anti-Human Tumor Necrosis Factor Antikörper für Biochemical Assay

Recommended Tumor Necrosis Factor Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Necrosis Factor (TNF) Antikörper
  • TNF
  • tnf
  • dif
  • tnfa
  • xtnf
  • TNF-a
  • tnfsf2
  • tnf-alpha
  • TNF-alpha
  • DIF
  • TNFA
  • TNFSF2
  • TNFalpha
  • Tnfa
  • Tnfsf1a
  • RATTNF
  • TNFa
  • cTNF
  • TNF-ALPHA
  • Cachectin
  • Tnf-alpha
  • tnfa-like
  • tumor necrosis factor (TNF superfamily, member 2)
  • tumor necrosis factor
  • tumour necrosis factor alpha-like
  • tumor necrosis factor alpha
  • lipopolysaccharide-induced TNF factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • TNF
  • tnf
  • tnf-alpha
  • LITAF
  • Tnf
  • tnfb
Reaktivität
Human
1254
460
358
145
136
119
119
63
55
41
29
18
14
12
9
7
6
4
4
4
4
2
1
1
1
1
Wirt
Maus
939
516
184
48
10
9
7
6
4
3
2
Klonalität
Monoklonal
Konjugat
Dieser Tumor Necrosis Factor Antikörper ist unkonjugiert
169
100
74
50
32
30
28
27
26
25
25
25
25
25
24
24
24
23
13
9
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
Applikation
Biochemical Assay (BCA)
887
859
622
322
286
230
219
190
137
118
98
74
29
27
26
22
20
18
14
9
7
7
6
6
6
5
5
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN2665427
124,24 €
Zzgl. Versandkosten 20,00 € und MWSt

anti-Tumor Necrosis Factor Antikörper für Biochemical Assay mit den meisten Publikationen

Ähnliche anti-Tumor Necrosis Factor Antikörper

Applikation / Reaktivität Human
Activity Inhibition (Act Inh) 2 Antikörper
Biochemical Assay (BCA) 1 Antikörper
Blocking Antibody (Inhibition) 13 Antikörper
Blocking Peptide (BP) 6 Antikörper
Blocking Reagent (BR) 5 Antikörper
Cell Culture (CC) 1 Antikörper
Cellular Assay (CA) 2 Antikörper
Cytometry by Time of Flight (CyTOF) 27 Antikörper
Dot Blot (DB) 2 Antikörper
ELISA 593 Antikörper
ELISA (Capture) 6 Antikörper
ELISA (Detection) 4 Antikörper
ELISpot 9 Antikörper
ELISpot (Capture) (ELISPOT (Capture)) 1 Antikörper
ELISpot (Detection) (ELISPOT (Detection)) 1 Antikörper
Enzyme Immunoassay (EIA) 49 Antikörper
Flow Cytometry (FACS) 519 Antikörper
Functional Studies (Func) 68 Antikörper
Immunoassay (IA) 15 Antikörper

General

Antigen Tumor Necrosis Factor (TNF) Antikörper
Reaktivität Human
(1254), (460), (358), (145), (136), (119), (119), (63), (55), (41), (29), (18), (14), (12), (9), (7), (6), (4), (4), (4), (4), (2), (1), (1), (1), (1)
Wirt Maus
(939), (516), (184), (48), (10), (9), (7), (6), (4), (3), (2)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser Tumor Necrosis Factor Antikörper ist unkonjugiert
(169), (100), (74), (50), (32), (30), (28), (27), (26), (25), (25), (25), (25), (25), (24), (24), (24), (23), (13), (9), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Applikation Biochemical Assay (BCA)
(887), (859), (622), (322), (286), (230), (219), (190), (137), (118), (98), (74), (29), (27), (26), (22), (20), (18), (14), (9), (7), (7), (6), (6), (6), (5), (5), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 10 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Tumor Necrosis Factor Antikörper

Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN2665427) Bilder
Kreuzreaktivität Schimpanse, Pavian, Cynomolgus, Rhesusaffen, Schwein, Pigtailed Macaque, Sooty mangabey (Cercocebus atys)
Reinigung The antibody was purified by affinity chromatography.
Klon MAb11
Isotyp IgG1 kappa

Target Details Tumor Necrosis Factor

Produktdetails anti-Tumor Necrosis Factor Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN2665427) Bilder zurück nach oben
Antigen
Andere Bezeichnung TNF-alpha (TNF Antibody Abstract)
Hintergrund TNF-α is secreted by macrophages, monocytes, neutrophils, T cells (principally CD4+), and NK cells. Many transformed cell lines also secrete TNF-α. Monomeric human TNF-α is a 157 amino acid protein (non-glycosylated) with a reported molecular weight of 17 kD. TNF-α forms multimeric complexes, stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biological activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorraghic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.
Forschungsgebiet Inflammation, Cancer, Virology
Pathways NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus

Anwendungsinformationen

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Handhabung ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN2665427) Bilder zurück nach oben
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN2665427) Bilder zurück nach oben
Konzentration 1.0 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung The antibody solution should be stored undiluted between 2°C and 8°C.

ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN2665427)

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Iwamoto, Iwai, Tsujiyama, Kurahashi, Takeshita, Naoe, Masunaga, Ogawa, Oguchi, Miyazaki: "TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 3, pp. 1449-57, 2007

Chen, Hou, Jiang, Ma, Meng, Wang, Zhang, Zhang, Tang, Zhang, Wan, Li, Yu, Hu, Yang, He, Wang, Cao: "Response of memory CD8+ T cells to severe acute respiratory syndrome (SARS) coronavirus in recovered SARS patients and healthy individuals." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 1, pp. 591-8, 2005

Enríquez, Klínger, Arturo, Delgado, Tobar, Mosquera: "Peritonitis in continuous ambulatory peritoneal dialysis: cytokines in peritoneal fluid and blood." in: Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, Vol. 18, pp. 177-83, 2002

Andersson, Wang, Palmblad, Aveberger, Bloom, Erlandsson-Harris, Janson, Kokkola, Zhang, Yang, Tracey: "High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes." in: The Journal of experimental medicine, Vol. 192, Issue 4, pp. 565-70, 2001

Moormann, Sullivan, Rochford, Chensue, Bock, Nyirenda, Meshnick: "Malaria and pregnancy: placental cytokine expression and its relationship to intrauterine growth retardation." in: The Journal of infectious diseases, Vol. 180, Issue 6, pp. 1987-93, 2000

Tracey, Cerami: "Tumor necrosis factor: an updated review of its biology." in: Critical care medicine, Vol. 21, Issue 10 Suppl, pp. S415-22, 1993

Rathjen, Cowan, Furphy, Aston: "Antigenic structure of human tumour necrosis factor: recognition of distinct regions of TNF alpha by different tumour cell receptors." in: Molecular immunology, Vol. 28, Issue 1-2, pp. 79-86, 1991

Danis, Franic, Rathjen, Brooks et al.: "Effects of granulocyte-macrophage colony-stimulating factor (GM-CSF), IL-2, interferon-gamma (IFN-gamma), tumour necrosis factor-alpha (TNF-alpha) and IL-6 on the production of immunoreactive IL-1 ..." in: Clinical and experimental immunology, Vol. 85, Issue 1, pp. 143-50, 1991

Beutler, Cerami: "The biology of cachectin/TNF--a primary mediator of the host response." in: Annual review of immunology, Vol. 7, pp. 625-55, 1989

Beutler, Cerami: "Tumor necrosis, cachexia, shock, and inflammation: a common mediator." in: Annual review of biochemistry, Vol. 57, pp. 505-18, 1988

Bilder

Produktdetails anti-Tumor Necrosis Factor Antikörper Target Details Tumor Necrosis Factor Anwendungsinformationen Handhabung ProductDetails: References for anti-Tumor Necrosis Factor antibody (ABIN2665427) zurück nach oben
Bilder des Herstellers
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor Antikörper (TNF) (ABIN2665427) anti-Tumor Necrosis Factor (TNF) antibody
Flow Cytometry (FACS) image for anti-Tumor Necrosis Factor Antikörper (TNF) (ABIN2665427) anti-Tumor Necrosis Factor (TNF) antibody (Image 2)