TNF alpha Antibody recognizes TNF alpha (TNF, cachexin, cachectin, tumor necrosis factor-alpha or TNF-alpha) a cytokine involved in systemic inflammation. TNF alpha is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. The primary role of TNF alpha is in the regulation of immune cells. TNFis an endogenous pyrogen that is able to induce fever, apoptotic cell death, sepsis (through IL-1 & IL-6 production), cachexia, inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNF production has been implicated in a variety of human diseases, including Alzheimer's disease, cancer, major depression, and inflammatory bowel disease (IBD).
Sterilität Sterile filtered
Immunogen The whole rabbit serum used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant human TNFalpha produced in E.coli.
Immunogen Type: RecombinantProtein
Isotyp IgG

Target Details Tumor Necrosis Factor

Produktdetails anti-Tumor Necrosis Factor Antikörper Anwendungsinformationen Handhabung Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN1043796) Bilder zurück nach oben
Antigen
Andere Bezeichnung TNF alpha (TNF Antibody Abstract)
Hintergrund Anti TNF alpha Antibody recognizes TNF alpha (TNF, cachexin, cachectin, tumor necrosis factor-alpha or TNF-α) a cytokine involved in systemic inflammation. TNF alpha is a member of a group of cytokines that stimulate the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. The primary role of TNF alpha is in the regulation of immune cells. TNFis an endogenous pyrogen that is able to induce fever, apoptotic cell death, sepsis (through IL-1 & IL-6 production), cachexia, inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNF production has been implicated in a variety of human diseases, including Alzheimer's disease, cancer, major depression, and inflammatory bowel disease (IBD).
Synonyms: APC1 antibody, Cachectin antibody, DIF antibody, Differentiation inducing factor antibody, Macrophage cytotoxic factor antibody, MCF antibody, Necrosin antibody
Gen-ID 7124
UniProt P01375
Forschungsgebiet Cardiovascular, Atherosclerosis, Growth Factors, Innate Immunity, Cytokines, Receptors, Immunology, Inflammation, Cancer, Virology
Pathways NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus

Anwendungsinformationen

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Handhabung Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN1043796) Bilder zurück nach oben
Applikationshinweise This IgG fraction antibody of anti-Human TNFα has been tested for use in neutralizations, ELISA, immunohistochemistry and immunoblotting. It recognizes the 17,000 MW TNFα. Reactivity in other immunoassays is unknown.
Kommentare

Gene Name: TNFA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN1043796) Bilder zurück nach oben
Format Liquid
Konzentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Konservierungsmittel Without preservative
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Haltbarkeit 12 months

Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN1043796)

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Kant, Swat, Zhang, Zhang, Neel, Flavell, Davis: "TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathway." in: Genes & development, Vol. 25, Issue 19, pp. 2069-78, 2011

Bilder

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung Referenzen für anti-Tumor Necrosis Factor Antikörper (ABIN1043796) zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN1043796) Immunohistochemistry using polyclonal TNFa antibody showing staining of formalin/PFA-...
 image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN1043796) anti-Tumor Necrosis Factor (TNF) antibody (Image 2)
 image for anti-Tumor Necrosis Factor (TNF) antibody (ABIN1043796) anti-Tumor Necrosis Factor (TNF) antibody (Image 3)